Vocabulary
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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Tardative dyskinsia | Involuntary movement of jaw - call doctor immediately or could become permanent
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CTZ | Chemoreceptor trigger zone
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Serotonin Agents | Ondanestron (Zofran)
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Serotonin Action | Blocks the serotonin receptor in our brain that makes us feel nauseous when it's stimulated
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Metoclopramide (Reglan) | Dopamine & Prokinetic
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Dopamine Antagonists | Prochlorperazine (Compazine)
Promethazine (Phenergan)
Metoclopramide (Reglan)
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Dopamine Action | Blocks the dopamin receptor in our brain that makes us feel nauseous when it's stimulated
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Ondanestron | Zofran
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Metoclopramide | Reglan
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Promethazine | Phenergan
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Prochlorperazine | Compazine
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Prokinetic | Metoclopramide (Reglan)
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Prokinetic Action | Dopamine blocker
Increase tone of lower esophageal sphincter
Increase peristalsis
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Serotonin Admin | PO 30 - 40 mins. before Surgery or expected nausea
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Serotonin Indications | Nausea r/t pregnancy, chemo, cancer
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Serotonin Side Effects | Headache, Dizziness, Diarrhea
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Serotonin Teaching | No driving bc sedation
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Dopamine Indications | Prevents Nausea
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Dopamine Admin | PO, IV (slow-over 15 mins.), Rectal, No IV Push
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Dopamine Side Effects | Muscle spasms, tremors, rigidity
Hypotension
Sedation
Dry mouth, urinary retention, constipation
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Dopamine Teaching | Encourage fluids
Make Pt. aware of side effects
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Prokinetic Indications | Nausea, Vomitting, Pt's w/reflux (moves things through quickly)
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Prokinetic Admin | IV or PO, usually 30 mins before meals
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Prokinetic Side Effects | Sedation, diarrhea, dry mouth, Tardative dyskinesia
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Prokinetic Teaching | No alcohol or driving bc of sedation
Monitor BP & hypotension
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Antihistamines | Dimenhydrinate (Dramamine)
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Dimenhydrinate | Dramamine
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Antihistamine Action | Blocks histamine receptors in the inner ear and CTZ - Prevents Motion Sickness
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Antihistamine Indications | Motion sickness
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Antihistamine Admin | PO, IV, IM, Rectal
Give 30 mins prior to activity that causes sickness
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Antihistamine Side Effects | Sedation, Drowsiness, Dizziness, Dry mouth, constipation, Urinary retention
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Antihistamine Teaching | Teach about side effects
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Antiemetics | Seotonin Antagonists
Dopamine Antagonists
Prokinetic
Antihistamines
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Seotonin Antagonists Dopamine Antagonists Prokinetic Antihistamines | Antiemetics
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Histamine2 Receptor Agents | Cimetidine (Tagamet)
Famotidine (Pepcid)
Ranitidine (Zantac)
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Histamine2 Receptor Agents Action | Block histamine receptors in stomach to decrease acid in stomach
(doesn't prevent reflux but increases pH)
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Histamine2 Receptor Agents Indications | Reflux, Gastic & duodenum ulcers
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Histamine2 Receptor Agents Admin | Admin w/or w/o food, don't admin antacids w/in 1 hr. of giving antagonist (effects absorption rate)
IV must be given slowly or can cause bradycardia
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Histamine2 Receptor Agents Side Effects | Nausea, vomiting, diarrhea, constipation
Decreased WBC's (long term use)
Tagamet: Seizures, Lower labido, Lethargy
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Histamine2 Receptor Agents Teaching | Antacids affect absorption rate of Antagonist, Smoking also interferes with absorption
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Cimetidine | Tagamet
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Ranitidine | Zantac
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Famotidine | Pepcid
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Proton Pump Inhibitors (PPIs) | Omeprazole (Prilosec)
Lansoprazole (Prevacid)
Pantoprazole (Protonix)
Esomeprazole (Nexium)
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PPI Action | Decreases the acids in the stomach
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PPI Indications | Reflux, duodenum & gastic ulcers
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PPI Admin | Empty stomach, usually 1x daily before breakfast
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PPI Side Effects | Nausea, vomiting, diarrhea
Long term use = bone loss
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PPI Teaching | Antacids do not affect absorption
^ Vit D
^ Ca+
^ Exercise
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Omeprazole | Prilosec
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Lansoprazole | Prevacid
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Pantoprazole | Protonix
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Esomeprazole | Nexium
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Mucosal Protectants | Sucralfate (Carafate)
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Sucralfate | Carafate
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Mucosal Protectants Action | Creates gel to coat stomach (good w/pt's already have ulcer)
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Mucosal Protectants Indications | Pt.'s w/ Ulcers
