Pharm Ch 75 Asthma drug drill
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| we only use a spacer on this type of delivery | only with MDI medtered dose inhalers
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| 2 classes that are preventative bwo anti-inflammation MOA | glucocorticosteroids----non-steroidal anti-inflammatory
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| What class of drugs is effetive for both anti-inflammation (prevention) and acute attacks | Beta-2 agonists
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| what class is most effective for prevention | glucocorticosteroids - but not for acute
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| which class is safest, also where we generally start kids | non-steroidal anti-inflamms
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| what class is less effective than, but also used in conjunction with B-2 agonists for difficult to control patients | anticholinergics - they block normal bronchoCON resulting in bronchDIL
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| name 4 inhaled 'sone steroidals | beclomethasone --- flucticasone ---mometesone ---triamcinalone
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| beclomethasone | inhaled 'sone steroid anti-inflamm most effective prevention class
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| fluticasone | inhaled 'sone steroid anti-inflamm most effective prevention class
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| mometasone | inhaled 'sone steroid anti-inflamm most effective prevention class
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| triamcinolone | inhaled 'sone steroid anti-inflamm most effective prevention class
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| name 3 inhaled 'ide steroids | budenoside --- ciclenoside --- flunisolide
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| budenoside | inhaled 'ide steroid anti-inflamm most effective prevention class
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| ciclenoside | inhaled 'ide steroid anti-inflamm most effective prevention class
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| flunisolide | inhaled 'ide steroid anti-inflamm most effective prevention class
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| name 4 oral/systemic steroids-antiinflamm | prednisone --- prednisolone---methylpredisolone---dexamethasone
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| of the 4 oral/systemic steroids, which are also IV admin for most acute cases | methylprednisolone---dexamethasone
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| pt education for inhaled steroids | must gargle after use and use spacer to increase drug delivery and minimize SEs
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| name 2 drugs in saftest of all class - NSAIDs for asthma | cromolyn---nedocromil
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| cromolyn class | NSAID-asthma-safest-kids
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| nedocromil class | NSAID-asthma-safest-kids
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| Name 4 beta agonists - used both for prevention and acute - that are inhaled/quick/short | albuterol---levalbuterol---bitolterol---pirbuterol
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| albuterol | quick/short inhaled Beta -2 agonist
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| levalbuterol | quick/short inhaled Beta -2 agonist
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| bitolterol | quick/short inhaled Beta -2 agonist
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| pirbuterol | quick/short inhaled Beta -2 agonist
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| name 3 beta agonists - used for prevention and acute - inhaled/long acting | salmeterol---formoterol---alformoterol
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| salmeterol | inhaled/long acting/ Beta-2 agonist
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| formoterol | inhaled/long acting/ Beta-2 agonist
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| alformoterol | inhaled/long acting/ Beta-2 agonist
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| name 2 rarely used oral B-2 agonists acute/prevention | albuterol---terbutaline
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| albuterol - other admin | also oral, rarely used, B-2 agonist
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| terbutaline | oral, rarely lused B-2 agonist
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| Name 2 anticholinergics usually used for additive effect with B-2 agonist (MDI/nebulizer) | ipratropium --- tiotoprium
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| ipratropium | anticholinergic
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| titoproprium | longer-acting anticholinergic
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| name 1 methylxanthine with very narrow TI | theophylline -- also with CNS/CV SEs. rarely used
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| name 1 leukotriene modifier | montelukast
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