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Thought Disorders

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Answer
What is delirium?   A rapid change in consciousness that occurs over a short time. Reversible.  
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List four causes of delirium:   *Hypoxia *Electrolyte imbalances *Drugs *Pain *Fatigue *Infections  
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List four S/Sx of delirium:   *Disorientation *Overwhelming anxiety *Tremors *Florid (elaborate/flamboyant) delusions *Illusions and/or hallucinations *Disturbed psychomotor activity *Sleep-wake cycles *Incoherence  
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What is Sun-downing syndrome?   *Nocturnal delirium *Displays increased disorientation and agitation only during the evening or nighttime  
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What is the most common form of dementia?   Alzheimers  
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What are delusions?   A fixed, false belief that cannot be corrected by feedback and is not accepted as true by others in the culture  
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Give an example of delusional ideas of reference.   Thinking someone on TV took your idea  
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Give an example of Somatic Delusions.   Person thinking they have an illness with no proof  
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Give an example of delusional thought broadcasting   “You know what I am thinking”  
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Give an example of delusional Thought Insertion   “She put these thoughts in my head”  
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Give an example of delusional Thought Withdrawal   “You have been stealing my thoughts!”  
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What complications and enviromental factors during pregnancy can increase the chances of child being schizophrenic?   *Birth trauma *Mother contracting a virus like the flu, especially in 2nd trimester *Winter birth  
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What are the structural brain abnormalities in people with schizophrenia?   *Enlarged lateral and third ventricles *Enlarged sulci *Brain atrophy *Hypofrontality (reduced activation in the frontal cortex)  
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How does dopamine relate to schizophrenia?   *Excess of Dopamine in the center of the brain *Lowered Dopamine levels in the prefrontal cortex region  
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What does the schizophrenia vulnerability model propose?   that each of us is endowed with a degree of vulnerability that under suitable circumstances will express itself in an episode of schizophrenic illness  
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What is Alogia?   reduced content of speech  
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What is Anhedonia?   inablity to experience pleasure  
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What is Avolition?   lack of initiative/motivation  
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What are the S/Sx of schizophrenia?   *Alogia *Anhedonia *Avolition *Attentional impairment *Affective flattening *Hallucinations *Delusions *Formal thought disorder *Repeated instances of bizarre or disorganized behavior  
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What are the four stages of schizophrenia?   *Prodromal Phase: Begins with lack of energy or motivation *Prepsychotic Phase: Presents with desire to be left alone *Acute Phase: S/Sx vary; lose contact with reality *Residual Phase: Symptoms resemble prodromal phase  
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What are the antipsychotic (neuroleptic) drugs used in Tx of schizophrenia?   *Clozapine *Risperidone *Olanzapine *Sertindol *Ziprasidone *Quetiapine  
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What blood disorder can clozapine cause?   Agranulocytosis  
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How will antipsychotic medications affect epileptics?   It lowers the seizure threshold (Increasing chances of seizure) so anti-seizure medications may need increased doses  
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What is Neuroleptic Malignant Syndrome?   *An extreme adverse reaction to antipsychotic drugs characterized by; *Rigidity with high fever *Water intoxication: Polydipsia with hyponatremia (life threatening)  
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What is Acute Extrapyramidal Syndrome?   *An adverse raction to antipsychotic drugs *Dystonia: thick/protruding tongue, stiff neck, abnormal posture of upper limbs *Parkinson like symptoms *Akathisia: extreme restlessness/inability to sit still w/increased motor activity  
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What are the medications used to manage extrapyramidal side effects?   *Cogentin *Artane *Symmetril  
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What is the evidence to support the genetic basis of schizophrenia?   First degree relatives are 10 times more likely to develop schizophrenia than the general population  
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Clozapine (Clozaril) is used only for schizophrenic PTs who are what?   unresponsive to other antipsychotic drugs  
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Chlorpromazine (Thorazine) is used to treat what in addition to schizophrenia?   Uncontrolled hiccups  
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What is Tardive Dyskinesia?   *Antipsychotic side effect *Rhythmic, involuntary movements of tongue, face, mouth or jaw *Tongue may protrude and there may be chewing movements, puckering of the mouth and facial grimacing  
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How often must PTs on antipsychotics be monitored for onset of akathisia, extrapyramidal, parkinsonian, and dystonia?   every two months during therapy and 8-12 weeks after therapy has been discontinued  
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What must you do with a schizophrenic patient after administering parenteral neuroleptics?   Keep patient recumbent for at least 30 minutes following parenteral administration to minimize hypotensive effects  
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How are PO neuroleptic medications to be administered?   with food, milk, or a full glass of water to minimize gastric irritation  
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PO neuroleptic medication concentrates must be diluted in what?   120mL distilled or acidified water, or fruit juice  
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