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Mucosal Protectants Admin | Empty stomach - wait 2hrs before/after meals or other meds - affects absorption
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Mucosal Protectants Side Effects | Constipation, nausea, diarrhea, dyspepsia
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Mucosal Protectants Teaching | Teach pt how to take
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Antacids | Aluminum hydroxide (Amphojel)
Calcium carbonate (Tums)
Magnesium hydroxide (Milk of Magnesia)
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Aluminum hydroxide | Amphojel
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Calcium carbonate | Tums
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Magnesium hydroxide | Milk of Magnesia
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Aluminum hydroxide Action | Neutralize gastric acid
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Aluminum hydroxide Indications | Ulcers and reflux
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Aluminum hydroxide Admin | PO
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Aluminum hydroxide Side Effects | Amphojel & Tums: Constipation
Milk of Magnesia: Diarrhea
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Aluminum hydroxide Teaching | Know what other medications are being taken
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Decreased Blood flow + Increased stomach acid = | Perfect environment for an ulcer
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Prostaglandin E Analogs | Misoprostol (Cytotec)
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Misoprostol | Cytotec
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Prostaglandin E Analogs Action | Works to increase pH, protect against ulcer, allow adequate blood flow to the gastric wall
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Prostaglandin E Analogs Indications | Prevents gastric ulcers from long-term NSAID use
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Prostaglandin E Analogs Admin | Take w/meals while taking NSAID
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Prostaglandin E Analogs Side Effects | Diarrhea, Ab pain, nausea
Women: uterine cramps, spotting
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Prostaglandin E Analogs Teaching | Do not take if pregnant - spontaneous abortion
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What drug can cause a spontaneous abortion in women if taken during pregnancy? | Misoprostol
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Cancer of Oral Cavity Risk Factors | Alcohol/smoking
Greater in Males >50yrs
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Cancer of Oral Cavity Pathophysiology | Lips, Tongue, Floor of mouth
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Cancer of Oral Cavity Clin. Manifestations | Painless lesion that doesn't heal
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Cancer of Oral Cavity Diagnostic Tests | Biopsy to confirm
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Cancer of Oral Cavity Treatment | Depends on type/extent
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Cancer of Oral Cavity #1 concern | Airway
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A stroke is the | 3rd leading cause of death in USA
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Up to 80% of strokes are | preventable
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Strokes are the leading cause of | long-term disability
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_______ are more likely to have a stroke. | Men
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_______ are more likely to die from a stroke. | Women
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Cerebrovascular Disorder | Any interruption of blood supply to brain causing CNS Functional abnormality
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Stroke | O2 supply to the brain is disrupted
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Stroke has 4x higher incidence in | left hemi-sphere
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"STR" | Can a person... Speak simple sentence?
Talk?
Raise both arms?
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"F A S T" | Facial
Arms
Speech
Time
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Neuroplasticity | Neuron's ability to rearrange connections
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Brain adaption | brain saturated w/blood or deprived of O2 = find alt. pathways
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Transient Ishemic Attack (TIA's) | Cerebral ischemic event lasting < 24 hrs
May even last just a few minutes
No permanent neurological chgs.
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Evolving Stroke | Worsening of deficits over minutes
Suggests widening area of ischemia
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Completed Stroke | Acute cerebral ischemic event w/deficits
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#1 risk factor for stroke | Hypertension
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TIA aka | "warning strokes"
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Blood clot temporarily clogs artery so part of brain doesn't get blood it needs | TIA
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S/S of TIA | Similar to stroke, usually last 1 or 2 mins.
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Ischemic Stroke | Obstruction of cerebral blood flow
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88% of all strokes are | Ischemic Stroke
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"Worst headache of my life" | Subarachnoid hemorrhage
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Receptive Aphasia | Person doesn't know what's going on
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Expressive Aphasia | Person knows what's going on, but can't express
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Broca's Area located in | Left hemisphere
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Controls tongue, lips, vocal cords & ability to phonate (form words) | Broca's Area
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Global Aphasia | Expressive & receptive aphasia
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Dysphagia | Difficulty swallowing
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Dysarthia | Impaired speech
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Ataxia | Gait disturbance
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Nystagmus | Rapid Eye Movements
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Hemianesthesia | Pain on one half of body that doesn't completely register
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Wernicke's Area | Can be in whichever hemisphere is dominant for pt.
