Toxidromes Word Scramble
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Question | Answer |
Define toxidrome. | A toxic syndrome made up of a constellation of signs and symptoms that consistently result from particular toxins. |
Name some common toxidromes. | Cholinergic. Anticholinergic. Narcotic/opioid. Sedative/hypnotic. Sympathomimetics. Hallicinogenics. |
What does a cholinergic toxidrome lead to? | Elevated levels of acetylcholine. |
What are common cholinergics? | Nicotine. Mushrooms. |
What are common anticholinesterases. | Organophosphates. Carbamate insecticides. Nerve gas (sarin). Urethanes. |
What are common organophosphates? | Nerve gasses. Insecticides. Herbicides. |
What are the symptoms of cholinergenic overdose. | DUMBELS= Diaphoresis, diarrhoea, decreased blood pressure. Urination. Miosis. Bronchorrhea, bronchospasm, bradicardia. Emesis, excitation of skeletal muscle. Lacrimation(tears). Salivation, seizures. |
What is the management for cholinergic toxidromes? | Atropine and supporting ABC's. |
What are anticholinergic drugs? | Drugs that generally interfere with the binding of acetylcholine to muscarinic receptors. |
What is the result of anticholinergic drugs affecting acetylcholine's binding? | The parasympathetic nervous system is inhibited or blocked. |
What are examples of anticholinergic drugs? | Atropine. Antihistamines. Antipsychotics. Antiparkinsons. TCA's. |
What are the symptoms of anticholinergic toxidromes? | Altered LOC: agitation, hallicinations. Mydriasis (pupil dilation) and blurred vision. Hot, dry, flushed skin - hyperthermia. Dry mucus membranes. Tachycardias'palpations,arryhythmias. GI: Urinary retention, decreased bowel sounds. |
What are the management for anicholinergic toxidromes? | Support ABC. Monitor ECG. IV. |
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boermedic
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