Est/progest drug drill
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| what are routes of admin? | po, transd, vag, parenteral
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| name 2 SERMs | *tamoxifen
*raloxifene
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| why is tamoxifen given? | tx breast ca, osteoporosis, +lipid effects (other drugs better)
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| what are ADRs for tamoxifen | *hot flashes
*VTE
*endometrial ca
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| why is raloxifine given? | *breast ca
*osteoporosis
*+ lipid effets (other drugs better)
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| what are ADRs for raloxifine | *Hot flashes
*VTE
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| What is one benefit of raloxifine | it does not produce endometrial proliferation
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| Name 2 drugs given for HRT | premarin, pempro
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| What HRT given for in tact uterus | pempro given for this uterine status
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| what is HRT class of pempro | EPT is this drug's class
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| What HRT given for s/p hysterectomy | premarin given for this uterine status
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| What is HRT class of premarin | ET is this drug's class
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| Ulipristal (ellaOne) is what type of drug | coming soon ECP, acts as an ovulation antagonist
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| Yuzpe Method is a COC containing | ethinyl estradiol & levonorgesterol in this ECP
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| What are the brand names of 3 POC ECP's | Plan B, Next Choice, Plan B One Choice
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| Ingredient/dosage of Plan B/Next Choice | levonorgestrel 0.75 mg po q 12 x 2 doses
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| Ingredient/dosage Plan B One Step | levonorgestrel 1.5mg po 1 DOSE ASAP
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| Yuzpe method is what? | ECP - COC
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| what is the main s/e difference betw Yuzpe & Plan B/Next Choice/Plan B One Step | there is far less n/v with POCs due to lack of estrogen
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| type of estrogen used in COCs | Ethinyl estradiol used in this class
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| type of estrogen used in COCs | estradiol valerate used in this class
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| type of estrogen used in COCs | mestranol (which metabolizes to ethinyl estradiol)
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| First generation progestins in POC | northindrone, northindrone acetate
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| First generation progestins in POC | *norgesterol, levo-norgesterol
*ethynodiol diacetate
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| Second generation progestins in POC | *desogestrel
*norgestimate
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| Third generation progestins in POC | drospirenone
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| 4th phase Natazia POC | dienogest
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| What characteristic decreases with each generation of POC? | there is a decreasing adrogenic and anabolic activity
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| OrthoEvra route & MOA | transdermal & COC MOA
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| What is in OrthoEvra transdermal? | ethinyl estradiol and norelgestromin (a norgestimate metabolite)
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| OrthoEvra fun facts | wear for 3 weeks, one week off for withdrawal bleeding. Dec. effectiveness > 90 kg
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| Nuvaring COC ingredients | ethinyl estradiol, etonogestrel (desogestrel metabolite)
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| Implants Norgestrel, Norplant 2, Implanon MOA | these are progestin only, effective for 3 years
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| what's in subdermal implants | etonogestrel (metabolite of desogestrel) is in this long-term effective product
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| What is DMPA | depot medroxyprogesterone acetate
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| DMPA's MOA / dosage | IM: 150 mg q 3 months
Newer version is SQ 104 mg q 3 months
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| What is drawback to DMPA | irregular menstruation, bleeding, BTB. But will be amenorrhagic within 6-12 mo.
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| Three types of IUD and duration of action | *copper paragaurd - 10 yrs
*Mirena - levonorgesterol - 5 years
*porgestogen - 1 year - no longer on market
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| Spermicide active ingredient | *octoxynol
*nonoxynol 9
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| Today sponge in this class | spermicide
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| fun fact about spermicides | use within 1 h of intercourse, repeat if you are so fortunate as to have subsequent episodes
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| barrier examples and fun facts | male, female condoms, diaphragms, cervical caps. Latters must be fitted by HCP
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Created by:
lorrelaws
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