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Exam 2

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
What are the cardinal signs of inflammation?   redness, swelling, heat, pain, and functional impairment  
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Define swelling.   water in the interstitial space  
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Fast fibers are also called ________ and they react ____________.   A-fibers; instantaneously  
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Slow fibers are also called _________ and they _______________.   C-fibers; send signals when neighbors are injured  
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What is vasodilation controlled by?   histamine  
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Parenchymal cells   contain functioning cells of organ or body part  
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Stromal cells   contain supporting connective tissues, blood vessels, and nerve fibers  
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Labile cells   continue to regenerate, such as skin  
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Stable cells   normally stop regenerating, such as the liver  
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Permanent or fixed cells   cannot regenerate, replaced with fibrous scar tissue, such as nerve, skeletal and cardiac muscle cells  
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Is there tissue loss in primary intention (1st) healing?   no tissue loss  
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Is there tissue loss in secondary (2nd) intention healing?   yes, there is tissue loss  
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What are the three phases of healing?   inflammatory, proliferative, and remodeling  
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During the proliferative phase of healing, what cell is being used and what is it responsible for?   fibroblast; collagen and angiogenesis  
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What are the three layers of the heart?   pericardium, myocardium, and endocardium  
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What are the two layers of the pericardium?   parietal and visceral  
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How many liters of blood are in a 70 kilo person?   5 liters  
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What is the MAP in the arteries?   90-100 mm/Hg  
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What is the MAP in the small arteries?   60-90 mm/Hg  
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What is the MAP in the arterioles?   40-60 mm/Hg  
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What is the MAP in the capillaries?   26-32 mm/Hg  
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What is the MAP in the veins?   0-10 mm/Hg  
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What is the formula to calculate cardiac output (CO)?   heart rate times stroke volume (HR x SV)  
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What is cardiac output (CO)?   the amount of blood ejected from the left ventricle in the aorta in one minute  
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What is the normal cardiac output (CO) in a 70 kilo person?   5,040cc/min  
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What is stroke volume (SV)?   the amount of blood ejected from the left ventricle in one beat  
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What is the formula to calculate stroke volume (SV)?   endiostolic volume minus ensystolic volume (EDV-ESV)  
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What is endiostolic volume (EDV)?   the amount of blood in the left ventricle at the end of diastole  
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What is ensystolic volume (ESV)?   the amount of blood in the left ventricle at the end of systole  
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What is normal stroke volume (SV) in a 70 kilo person?   70cc/beat  
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What is the formula to calculate ejection fraction (EF)?   stroke volume divided by endiostolic volume (SV÷EDV)  
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What is ejection fraction (EF)?   the percentage of blood that was in the left ventricle at the end of systole that was ejected into the aorta  
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What is a normal ejection fraction (EF)?   65-85%  
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What two things affect endiostolic volume (EDV)?   cardiac preload and myocardial distensibility  
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What two things affect ensystolic volume (ESV)?   cardiac afterload and myocardial contractility  
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What is cardiac preload?   volume of blood in left ventricle at the end of diastole  
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What is cardiac afterload?   resistance to ejection from the chamber of the heart (left ventricle)  
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What is myocardial contractility?   speed and force of contraction  
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What is myocardial distensibility?   willingness of myocardium to stretch  
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What influences myocardial distensibility the most?   oxygen status (ATP status)  
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