lorazepam
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Ativan's generic/chemical name | lorazepam
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Ativan is an | anxiolytic, benzodiazepine
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lorazepam adult dose | PO 2-6 mg/d with max of 10 mg/d
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Ativan contraindication 1 | hypersensitivity
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Ativan contraindication 2 | CNS depression
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Ativan contraindication 3 | shock
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Ativan contraindication 4 | coma
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Ativan contraindication 5 | narrow-angle glaucoma
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Ativan contraindication 6 | pregnancy & lactation
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lorazepam food drug 1 | increases CNS depression when taken w/alcohol
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lorazepam food drug interactions 2 | CNS depression
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lorazepam food drug interactions 3 | anticonvulsants
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lorazepam food drug interactions 4 | cimetidine increase plasma levels of drug
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lorazepam food drug interactions 5 | increase phenoytoin levels
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lorazepam food drug interactions 6 | decrease *levodopa effects
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lorazepam food drug interactions 7 | Smoking decreases antianxiety effects
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Ativan and Kava Kava may | potentiate sedation
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lorazepam is absorbed | rapidly in GI tract
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PB | 85%
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t 1/2 | 12-14 h
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lorazepam is excreted | urine
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Ativan onset | UK
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Ativan peak | 2 h
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lorazepam duration | 12-24 h
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Ativan's 3 therapeutic effects | 1. control anxiety. 2.treat *status epilepticus. 3.preoperative sedation
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lorazepam's mode of action | potentiate gamma-aminobutyric (GABA) effects by binding to specific benzodiazepine receptors and INHIBITING GABA neurotransmission
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Side effects of Ativan | drowsiness, dizziness, weakness, confusion, blurred visin, nausea, vomiting, anorexia, sleep disturbance, restlessness, hallucinations.
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Adverse reactions of lorazepam | hypertension, hypotension
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Nursing assessment 1 | assess for suicidal ideation
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Nursing assessment 2 | Obtain hx of client's anxiety reaction
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Nursing assessment 3 | Determine client's support system
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Nursing assessment 4 | obtain drug hx, report possible drug-drug interactions
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Possible nursing diagnoses | 1.Anxiety r/t panic. 2.Impared physical mobility r/t drowsiness and weakness.
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Nursing Intervention 1 | Observe client for side effects of anxiolytics. Recognize drug tolerance, physical, psychological dependency can occur.
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Nursing Intervention 2 | anxiolytic dosages should be lower for older adults, children, debilitated persons
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Nursing Intervention 3 | monitor VS, especially B/P and pulse. Ortostatic hypotension.
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Nursing Intervention 4 | encourage family to be supportive of client
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General teaching 1 | advise pt not to drive while taking anxiolytics
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General teaching 2 | instruct pt not to consume alcohol
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General teaching 3 | teach pt to control excess stress & anxiety
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General teaching 4 | encourage pt to follow drug regimen and not to abruptly stop taking the drug after prolonged use b/c withdrawl symtoms can occur- dose is usually tappered.
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Side effects | orthostatic hypotension & dizziness; teach pt to rise slowly from sitting to standing
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