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Recalls, recognizes & interprets words & other sounds in the process of "phonating" | Wernicke's Area
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Dmg. to Wernicke's Area (Temporal lobe of dominant hemisphere) | Inability to comprehend spoken or written words
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If a Pt. is newly diagnosed with Afib, do TEE test to see if | There are clots behind the heart
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Trans-esophageal echocardiogram | TEE test
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Tissue Plasminogen Activator (tPA) | Time of onset is known and < 3 hrs
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Pt not a candidate for tPA if | Pt is rcvg IV Heparin
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Angioplasty | Any endovascular procedure to reopen narrowed blood vessels & restore forward blood flow
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Atherectomy | Opens occluded, scarred or calcified vessels by removing atherosclerotic plaques with rapidly rotating drills
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Balloon angioplasty | Relies on the inflation of high-pressure balloons within blocked arteries to force open
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Laser & radiofrequency waves | Vaporize or ablate atheroscleroptic plaques
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Endovascular stents | Hold vessels open with expandable lattices inserted across narrowed section of the artery
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Cerebral Angioplasty | Coils surgically placed in cerebral vascular malformations to assure patency and prevent rupture (Aneurysm)
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Hemorrhagic Strokes | Vessel ruptures & bleeds into brain or spaces around brain
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Intracerebral Hemorrhage | Always hypertension related
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Craniectomy | Removal of part of the brain
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Craniotomy | Redirection - keep from getting to brain stem
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Subarachnoid Hemorrhage | Bleeding into subarachnoid space
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Arteriovenous Malformation | A tangle of blood vessels in the brain or on the surface of brain that bypasses norm brain tissue and diverts blood from arteries to the veins
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Mandibular Fractures Clin. Manifestations | Dull ache -> throbbing pain
Restricted jaw movement
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Mandibular Fractures Diagnostic | X-ray or MRI
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Mandibular Fractures Treatment | Rigid plate fixation
Bone grafting
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Mandibular Fractures Nurse Mngmnt. | #1 Airway
#2 Nutrition
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Absent/ineffective peristalsis of distal esophagus Failure of esophageal sphincter to relax in response to swallowing | Achalasia
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Achalasia | Food cannot get into the stomach
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Achalasia Diet | Small frequent meals/soft/encourage fluids
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Achalasia Meds | Ca+ channel blockers relax sphincters
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Achalasia Pneumatic dilation | Balloon to try and open sphincter up
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Achalasia Esophagomyotomy | Enter esophagus & cut muscle fibers
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90% of Hiatal Hernias are | Sliding esophageal hernias
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sliding Hernia Manifestations | Heartburn
Regurgitation
Dysphasia
Belching
Reflux*
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Reflux Occurs w/sliding hernia because | Sphincter is NOT intact - food easily regurgitates into esophagus.
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Paraesophageal manifestations | Sense of fullness after eating
Indigestion
May be a symptomatic
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The sphincter in a paraesophageal hernia | Is still intact.
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Hiatal hernia complications | Strangulation
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Gastroesophageal Reflux Disease (GERD) | Backflow of gastric contents into esophagus
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Avoid these if you have GERD | High-fat diet
Caffeine, tobacco, alcohol, spearmint, peppermint, carbonated bevs
Eating 2 hrs before bed
Tight clothing
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Meds for GERD | Antacids
Histamine Receptor Blockers
PPIs
Prokinetic Agents
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Treatment of GERD | Nissen fundoplication
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Nissen fundoplication | Surgery to wrap stomach around esophagus = No reflux
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Barrett's Esophagus | Chgs cells in esophagus bc constant burning of lining from reflux -> pre-cancerous condition
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S/S Barrett's Esophagus | Same as GERD -> ppl usually don't know it's happening
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Barrett's Esophagus Diagnosis | Endoscopy
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Barrett's Esophagus Treatment | Minor cell chgs
Photodynamic therapy (PDT)
Prohylactic esophagectomy
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Photodynamic therapy (PDT) | Take out piece of esophagus & replace w/jejunum or part of stomach
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Risk factors for Cancer of Esophagus | Barrett's
Alcohol
Tobacco
3x more common in men
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Cancer of Esophagus Mgmnt | Radiation
Chemotherapy
Surgery (Esophagectomy)
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Gastritis | Inflamation of the stomach
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Gastritis Patho | Lining can become swollen & ulcerate
Can cause perferation of lining = hemorrhage
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Acute Gastritis Clin. Manifest | Abdominal discomfort
Nausea
Vomiting
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Chronic Gastritis Clin. Manifest | Abdominal discomfort
Nausea
Vomiting
Heart burn
Pain
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Chronic Gastritis | Find the trigger
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The most common location for ulcers is | the duodenum.
