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PATH-DvlpmntlDis.

Development Disorders

QuestionAnswer
what are developmental disorders (on a cellular level)? a failure or disturbance that occurs during the process of fertilization, cell divison and differentiation into various tissues and structures -may result on lack of, excess of or deformity
what are the two types of developmental disorders? inherited and congenital disorders
what is inherited disorder? caused by an abnormality in genetic makeup transmitted from parent to offspring
what is congenital disorder? present at birth may be inherited or developmental complexity of cell division and specialization
head.neck regions are common areas for what? pattern of development frontal process and maxillary process fusing
what is the cause of most congenital abnormalities? unknown
(T/F) the frontal process is superior true
the 1st branchial arch is below what processes? 2 maxillary processes and the mandibular process
when is the stomodeum (primitive oral cavity) formed? 3rd week -in utero, ectoderm invaginates
what forms the philtrum? the median nasal process growing downward b/t maxillary processes to form globular process
what develops on the frontal process? 2 olfactories
what three parts is the frontal process divided into? median nasal process, right lateral nasal process, left lateral nasal process
what does the premaxilla form from? globular process
what does the lateral palatine processes form from? maxillary process
lateral palatine processes fuse with the premaxilla creating what pattern? Y-shaped
the nasal septum arises from what process? median nasal process
the body of the tongue develops from what branchial arch 1st branchial arch
the base of the tongue forms from what branchial arches? 2nd and 3rd branchial arches
when does odontogenesis begin? 5th week in utero
summary of odontogenesis? involves ectoderm and ectomesenchyme beings w/ formation of a band of ectoderm in ea. jaw (primary dental lamina--20 tooth germs)
what are the 3 parts of a tooth germ? enamel organ, dental papilla, dental sac/follicle
what does the enamel organ do? produces enamel
what does the dental papilla do? forms the dental pulp
what does the dental sac/follicle do? follicle provides cells that form cementum, PDL and alveolar bone
when is cementum formed? after the crown is complete
what do Hertwig's epithelial roots sheath do? shapes root of tooth introduces the formation of root dentin
name 3 developmental soft tissue abnormalities ankyloglossia, commissural lip pits, lingual thyroid
what is ankyloglossia? an extensive adhesion of the tongue to the floor of the mouth -may cause recession and bone loss
what is the cause of ankyloglossia? the complete of partial fusion of the lingual frenum
(T/F) ankyloglossia only involves mucosa False. may involve mucosa or may be muscular
what is the tx for ankyloglossia frenectomy
what is the tx for commissural lip pits? none
what are commissural lip pits? epithelium-lined blind tracts located at corners of mouth (commissure) incomplete fusion of max.man processes
what else is seen near the midline of the vermillion border when dealing with commissural lip pits congenital lip pits
what is lingual thyroid and what is it also known as? small nodular mass of thyroid tissue located posterior to the circumallate papillae
what is lingual thyroid caused by failure of primitive thyroid tissue to migrate from its developmental location in the area of foramen cecum on posterior portion of the tongue to its normal position in the neck -asymptomatic, difficultly swallowing
name 3 developmental cysts odontogenic cysts, nonodontogenic cysts, pseudocysts
what are developmental cysts an abnormal fluid-filled epithelium-lined sac or cavity, encapsulated in CT
where are developmental cysts found throughout the body, including the head and neck region
how are cysts classified? (4 ways) location, cause, origin of epithelial cells, histologic appearance
why are large cysts dangers? they can resorb and move teeth
what is intraosseous? within bone
what is extraosseous? in soft tissue
how do cysts (within bone) appear radiographically? well-circumscribed radiolucenies uniocular or mutliocular
what are odontogenic cysts--related to tooth development? dentigerous cyst, eruption cyst, primordial cyst, odontogenic keratocyst, calcifying cyst, lateral periodontal cyst, gingival cyst
what is a dentigerous cyst and what is it also known as? forms around the crown of an unerupted or developing tooth aka. follicular cyst
where is a dentigerous cyst most often found? crown of unerupted or impacted 3rd molars
how is a dentigerous cyst developed? epithelial lining originates from the reduced enamel epithelium after the crown has formed and calcified
how does a dentigerous cyst appear radiographically? well defined, unilocular, radiolucency around crown of unerupted/impacted tooth
how does a dentigerous cyst appear histologically? lumen is most characteristically lined w/ cuboidal epithelium surrounded by wall of CT
what is the tx for dentigerous cyst? removal or cyst -some risk of cystic transformation into neoplasm
eruption cysts are similar to what other odontogenic cyst? dentigerous cyst
