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anti tubercular

QuestionAnswer
MOA OF ISONIAZID Inhibit synthesis of mycolic acid
ISONIAZID AE Hepatic damage,Peripheral neuritis
CONTRA ISONIAZID Hypersensitivity Liver disease
RIFAMPIN MOA Inhibit binding of enzyme to DNA
RIFAMPIN AE Hepatotoxicity,Red orange discoloration of urine, tears, saliva
ETHAMBUTOL MOA Inhibit glycan synthesis Inhibit RNA synthesis Bacteriostatic
ETHAMBUTOL AE Optic neuritis Hepatic toxicity Reduction in red-green visual acuity
ETHAMBUTOL CONTRA Hypersensitivity  Optic neuritis
PYRAZINAMIDE ABSORB ORALLY
PYRAZINAMIDE MOA Converted to pyrazinoic acid (active agent)  Bacteriostatic
PYRAZINAMIDE AE Hyperuricemia  Hepatotoxicity  Photosensitivity
STREPTOMYCIN MOA Bactericidal 30S ribosomal inhibitor of protein synthesis
STREPTOMYCIN ONLY CAN BE GIVEN BY IM injection
STRPTOMYCIN AE Nephrotoxicity  Ototoxicity
STRPTOMYCIN CONTRA Hypersensitivity  pregnancy
Created by: 100001968901555
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