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SZ Studies
Key studies for Schizophrenia
| Term | Definition |
|---|---|
| Cheniaux | Found very low inter-rater reliability between two psychiatrists. They diagnosed the same 100 people and found significant differences between their diagnoses, when using both ICD and DSM |
| Buckley | Found that 50% of people with SZ also had a depression diagnosis |
| Escobar | Found that white psychiatrists overdiagnose SZ in Afro Caribbean patients compared to white British patients, even though SZ is not significantly higher in Africa and the West Indies are not high |
| Longenecker | Reviewed studies of the prevalence of Schizophrenia and found that men had been diagnosed more often than women since the 1980s, suggesting a potential gender bias |
| Gottesman | Conducted family studies into Schizophrenia and found concordance rates of 48% for MZ twins, 17% for DZ twins, 9% for siblings and 6% between parents and children |
| Ripke | Found that there may be as many as 108 genes involved in the development of Schizophrenia, arguing against studies which show a 'gene for Schizophrenia' |
| Tienari | Adoption study found that 6.7% of adoptees whose birth mothers had SZ developed the condition, compared to just 2% of adoptee controls. Child-rearing style affected SZ, with criticism, conflict and low empathy associated with higher risk of SZ |
| Fromm-Reichmann | Developed the theory of the schizophrenogenic mother as a psychological explanation. Mothers who were particularly cold, rejecting and controlling were more likely to have Schizophrenic children |
| Read | Suggested that family dysfunction increased the chances of developing Schizophrenia. 69% of women and 59% of men with schizophrenia had some history of child abuse |
| Stirling | Those with an SZ diagnosis took more than twice as long to complete the Stroop Test compared to non-SZ controls |
| Thornley | Found that Chlorpromazine was more effective than a placebo, after reviewing data from 1,121 patients |
| Meltzer | Found that atypical antipsychotics (specifically Clozapine) were more effective than typical antipsychotics, and had fewer side effects |
| Jauhar | Reviewed studies into the effectiveness of CBT for schizophrenia and found that it had a small but significant effect on both positive and negative symptoms |
| McMonagle and Sultana | Reviewed studies into the effectiveness of token economies for treating schizophrenia. Only three used random allocation, and only one of these showed a positive outcome for the treatment |
| Tarrier | Found that a combination of medication + CBT/counselling reduced symptoms more than medication alone |
Created by:
SBlakeley
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