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Peptic Ulcer Disease | Increased acid & decreased mucus allow acid to erode mucosal wall
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Peptic Ulcer Disease occurs in the | Stomach
Pylorus
Duodenum
Esophagus
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Increase gastric acid production | Caffeine
Smoking
Alcohol
Stress
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H. pylori | Bact will burrow into the lining allowing acid in to create an ulcer
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H. pylori requires | 2 different Ab's to cure
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Intractable Ulcers | Incurable Ulcers - (perform Vagotomy)
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Vagotomy | Cut Vagus nerve to decrease production of stomach acid - (incurable ulcers)
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Antrectomy - Billroth I | Take out lower portion of stomach to decrease stomach acid
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"Coffee Grounds" in stomach/vomit | Hemorrhage
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Peritinitis | Stomach leak out causing bacterial infection - sepsis
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Perforation complications can lead to | Peritinitis
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Any leakage into the abdominal cavity... | Requires Ab's
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Weight indications for surgery | BMI >40 or over 100 lbs overweight
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3 Categories of Bariatric Procedures | Malabsorptive
Restrictive
Combined Malabsorptive & Restrictive
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Rstrictive Surgery: | Reduces food intake
Decrease in appetite
Early satiety
Control of stoma
Craving control (Ghrelin)
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Laparoscopic Gastric Banding | Inflatable silicone band completely around upper portion of stomach
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Vertical Sleeve Gastrectomy (VSG) | 85% of stomach removed - shaped like small banana
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Gastric Bypass | Limits size of stomach and bypasses some of the small intestine
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Secretory Diarrhea | Bowel doesn't reabsorb water - it excretes water
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Osmotic Diarrhea | Pulling of water into the bowel
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Infectious Diarrhea | C-diff
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Antidiarrheals | Loperamide (Imodium)
Diphenoxylate (Lomotil)
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Loperamide | Imodium
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Diphenoxylate | Lomotil
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Constipation | Abnormal infrequency or irregularity of defications
Abnormal hardening of stools
Retention of stool in rectum
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Chronic Constipation | <3 bowel movements/week for 12 weeks in a 12 month period
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Bulk forming Laxatives | Psyllium (Metamucil)
Methylcellulose (Citrucel)
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Psyllium | Metamucil
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Methylcellulose | Citrucel
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Bulk forming Laxative Action | Promotes large soft stools by absorbing water into the intestines
Stimulates peristalsis
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Lubricant Laxatives | Mineral oil
Glycerin suppository
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Lubricant Laxative Action | Softens fecal matter and lubricates intestinal tract
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Stimulant Laxatives | Bisacodyl (Dulcolax)
Senna (Senokot)
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Bisacodyl | Dulcolax
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Senna | Senokot
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Stimulant Laxative Action | Irritates colonic epithelium by stimulating sensory nerve ending and increasing peristalsis
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Fecal softener Laxatives | Docusate (Colace)
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Docusate | Colace
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Fecal softener Laxative Action | Promotes incorporation of water into the stool resulting in softer fecal mass
More of daily treatment
1-5 days to take effect
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Osmotic Agent Laxatives | Polyethylene glycol and electrolytes
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Osmotic Agent Laxative Action | Rapidly pulls H2O into colon -> diarrhea out
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Common Hernia Locations | Inguinal
Femoral
Incisional
Umbilical
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Volvulus - Mech. Obstruction | Twisting of the bowel - caused by congenital abnormality
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Intussusception - Mech. Obstruction | Tunneling of bowel (folds in on itself)
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Paralytic illeus - Functional obstruction | No blockage, lack of movement (caused by surgery)
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Diverticulum | Sac like pouches -> sigmoid colon, usually
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Diverticulosis | Multiple Diverticulum
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Diverticulitis | Food or infection stuck in diverticula & cause inflammation
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Diverticular Disease | Submucosal layers of the colon herniate through the muscular wall
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Diverticular Disease Complications | Peritonitis
Abscess formation
Fistulas
Bleeding
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End-to-end anastomosis | Cut out bad bowel & reconnect
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Appendicitis | Food or infection gets lodged in the appendix
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Diarrhea is common in | Chrohn's Disease
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In Chrohn's Disease, constipation is | Occasional
