Pharmacology NUR300 Word Scramble
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Question | Answer |
Agonists drugs? | activate receptors, mimic actions of molecules |
Antagonists | block receptor activation |
Cholinergic receptors | mediate response to acetycholine |
Adrenergic receptors | mediate responses to epinephrine and norepinephrine |
nicotinic N | ANS ganglia |
Nicotinic M | NM junction |
muscarinic | sweat glands, blood vessels, prostate, bladder, male sex organs |
Alpha 1 | eye, skin arterioles, prostate, bladder, male sex organs |
Alpha 2 | presynaptic nerve terminals |
Beta 1 | heart, kidney |
Beta 2 | arterioles of heart, lungs, skeletal muscles, liver, uterus |
Dopaminergic | Kidney |
Muscarinic Agonists | bradycardia, sweating, salivation, bronchial secretions, constriction of bronchi, constriction of the pupil (miosis), contraction of the ciliary muscle (near vision), increase tone of GI smooth muscle, diarrhea |
Bethanecol uses? | Urinary retention not caused by blockage |
Bethanecol side effects? | diarrhea, hypotension, decrease HR, salivation, exacerbate asthma |
Pilocarpine uses? | glaucoma, dry mouth |
Pilocarpine side effects? | retinal detachment, excessive sweating |
Muscarinic antagonists | Increase HR, decrease secretion, relaxation of bronchi, constipation, pupil dilation (mydriasis) |
Atropine uses? | bradycardia, eye surgery, severe diarrhea, pathanocol overdose |
atropine side effects | dry mouth, blurred vision, increase IOP, urinary retention, constipation, anhidrosis, tachycardia, bronchial plugging in asthma |
Oxybutynin (Ditropan)uses? | overactive bladder |
Oxybutynin side effects? | puridisis, confusion |
Cholinesterase Inhibitors | blockage of the enzyme responsible for breaking down ACh, increase nicotinic effects and muscarinic effects |
Neostigmine uses? | myasthenia gravis, increase ACh in neuromuscular junctions, MUSCLE STIMULATION |
Neostigmine side effects | RESPIRATORY FAILURE, |
Edrophonium (Tensilon) uses? | diagnose MG, myasthenic crisis or cholinergic crisis |
neuromuscular blockers | block nicotinic M receptors on skeletal muscles, relaxes skeletal muscle |
Succinylcholine uses? | paralytic |
Alpha 1 | mydriasis and vasoconstriction |
Alpha 2 | CNS-reduction in sympathetic outflow to th eheart and blood vessels |
Beta 1 | increase HR, frouce of myocardial contraction, enhance impulse conduction through the AV node |
Beta 2 | promotes bronchodilation in asthma, relaxes smooth muscle in uterus |
Dopamine receptor | renal perfusion |
Epinephrine uses? | anaphylaxis, cardiac arrest, superficial bleeding, bronchodilation |
Epinephrine side effects? | hypertension, dysrhythmias, chest pain, tissue neocrosis, increase blood glucose |
Dopamine uses? | shock, heart failure, promotes cardiac and renal performance |
Alpha 1 blocking | hypotension and reduced contration of bladder smoth muscle and prostate |
Doxazosin (Cardura)/ Tamsulosin (Flomax)(-OSIN)uses? | Hypertension, BPH |
Doxazosin (Cardura)/Tamsulosin (Flomax) (-OSIN)side effects | hypotension, impotence |
Phenotolamine (Regitine) uses? | hypertension, prevention of tissue neocrosis |
Phenotolamine (Regitine) side effects? | hypotension |
Beta blockers | angina, HTN, dysrhythmias, HF, stage fright, glaucoma |
Adverse side effects of beta1 blockers | bradycardia, reduced CO, HF, rebound cardiac excitation |
Adverse side effects of beta2 blockers | bronchoconstriction, hypoglycemia |
Propanolol (-OLOL, -ILOL)uses | HTN, angina, dysrhythmias |
Propanolol side effects | bradycardia, reduced CO, HF, stage fright, glaucoma, bronchoconstriction, hypoglycemia, fatigue, impotence |
Metoprolol (Lopressor/Toprol), Atenolol (Temormin)uses? | HTN, angina, dysrhythmias |
Metoprolol (Lopressor/Toprol), Atenolol (Temormin) side effects? | bradycardia, HF, impotence, fatigue |
Centrally acting alpha 2 agonists | HTN, decrease release of NE |
Clonidine (Catapress)uses? | HTN, severe cancer pain |
Clonidine (Catapress) side effects? | impotence, nightmares, anxiety, depression, drowsiness, rebound hypertension |
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