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Das Cytokines
| Question | Answer |
|---|---|
| IL-1: secreted | Macs, endothelium |
| IL-1: Primary target | Increases CAMs, Activates macs |
| IL-1: Hallmark | Pro-Inflammatory |
| IL-2: secreted | Th cells |
| IL-2: primary target | Th1, Tc, NK cells |
| IL-2: Hallmark | Th1 cytokine |
| IL-4:secreted | Th2 cells |
| IL-4:target | Th2 cells, B cells |
| IL-4: Hallmark | Th2 cytokine |
| IL-6:secreted | Macs Th2 cells |
| IL-6:target | Th2 cells, B cells |
| IL-6:hallmark | ProInflam/Th2 |
| IL-7:secreted | Bone marrow |
| IL-7:target | Stem cells |
| IL-7:hallmark | Hematopoiesis |
| IL-8:secreted | Neutrophils |
| IL-8:target | Endothelial cells |
| IL-8:hallmark | Chemokine |
| IL-10:secreted | Th2 cells, |
| IL-10:target | Macs, Th2 and B cells |
| IL-10:hallmark | Th2 cytokine |
| IL-12:secreted | Macrophages, dendritic cells |
| IL-12:target | Th1, Tc, NK cells |
| IL-12:hallmark | Th1 cytokine |
| TNF-alpha:secreted | Macs, T, B endothelial |
| TNF-alpha:target | tumor cells, macs,B cells, T cells |
| TNF-alpha:hallmark | Pro-Inflammatory |
| TNF-beta:secreted | Th1 cells |
| TNF-beta:target | macrophages, Th1 cells, |
| TNF-beta:hallmark | Inflammatory |
| IFN-alpha/beta:secreted | Neutrophils, endo/epithelial |
| IFN-alpha/beta:target | Uninfected cells |
| IFN-alpha/beta:hallmark | Anti-viral cytokines |
| IFN gamma:secreted | Th1 cells, macrophages |
| IFN gamma:target | macrophages, Th1 |
| IFN gamma:hallmark | Th1 cytokine Inflammatory |