where are eruption cysts found? found in the soft tissue around the crown of an erupting tooth -tooth erupts through the cyst or cyst is open to expose the crown
what is the tx for eruption cysts? none
where do primordial cysts develop? in the place of the tooth
where are primordial cysts most commonly developed? in place of 3rd molars
other random shit about primordial cyst most often seen in young adults discovered on radiographic examination Dx-tooth was never present
what is the tx for primordial cysts? surgical removal of entire lesion risk of recurrence depends on Dx
how might a primordial cyst appear histologically? may prove to be an odontogenic keratocyst or a lateral periodontal cyst
where are odontogenic keratocyst most often found? mandibular 3rd molar region
what type of lesion is odontogenic keratocyst ? expansive lesion (can move teeth and cause resorption)
how do odontogenic keratocysts appear radiographically? well defined, multiocular radiolucent lesion
how do odontogenic keratocyst appear histologically? parakeratin present, prominent palisaded basal layer
what is the tx for odontogenic keratocyst? surgical excision and osseous curettage (high recurrance rate)
what is a calcifying odontogenic cyst? nonaggressive, cystic lesion lined by odontogenic epithelium -microscopic charact. called ghost cells
what do odonotogenic tumor does calcifying odontogenic cysts resemble? ameloblastoma
where are lateral periodontal and gingival cysts most often seen? mandibular cuspid and premolar area -note asympomatic
(T/F) lateral periodontal and ginigval cysts are most often found in females? False. most foten found in MALES
how do lateral periodontal and ginigval cysts appear radiographically? unilocular or multiocular radiolucent lesion on lateral surface of tooth root
(T/F) a gingival cyst has the same type of lining, but its located in soft tisse True -note a thin band of stratified squamous epithelium lines cyst
what is the tx for lateral periodontal and ginigval cysts? surgical excision
what are nonodontogenic cysts--not related to tooth development? (9 types) nasopalatine canal cyst, median palatine cyst, globulomaxillary cyst, median mandibular cyst, nasolabial cyst, brachial cleft cyst (lymphoepithelial cyst), epidermal cyst, dermoid cyst and benign cystic teratoma, thyroglossal tract cyst
where are nasopalatine canal cyst located and what is it also known as? located w/in nasopalatine canal or incisive papilla aka. incisive canal cyst
what is the tx for nasopalatine canal cyst? surgical excision especially before denture fabrication
who is most commonly seen with nasopalatine canal cysts? men b/t 40-60 yrs old
how else can the nasopalatine cyst appear? small, pink bulge near apices and b/t roots of max. central incisor on lingual surface
what is a median palatine cyst and where is it located? well defined, uniocular radiolucency, located in midline of hard palate
how does median palatine cyst appear histologically? lined w/ stratified squamous epithelium surrounded by dense fibrous CT -may be painful due to expansion of palate
what is the tx for median palatine cysts? surgical removal -recurrance rare
what are 3 types of pseudocysts? static bone cyst, simple bone cyst, aneurysmal bone cyst
what is the tx for globulomaxillary cyst? surgical removal
what is globulomaxillary cyst? well defined, PEAR SHAPED, found b/t roots of maxillary lateral incisor nd cuspid -was though to be fissural cyst, now believed to be odontogenic epithelial origin
what cyst is 4xs more common in females? nasolabial cysts
what are nasolabial cysts? soft tissue cysts
what cyst is thought to originate from lower anterior portion of nasolacrimal duct? nasolabial cyst
what is the tx for nasolabial cyst? surgical excisions
how do nasolabial cyst appear clinically? expansion or swelling in mucobuccal fold in area of maxillary canine and floor of nose
how do nasolabial cyst appear histologically? lined w/ pseudostratified, cililated columnar epithelium and multiple goblet cells
(T/F) a static bone cyst is a true cyst False, it is not
what is the tx for a static bone cyst? none
how do you Dx for a static bone cyst? found at the angle of the mandible
what is a static bone cyst also known as? stafne bone cyst
what is a static bone cyst? pseudocyst well-defined cystlike, observed radiographically in posterior region of mandible inferior to mandibular canal -acutally a defect, salivary gland tissue trapped during development of mandible
what is a simple bone cyst also known as? traumatic bone cyst
how does a simple bone cyst appear radiographically? scalloping around roots of teeth
what is the tx for simple bone cyst? curettage wall lining the void, bone fills in 6mth-1yr
what is a simple bone cyst? pathologic cavity in bone that isn't lined w/ epithelium, void w/ bone -may be associated w/ trauma
what is a aneurysmal bone cyst? pseudocyst consists of blood filled spaces surrounded bu mutlinucleated giant cells and fibrous CT
how does aneurysmal bone cyst appear radiographically? radiolucency, mutliocular, "honeycomb" or "soapbubble"
what is the tx for aneurysmal bone cyst? excision
Created by: 100000001783325