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Blood in stool in Chrohn's Disease is | Occult Common
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Abdominal pain in Chrohn's Disease is | Typically mid-abdomen and right lower quadrant pain
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Fever in Chrohn's Disease is | Common
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Weight loss/growth failure in Chrohn's Disease is | Common
May occur for many months to years before diagnosis
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Perianal disease in Chrohn's Disease is | Common for:
Fistula/fissures
Abscesses/skin tags
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Diarrhea in Ulcerative Colitis is | Common, often with urgency
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Constipation in Ulcerative Colitis is | Rare without obstruction
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Blood in stool in Ulcerative Colitis is | Very common
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Abdominal pain in Ulcerative Colitis is | Cramping pain, often with stools
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Fever in Ulcerative Colitis is | Rare
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Weight loss/growth failure in Ulcerative Colitis is | Rare
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It is rare to have Perianal disease with | Ulcerative Colitis
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Chrohn's disease... | often recurs after surgery
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Ulcerative colitis... | is curable with a colectomy
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Right hemisphere | right now, present
pictures, sound, sight, smell
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Left hemisphere | past, future
associate present with past to prepare future
Broca's area - speech center
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Broca's area | Speech center, left hemisphere
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Magnetic Resonance Imaging | MRI
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Second largest part of brain Balance and coordination, assists in controlling body movements | Cerebellum
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Largest most advanced part of brain higher intellect, speech, movement, emotion, and integration or sensory stimuli | Cerbrum
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Handles automatic functions Respiration, heart rate, BP, arousal, wakefulness & attention | Brain Stem
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Artistic, creative, intuitive | Right hemisphere
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Logic, reasoning, linear | Left hemisphere
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Cerebral edema | any swelling of the brain
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Frontal lobes | Voluntary muscle movements
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Parietal lobes | regulate taste and touch
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Temporal lobes | regulate hearing & smell
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Occipital lobes | regulate vision
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3 ways Neurological Changes may affect the body | Structural
Metabolic
Drug Related
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Cardiovascular Respiratory Infection | 3 ways Neurological Changes may affect the body
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AEIOU Tips = A | acidosis, alcohol
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AEIOU Tips = E | epilepsy
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AEIOU Tips = I | infection
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AEIOU Tips = O | overdose
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AEIOU Tips = U | uremia
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AEIOU Tips = T | trauma
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AEIOU Tips = i | insulin
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AEIOU Tips = p | psychogenic
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AEIOU Tips = s | stroke
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Often, the first sign that a neurological event is already in progress | Restlessness
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Progressive dilation of pupils | increasing ICP
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Fixed pupils | very serious injury at midbrain or lower
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Corneal reflex is | unilateral or absent in coma
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Cheyne-stokes respirations mean that | lesion or injury is deep within cerebral hemispheres (death is usually imminent)
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CT Scan, MRI | Show displacement of brain structures
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EEG | studies brain's electrical activity
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Cerebral angiography | detects aneurysms, occluded vessels & tumors w/in cerebral arts/veins
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Transcranial Doppler | assesses cerebral blood flow
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Lumbar puncture | CSF detects blood, WBCs, meningitis
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The 2 essential things the brain needs to survive are | O2 & glucose
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Brain | 80% of skull's contents
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CSF | 10% of skull's contents
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Blood | 10% of skull's contents
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Hypercapnia | Increased cerebral vasodilation then increased blood flow then increased ICP
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Hypoxemia | Cerebral vasodilation, which raises ICP
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Vasodilator drugs | increase cerebral blood flow -> temp increased ICP (Nitroglycerin)
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Cerebral Perfusion Pressure | Pressure needed to perfuse brain cells
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Normal CPP | 70-100 mm Hg
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CPP < 50 | irreversible brain dmg
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