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Ativan's generic/chemical name lorazepam
Ativan is an anxiolytic, benzodiazepine
lorazepam adult dose PO 2-6 mg/d with max of 10 mg/d
Ativan contraindication 1 hypersensitivity
Ativan contraindication 2 CNS depression
Ativan contraindication 3 shock
Ativan contraindication 4 coma
Ativan contraindication 5 narrow-angle glaucoma
Ativan contraindication 6 pregnancy & lactation
lorazepam food drug 1 increases CNS depression when taken w/alcohol
lorazepam food drug interactions 2 CNS depression
lorazepam food drug interactions 3 anticonvulsants
lorazepam food drug interactions 4 cimetidine increase plasma levels of drug
lorazepam food drug interactions 5 increase phenoytoin levels
lorazepam food drug interactions 6 decrease *levodopa effects
lorazepam food drug interactions 7 Smoking decreases antianxiety effects
Ativan and Kava Kava may potentiate sedation
lorazepam is absorbed rapidly in GI tract
PB 85%
t 1/2 12-14 h
lorazepam is excreted urine
Ativan onset UK
Ativan peak 2 h
lorazepam duration 12-24 h
Ativan's 3 therapeutic effects 1. control anxiety. 2.treat *status epilepticus. 3.preoperative sedation
lorazepam's mode of action potentiate gamma-aminobutyric (GABA) effects by binding to specific benzodiazepine receptors and INHIBITING GABA neurotransmission
Side effects of Ativan drowsiness, dizziness, weakness, confusion, blurred visin, nausea, vomiting, anorexia, sleep disturbance, restlessness, hallucinations.
Adverse reactions of lorazepam hypertension, hypotension
Nursing assessment 1 assess for suicidal ideation
Nursing assessment 2 Obtain hx of client's anxiety reaction
Nursing assessment 3 Determine client's support system
Nursing assessment 4 obtain drug hx, report possible drug-drug interactions
Possible nursing diagnoses 1.Anxiety r/t panic. 2.Impared physical mobility r/t drowsiness and weakness.
Nursing Intervention 1 Observe client for side effects of anxiolytics. Recognize drug tolerance, physical, psychological dependency can occur.
Nursing Intervention 2 anxiolytic dosages should be lower for older adults, children, debilitated persons
Nursing Intervention 3 monitor VS, especially B/P and pulse. Ortostatic hypotension.
Nursing Intervention 4 encourage family to be supportive of client
General teaching 1 advise pt not to drive while taking anxiolytics
General teaching 2 instruct pt not to consume alcohol
General teaching 3 teach pt to control excess stress & anxiety
General teaching 4 encourage pt to follow drug regimen and not to abruptly stop taking the drug after prolonged use b/c withdrawl symtoms can occur- dose is usually tappered.
Side effects orthostatic hypotension & dizziness; teach pt to rise slowly from sitting to standing
Created by: starz_1_girl