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Histology Fill In The Blanks

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In each blank, try to type in the word that is missing. If you've typed in the correct word, the blank will turn green.

If your not sure what answer should be entered, press the space bar and the next missing letter will be displayed.

When you are all done, you should look back over all your answers and review the ones in red. These ones in red are the ones which you needed help on.
Question: The thin connective tissue that the liver is known as what?Answer: 's capsule
Question: Exocrine function of the is what?Answer: Bile
Question: of bile?Answer: Aids in absorption of lipids from the intestine and the disposal of conjugated and degraded waste .
Question: Endocrine-like of the liver?Answer: Modifies structure and function of many hormones. (Vit. D, thyroxine, GH, insulin and )
Question: What are the 2 suppliers of blood to the ?Answer: Venous (portal) blood supply (75%) via the hepatic portal and arterial (25%) via the hepatic artery.
Question: What did the blood of the venous vein initially supply?Answer: intestines, pancreas, and
Question: what does portal contain?Answer: nutrients and toxic absorbed in the intestines, blood cells and breakdown products of blood cells from the spleen, endocrine secretions from the pancreas and enteroendocrine cells of the GI tract
Question: Hepatocytes are never fully exposed to _____ blood.Answer:
Question: What are parenchymaAnswer: plates of hepatocytes
Question: What are the 4 of the liver structure?Answer: parenchyma, connective tissue stroma, sinusoidal (hepatic sinusoids), perisinusoidal (spaces of Disse) spaces
Question: are perisinusoidal spaces located?Answer: the sinusoidal endothelium and the hepatocytes
Question: 3 ways to describe the of the liver as a functional unitAnswer: classic lobule, portal lobule, acinus
Question: What does a liver lobule consist of?Answer: hexagonal mass, stacks of anastomosing plates of hepatocytes separated by sinusoidal capillaries, centered on terminal hepatic venule, corners of lobule are the areas (portal canals) that contain the portal triads
Question: What is the of a portal lobule?Answer: bile production and
Question: What does a lobule consist of?Answer: triangular lobule: portal area in that contains bile duct, terminal hepatic venule (central vein) at each corner
Question: What does a acinus consist of?Answer: provides best correlation between blood perfusion, metabolic , and liver pathology... eliptical shape, short axis extends between 2 portal areas, long axis extends between 2 terminal hepatic venules
Question: describe liver acinus zone 1 .Answer: first to receive oxygen, nutrients, and from the blood, first to show effects of bile duct obstruction
Question: describe zone 3 liver cells.Answer: first to show effects of perfusion, last to respond to toxins and bile stasis
Question: describe type 2 acinus cells.Answer: intermediate zone 1 and 3
Question: What is the common name for Stellate sinusoidal ?Answer: Kupffer
Question: What is the space known as?Answer: of Disse
Question: The site of exchange of materials the blood and liver cells is what?Answer: Perisinusoidal (space of Disse)
Question: In the fetal liver, islands of blood forming cells are where?Answer: Perisinusoidal space (space of )
Question: Hepatic stellate cells are where?Answer: Perisinusoidal space (space of )
Question: Primary site of storage for hepatic Vit. A is in the cytoplasmic of what cells?Answer: Hepatic stellate
Question: Plasma that remains in the Perisinusoidal space (space of Disse) drains in to what space?Answer: of Mall
Question: Near the portal canals bile join to form the what?Answer: Intrhepatic ductules (canals of )
Question: Canals of are partially lined by what 2 cell types?Answer: Hepatocytes and
Question: What is the of bile secretion?Answer: Hepatocytes secrete bile into bile canaliculi, bile flows from the central vein towards the portal canal and into intrahepatic ductules. Intrahepatic ductules drain into interlobular bile ducts then to bile ducts and then on to the gall bladd
Question: The gallbladder has what features?Answer: simple columnar epithelium and the mucosa has abundant folds in which the epithelium is rich in .
Question: Contraction of smooth muscle of the is induced by what?Answer:
Question: What induces CCK to be from enteroendocrine cells?Answer: Presence of dietary fats in the intestines.
Question: The exocrine portion of the pancreas is where?Answer: the pancreas
Question: The endocrine portion of the pancreas is where?Answer: of Langerhans
Question: Acini are of what?Answer: Serous cells surrounding a .
Question: Acinar store and what?Answer:
Question: does what?Answer: Cleaves into trypsin.
Question: secretion is controlled by what 2 hormones?Answer: Secretin and cholecystokinin (produced by cells of the intestinal mucosa) (duodenum and jejunum)
Question: What is a stimulus for secretin?Answer: acid (pH <4.5)
Question: Secretin has what ?Answer: causes duct cells to secrete large volume of that are rich in bicarbonate but has little enzyme effect (neutralizes the acid which allows for optimal pH for pancreatic enzymes)
Question: Cholecystokinin is released what initiates it?Answer: Long-chain fatty acids, gastric acid and certain amino .
Question: Islets of consists of what?Answer: Cords of polygonal invested with a network of fenestrated capillaries.
Question: Mallory-Azan technique can identify what cell ?Answer: cell types (A, B and D)
Question: silver stain can identify what?Answer: A
Question: cells secrete what?Answer: somatostatin
Question: Minor are what?Answer: PP cells (F cells), D-1 , EC cells
Question: PP secrete what?Answer: polypeptide
Question: D-1 secrete what?Answer: Vasoactive intestinal (VIP)
Question: EC cells what?Answer: , motilin and substance P
Question: What action does produce?Answer: insulin and glucogon secretion
 
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