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ACC-1461 Drugs

1461 General Drug Classification

QuestionAnswer
Insulin
What is the action for the PO Antidiabetic agents-Sulfonylureas,Biguanides Increases peripheral uptake & utiization of glucose= increases the binding of insulin to its receptors & potentiate insulin action. Improves tissue sensitivity to insulin & increases glucose transport into sk.muscles & fat. Supresses glucogenesis
What is the action for Antihypertensives Centrally acting sympatholytics stimulate central alpha-adrenergic receptors, reducing cerebral sympathetic outflow, decreasing periphral vascular resistance and blood pressure.
What is the action for anticoagulants A low molecular weight heparin with antithrombotic property. Affects thrombin time & activated thromboplastin time up to 1.8 times the control value. Lovenox= Accelerates formation of antithrombin III–thrombin complex and deactivates thrombin, preventing conversion of fibrinogen to fibrin. Drug has a higher antifactor-Xa-to-antifactor-IIa activity ratio than heparin.
What is the action for cardiacglycosidess Increases the force and velocity of myocardial systolic contractions (positive inotropic effect). Also decreases conduction velocity through the AV node
What is the action for Diuretics Inhibits reabsorption of sodium and chloride in the proximal and distal tubules and in the loop of henle.
What is the action for Corticosteroids There are 2 sub-groups= (Glucocorticoids) regulates the metabolic pathways involving protein,carbs,& fat. (mineralocorticoids)involved in electrolyte & water balance.
What is the action for Opioid Analgesics Acts as an agonist at specific opioid-receptors binding sites in the CNS and other tissues, altering the pt's perception of pain.
What is the action for Bronchodilators albuterol= Relaxes bronchial, uterine, and vascular smooth muscle by stimulating beta2 receptors.
What is the action for NSAIDS . IBU= May inhibit prostaglandin synthesis, to produce anti-inflammatory, analgesic, and antipyretic effects.
What is the action for Gastric Acid Pump Inhibitors . Protonix= Inhibits proton pump activity by binding to hydrogen-potassium adenosine triphosphatase, located at secretory surface of gastric parietal cells, to suppress gastric acid secretion.
What is the MOA for Antiemetics . Zofran= May block 5-HT3 in the CNS in the chemoreceptor trigger zone and in the peripheral nervous system on nerve terminals of the vagus nerve.
What is the MOA for Laxatives . surfak= Stool softener that reduces surface tension of interfacing liquid contents of the bowel. This detergent activity promotes incorporation of additional liquid into stools, thus forming a softer mass.
What is the MOA for Antipyretics . Tylenol= Thought to produce analgesia by inhibiting prostaglandin and other substances that sensitize pain receptors. Drug may relieve fever through central action in the hypothalamic heat-regulating center.
What is the MOA for Antibiotics . Levaquin= Inhibits bacterial DNA gyrase and prevents DNA replication, transcription, repair, and recombination in susceptible bacteria
What is the MOA for Anticonvulsants . Dilantin= May stabilize neuronal membranes and limit seizure activity either by increasing efflux or decreasing influx of sodium ions across cell membranes in the motor cortex during generation of nerve impulses.
Created by: monica_acc