1461 General Drug Classification
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| Insulin |
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| What is the action for the PO Antidiabetic agents-Sulfonylureas,Biguanides | Increases peripheral uptake & utiization of glucose= increases the binding of insulin to its receptors & potentiate insulin action. Improves tissue sensitivity to insulin & increases glucose transport into sk.muscles & fat. Supresses glucogenesis |
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| What is the action for Antihypertensives | Centrally acting sympatholytics stimulate central alpha-adrenergic receptors, reducing cerebral sympathetic outflow, decreasing periphral vascular resistance and blood pressure. |
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| What is the action for anticoagulants | A low molecular weight heparin with antithrombotic property. Affects thrombin time & activated thromboplastin time up to 1.8 times the control value. | Lovenox= Accelerates formation of antithrombin III–thrombin complex and deactivates thrombin, preventing conversion of fibrinogen to fibrin. Drug has a higher antifactor-Xa-to-antifactor-IIa activity ratio than heparin.
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| What is the action for cardiacglycosidess | Increases the force and velocity of myocardial systolic contractions (positive inotropic effect). Also decreases conduction velocity through the AV node |
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| What is the action for Diuretics | Inhibits reabsorption of sodium and chloride in the proximal and distal tubules and in the loop of henle. |
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| What is the action for Corticosteroids | There are 2 sub-groups= (Glucocorticoids) regulates the metabolic pathways involving protein,carbs,& fat. (mineralocorticoids)involved in electrolyte & water balance. |
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| What is the action for Opioid Analgesics | Acts as an agonist at specific opioid-receptors binding sites in the CNS and other tissues, altering the pt's perception of pain. |
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| What is the action for Bronchodilators | albuterol= Relaxes bronchial, uterine, and vascular smooth muscle by stimulating beta2 receptors.
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| What is the action for NSAIDS | . | IBU= May inhibit prostaglandin synthesis, to produce anti-inflammatory, analgesic, and antipyretic effects.
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| What is the action for Gastric Acid Pump Inhibitors | . | Protonix= Inhibits proton pump activity by binding to hydrogen-potassium adenosine triphosphatase, located at secretory surface of gastric parietal cells, to suppress gastric acid secretion.
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| What is the MOA for Antiemetics | . | Zofran= May block 5-HT3 in the CNS in the chemoreceptor trigger zone and in the peripheral nervous system on nerve terminals of the vagus nerve.
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| What is the MOA for Laxatives | . | surfak= Stool softener that reduces surface tension of interfacing liquid contents of the bowel. This detergent activity promotes incorporation of additional liquid into stools, thus forming a softer mass.
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| What is the MOA for Antipyretics | . | Tylenol= Thought to produce analgesia by inhibiting prostaglandin and other substances that sensitize pain receptors. Drug may relieve fever through central action in the hypothalamic heat-regulating center.
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| What is the MOA for Antibiotics | . | Levaquin= Inhibits bacterial DNA gyrase and prevents DNA replication, transcription, repair, and recombination in susceptible bacteria
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| What is the MOA for Anticonvulsants | . | Dilantin= May stabilize neuronal membranes and limit seizure activity either by increasing efflux or decreasing influx of sodium ions across cell membranes in the motor cortex during generation of nerve impulses.
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