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Viruelence factors Test

Enter the letter for the matching Answer
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1.
Superantigens bind directly to ___ and ___. This activates ___ to release ___ and ___
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2.
S. aureus also produces enterotoxins that cause ___ and ____.
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3.
C. Botulinum produces an ___ type of exotoxin. it works by ___ and produces ____.
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4.
E. coli produces an ___ type of exotoxin. It works by ____. Produces ____.
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5.
Genes for the following 5 bacterial toxins encoded by a lysogenic phage
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6.
Bordatella pertussis produces an ____ type of exotoxin. It works by ____. Produces ___.
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7.
Location of genes for exotoxin, endotoxin
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8.
V. cholerae produces an ___ type of exotoxin. It works by ____. Produces ____.
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9.
What are organisms get resistance via transformation?
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10.
S. pyogenes produces a ____ exotoxin. This toxin is called ____ and produces ___.
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11.
S. Pyogenes produces produces an ___ type of exotoxin. it works by ___ and produces ____.
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12.
What organisms secrete IgA protease?
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13.
3 bugs that use ADP ribosylating A-B toxins are ____,____, ____, ____.
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14.
What four bacteria induce cAMP
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15.
C. diptheriae produces an ___ type of exotoxin. It works by ___. It produces ____.
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16.
Exotoxin made from ___, Endotoxin made from ____.
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17.
Superantigen of S. aureus is called ____ and produces ___ with the symptoms of ____,____, ___.
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18.
Two bugs with superantigen toxins
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19.
C. tetani produces an ___ type of exotoxin. it works by ___ and produces ____.
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20.
Protein A produced by _____.
A.
ABCDE. ShigA-like toxin, Botulinum toxin, Cholera toxin, Diptheria toxin, Erythorgenic toxin of S. pyogenes
B.
TSST-1 (toxic shock syndrome) (fever, rash, shock)
C.
C. diptheriae produces an ADP-ribosylating A-B toxin. It works by inactivating (EF-2). It causes pharyngitis and "pseudomembrane" in throat.
D.
Heat labile = stimulates adenylate cyclase. Heat stable = stimulates guanylate cyclase. ADP-ribosylating AB toxin. Both cause watery diarrhea. "Labile like the Air, stable like the Ground".
E.
ADP-ribosylating AB toxin. It works by ADP ribosylating a G protein that stimulates adenylyl cyclase; this increases the Cl into the gut and decreases Na absorption. H20 moves into the gut and causes volumninous rice water diarrhea.
F.
S. Aureus, S. pyogenes
G.
ADP-ribosylating toxin. It works by increasing cAMP by inhibiting Gi. Causes whooping caugh, inhibits chemokine receptor, causing lymphocytosis.
H.
V. cholerae, B. anthracis, E. coli (Heat labile), B. Pertussis
I.
S. aureus. Binds to Fc region of Ig, disrupting opsonization and phagocytosis.
J.
S. pneumoniae, H. influenzae, Neisseria
K.
Exotoxin=plasmid, bacteriophage, Endotoxin= bacterial chromosome
L.
S. pneumoniae, H. influenzae, Neisseria (Same as the ones that have the IgA)"Engineers get NHS grants and do major transformations"
M.
Exotoxin= polypeptide, Endotoxin =LPS
N.
Streptolysin O is a hemolysin. antigen for ASO antibody which is used in diagnosis of rheumatic fever
O.
Corynebacterium diptheriae, Vibrio cholerae, E. Coli, Bordetella pertussis.
P.
Blocks acetylcholine; causes anticholinergic symptoms, CNS paralysis, especially cranial nerves. (Spores found in food = floppy baby)
Q.
Scarlet fever-erythrogenic toxin; causes toxic shock syndrome)
R.
Blocks release of inhibitory neurotransmitters (GABA and glycine); causes lockjaw.
S.
Superantigens bind directly to MHC II and T-cell receptor simultaneously, activating large numbers of T cells to stimulate release of IFN-gamma and IL-2.
T.
Food poisoning and exfoliatin (scalded skin syndrome)
Type the Answer that corresponds to the displayed Question.
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21.
____ has vaccine available only
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22.
Pseudomonas Exotoxin is similar to ____
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23.
V. cholerae increases cAMP by ___.
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24.
Toxin is derived from a plasmid
Type the Question that corresponds to the displayed Answer.
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25.
Enzyme that cleaves IgA.
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26.
OBED (O- salmonella, Botulinum, erythrogenic toxin, Diptheria)

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