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Biochem fall11

QuestionAnswer
Which ONE of the following is a ketose with 6 carbons? Fructose
The reactions catalyzed by Pyruvate dehydrogenase, Pyruvate decarboxylase and α-Ketoglutarate dehydrogenase all use which one of the following to help catalyze the reaction? Thiamine pyrophosphate
Which ONE of the following is true regarding the reaction that converts hemoglobin to HbA1c? The rate of the reaction depends on the concentration of glucose in the blood
Which ONE of the following reactions is catalyzed by Lactase? Conversion of a reducing disaccharide to two reducing monosaccharides.
When cells are starved for glucose the NADH/NAD+ ratio in the cytoplasm becomes very low. Which ONE of the following would be most likely to accumulate in the cytoplasm under these conditions? Oxaloacetate
Which ONE of the following correctly describes the type of Glucose transporter and the type of Hexokinase in the β cells in the pancreas? Low affinity glucose transporter, low affinity hexokinase.
Which ONE of the following enzymes catalyzes a reaction that occurs during the “payoff” phase of glycolysis? Phosphoglycerate mutase
fructose in it without getting sick. They are OK eating starch or glycogen. Which ONE of the following is most likely to be the enzyme that is deficient in people with Fructose Intolerance? An enzyme that produces Dihydroxyacetone phosphate and Glyceraldehyde
Which ONE of the following is an intermediate in the “Investment” phase of glycolysis that starts with glucose? Fructose-6-phosphate
Which ONE of the following metabolites will accumulate in the cytoplasm of a cell in which pyruvate kinase activity is abnormally decreased? Phosphoenolpyruvate.
Which ONE of the following enzymes catalyzes a reaction in which Coenzyme A is a substrate and is part of the final product of the reaction? α-Ketoglutarate dehydrogenase
Which ONE of the following reactions catalyzes the phosphorylation of GDP to GTP? A reaction that produces Coenzyme A as one of its products.
Which ONE of the following TYPES of enzyme or transporter could move lactate out of a cell through the plasma membrane? A Monocarboxylate transporter
Which ONE of the following enzymes involved in the Krebs Cycle produces a tricarboxylic acid as one of the products of the reaction it catalyzes? Citrate Synthase.
Which ONE of the following stimulates an increase of 2,3- Bisphosphoglycerate in erythrocytes? A decrease in the concentration of HCO3 - in the blood.
Formic acid is an inhibitor of cytochrome oxidase. It blocks respiration and causes depression of neuronal activity. Which ONE of the following would be the most effective treatment for methanol poisoning? Ethanol.
Hydroxylation of a proline on HIF-1 decreases the rate of transcription of all of the following genes except one. Which ONE? Pyruvate Dehydrogenase E2
Which ONE of the following molecules (a-d) is most oxidized? Or are all of the choices (a-d) in the same oxidation state (e). Carbon Dioxide
Which ONE the following statements about Glycolysis is true? When at equilibrium there is much more Dihydroxyacetone phosphate than Glyceraldehyde-3-phosphate in the reaction catalyzed by Triose phosphate isomerase.
Which ONE of the following (a-d) correctly describes the relationship between ATP and Phosphofructokinase I (PFK-1)? Or do none of the choices (a-d) correctly describe the relationship? ATP is both a substrate and an allosteric regulator of Phosphofructokinase I
Which ONE of the following (a-d) correctly describes the influence of Fructose-1,6-bisphosphate (F1,6BP) on Pyruvate kinase activity? Or do none of the choices (a-d) correctly describe its influence? The effect of F1,6BP on Pyruvate Kinase is opposite to the effect of Alanine on Pyruvate kinase
A chemical, coprine, in this mushroom produces a metabolite that inhibits an enzyme in the liver. Which ONE of the following options is most likely to be that enzyme? Aldehyde dehydrogenase
Each of these enzymes makes products. Which ONE makes a product that yields the greatest free energy change when phosphate is hydrolyzed from that product under standard conditions? Enolase
Which ONE of the following enzymes or transport mechanisms helps to get reducing power from cytoplasmic NADH into mitochondria? Malate-aspartate shuttle
Which ONE of the following statements (a-d) about the F1F0 ATP synthase molecule is correct? Or are none of the other statements correct (e)? F1F0 ATP synthase uses a transmembrane proton gradient to drive conformational changes in the αβ heterodimer of the F1 subunit
Created by: c13luong
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