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Connect Tiss USMLE Test

Enter the letter for the matching Answer
incorrect
1.
common present of Behcets
incorrect
2.
how is inclusion body myositis difft from polymyositis and dermatomyositis
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3.
what dz can appear like MG
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4.
clinical findings common to polymyositis and dermatomyositis
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5.
how is mscl bx different bw polymyositis and dermatomyositis
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6.
describe skin involvement in scleroderma subtypes, how relate to dz progression
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7.
what Ab + in Sjorgens
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8.
what are key distinguishing features of fibormyalgia
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9.
what hypersensit type is SLE?
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10.
describe sympt unique to diffuse scleroderma
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11.
name HLAs assoc w SLE, Sjorgen, RA, ankylosing spondylitis, Reitiers, psoriatic arthritis
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12.
CREST stands for
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13.
describe arthritis and key radiographic findings of RA
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14.
name all immunol/Ab abnml in SLE
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15.
name GN grading for SLE, which is MC and which assoc w renal failure
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16.
prophylaxis for gout, when to give, what Rx
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17.
key findings accompany RA
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18.
what dz is commonly found w Scleroderma
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19.
what type of crystals form in pseudo gout
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20.
what Ab + in mixed connective tissue dz; describe the dz
A.
SLE=DR2,3; Sjorgen=DR2; RA=DR4; ankylosing spondylitis, Reitiers, psoriatic arthritis=B27
B.
calcium pyrophosphate
C.
III
D.
more common in elderly men, prox and distal wkness, no Abs, slight incrsd CPK, poor px and response to tx
E.
symmetrical inflamm polyarthritis w hot, swollen joints, MC PIP, MCP, wrists NOT DIP; radiographic: periarticular osteoporosis, bony erosion, pannus (cartilage is like granulomatous tissue) + ulnar deviation, swan neck, and boutenierre deformities
F.
symmetrical prox mscle wknss (trbl getting up from chair, climbing steps), myalgia (1/3), dysphagia (1/3)
G.
pain is constant, aching, aggravated by stress, cold, sleep deprivation and better w rest, warmth, and mild exercise; insomnia; anxiety depression
H.
in 50% Ro (SS-A) and La (SS-B) are + [not specific]; note: SS-A at risk for neonatal SLE
I.
anti-UI-RNP; overlap of dzs but don't nec occur simultaneously
J.
give after 2 attacks, Rx: if <800mg/d urine uric acid then under secreting uric acid and give probenacid or sulfinpyrazone; if >800 then overproduction is the problem and give allopurinol
K.
Lambert-Eaton syn (in small cell lung cancer); auto Ab to presynapt Ca channels leads to decrs Ach rel; but sympt imprv w mscl use
L.
young male 20s w painful oral and genital ulcers +/- uveitis, arthritis, eryth nodosum (but no prior infxn unlike Reiters)
M.
ILD, peripheral edema, polyarteritis and carpal tunnel, fatigue, mscle involvement, + visceral involvement of lungs, heart, GI, kidney
N.
ANA, dsDNA & Sm Ab (specific), Ro & La (in ANA -, assoc neonatal SLE), anti His (Rx SLE), VDRL/RPR syph, anticardiolipin and lupus anticoag,
O.
Sjorgens (20%)
P.
C1, C2 cervical instability, pl eff common, pericarditis, episcleritis, rheum nodules
Q.
Calcinosis digits, raynauds, esophageal, sclerodactyly, telangiectasia (digits, nails)
R.
polymyositis (and inclusion body)=endomysial inflamm and fibrosis; dermatomyositis=perivascular and perimysial
S.
I=min, II=mesangial, III=focal prolifer, IV=diffuse prolifer (40%, renal failure is common), V=membranous; note: GN usu present at dx
T.
in limited only extremities and head and neck are involved (not trunk), whereas diffuse has widespread skin involvemnet; amt skin involvement can predict dz
Type the Answer that corresponds to the displayed Question.
incorrect
21.
pts who present w RA
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22.
what hypersensit type is MS? MG?
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23.
auto Ab: IgG
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24.
name the large artery vasculitis
Type the Question that corresponds to the displayed Answer.
incorrect
25.
primary biliary cirrhosis (scleroderma)
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26.
specific SLE
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27.
PAIR psoriasis, ankyl spond, inflamm bowel, Reiters
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28.
calcinosis, rayneud, esophag, sclerodactyly, telangiectesia
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29.
NSAIDs (indomethacin) and colchicine [not ASA makes worse, not acetaminophin bc doesn't have anti-inflamm prop]
incorrect
30.
beta interferon or immunosuppress

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