pharm exam #2 Word Scramble
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Question | Answer |
Antimanics are used in the treatment of | mood disorders |
Lithium is the most commonly used drug for the treatment of | mania |
Lithium is an element that is similar in chemical properties | to sodium |
Sodium is required for | conduction of nerve impulses, but lithium interferes with nerve conduction. |
Sodium range: | 135-145 |
lithium works to ____ the reuptake of NE and Dop. | increase |
Lithium takes how many weeks to fully work? | 1-2 wks |
Adequate sodium intake is necessary for proper... | urinary excretion of lith. |
therapeutic blood levels range | 0.5 to 1.5 mEq/L |
lithium maintenance dose: | 900-1200mg/day |
lithium drug interactions: | haldol, diuretics |
MOOD STABILIZERS:second best choice in the treatment of mania | are anticonvulsants |
examples of anticonvulsants: | Depakote, GABApentin, Carbamazepine |
3rd best choice: | Propranolol |
Propranolol nursing considerations | do not give if pulse is below 60 |
exogenous | reactive depression-caused by external factors death or unemployment, loss |
endogenous | caused by internal factors. Nobody ever has. Hard to diagnose. Chemical imbalance neurotransmitters. Can last for a long time. Postpartum. Get under control. |
What is the role of serotonin? | moods, arousal levels, appetite, sleep disturbances (endogenous depression) main one have to restore |
role of NE? | NE- cardiovascular system, fight or flight, moods |
Drugs that can increase the level of norepinephrine or serotonin in the brain are useful in the treatment | OF DEPRESSION |
antidepressants take | about 2 to 4 weeks to work fully in the body. |
Monoamine Oxidase Inhibitors (MAOIs) | an enzyme found in most body cells.break down norepinephrine and serotonin |
Why is this bad in relation to depression? | We need Serotonin and NE to increase |
Tyramine can produce a massive release of NE, which can result in | hypertensive crisis or cerebral stroke. |
Which foods must one avoid? | Ginseng, chocolate, beer, cheese, pickles, olives, wine and avocado |
Side effects and adverse effects of MAOI: | dry mouth, urinary ret, constipation, blurred vision, hypotension, weight gain, and sex dysfunction. can produce liver damage. |
Phenylzine (Nardil) | MAOI |
Tricyclic Antidepressants or (TCAs) | block the reuptake of norepinephrine and serotonin. |
anticholinergic sx: | dry mouth, constipation, urinary ret, tachycardia, and hypertension. |
TCAs: | Nortriptyline (Aventyl) Amitriptyline (Elavil) Doxepin (Sinequan) Imipramine (Tofranil) |
Selective Serotonin Reuptake Inhibitors (SSRIs) | block the reuptake and inactivation of serotonin in the brain. |
Sertraline (Zoloft) | dosage: 50-200mgPO |
Fluoxetine (Prozac) | dosage: 20-40mgPO |
Prozac does not mix well | anticoagulants and benzodiazepines (Xanax). |
Prozac is also effective in the treatment | OCD |
Side and Adverse effects of (SSRIs): | nausea, diarrhea, dry mouth, anorexia, and GI disturbances. |
Adverse effects OF SSRIs | 1) Weight loss 2) Insomnia 3) Tremors 4) Nervousness |
Second group of SSRIs are the atypicals. | Bupropion (Wellbutrin) & Venlafaxine (Effexor) |
atypical SSRI Duloxetine (Cymbalata) | If you have depression, diabetic neuropathy pain, fibromyalgia, generalized anxiety disorder, or chronic pain, a healthcare provider may prescribe: |
TCAs may also produce effects in | heart and liver |
TCAs are safer comapred to... | MAOIs |
Created by:
Brittneegarza
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