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Ativan
lorazepam
| Question | Answer |
|---|---|
| Ativan's generic/chemical name | lorazepam |
| Ativan is an | anxiolytic, benzodiazepine |
| lorazepam adult dose | PO 2-6 mg/d with max of 10 mg/d |
| Ativan contraindication 1 | hypersensitivity |
| Ativan contraindication 2 | CNS depression |
| Ativan contraindication 3 | shock |
| Ativan contraindication 4 | coma |
| Ativan contraindication 5 | narrow-angle glaucoma |
| Ativan contraindication 6 | pregnancy & lactation |
| lorazepam food drug 1 | increases CNS depression when taken w/alcohol |
| lorazepam food drug interactions 2 | CNS depression |
| lorazepam food drug interactions 3 | anticonvulsants |
| lorazepam food drug interactions 4 | cimetidine increase plasma levels of drug |
| lorazepam food drug interactions 5 | increase phenoytoin levels |
| lorazepam food drug interactions 6 | decrease *levodopa effects |
| lorazepam food drug interactions 7 | Smoking decreases antianxiety effects |
| Ativan and Kava Kava may | potentiate sedation |
| lorazepam is absorbed | rapidly in GI tract |
| PB | 85% |
| t 1/2 | 12-14 h |
| lorazepam is excreted | urine |
| Ativan onset | UK |
| Ativan peak | 2 h |
| lorazepam duration | 12-24 h |
| Ativan's 3 therapeutic effects | 1. control anxiety. 2.treat *status epilepticus. 3.preoperative sedation |
| lorazepam's mode of action | potentiate gamma-aminobutyric (GABA) effects by binding to specific benzodiazepine receptors and INHIBITING GABA neurotransmission |
| Side effects of Ativan | drowsiness, dizziness, weakness, confusion, blurred visin, nausea, vomiting, anorexia, sleep disturbance, restlessness, hallucinations. |
| Adverse reactions of lorazepam | hypertension, hypotension |
| Nursing assessment 1 | assess for suicidal ideation |
| Nursing assessment 2 | Obtain hx of client's anxiety reaction |
| Nursing assessment 3 | Determine client's support system |
| Nursing assessment 4 | obtain drug hx, report possible drug-drug interactions |
| Possible nursing diagnoses | 1.Anxiety r/t panic. 2.Impared physical mobility r/t drowsiness and weakness. |
| Nursing Intervention 1 | Observe client for side effects of anxiolytics. Recognize drug tolerance, physical, psychological dependency can occur. |
| Nursing Intervention 2 | anxiolytic dosages should be lower for older adults, children, debilitated persons |
| Nursing Intervention 3 | monitor VS, especially B/P and pulse. Ortostatic hypotension. |
| Nursing Intervention 4 | encourage family to be supportive of client |
| General teaching 1 | advise pt not to drive while taking anxiolytics |
| General teaching 2 | instruct pt not to consume alcohol |
| General teaching 3 | teach pt to control excess stress & anxiety |
| General teaching 4 | encourage pt to follow drug regimen and not to abruptly stop taking the drug after prolonged use b/c withdrawl symtoms can occur- dose is usually tappered. |
| Side effects | orthostatic hypotension & dizziness; teach pt to rise slowly from sitting to standing |
Created by:
starz_1_girl
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