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NURS 572 60-61
Est/progest drug drill
| Question | Answer |
|---|---|
| what are routes of admin? | po, transd, vag, parenteral |
| name 2 SERMs | *tamoxifen *raloxifene |
| why is tamoxifen given? | tx breast ca, osteoporosis, +lipid effects (other drugs better) |
| what are ADRs for tamoxifen | *hot flashes *VTE *endometrial ca |
| why is raloxifine given? | *breast ca *osteoporosis *+ lipid effets (other drugs better) |
| what are ADRs for raloxifine | *Hot flashes *VTE |
| What is one benefit of raloxifine | it does not produce endometrial proliferation |
| Name 2 drugs given for HRT | premarin, pempro |
| What HRT given for in tact uterus | pempro given for this uterine status |
| what is HRT class of pempro | EPT is this drug's class |
| What HRT given for s/p hysterectomy | premarin given for this uterine status |
| What is HRT class of premarin | ET is this drug's class |
| Ulipristal (ellaOne) is what type of drug | coming soon ECP, acts as an ovulation antagonist |
| Yuzpe Method is a COC containing | ethinyl estradiol & levonorgesterol in this ECP |
| What are the brand names of 3 POC ECP's | Plan B, Next Choice, Plan B One Choice |
| Ingredient/dosage of Plan B/Next Choice | levonorgestrel 0.75 mg po q 12 x 2 doses |
| Ingredient/dosage Plan B One Step | levonorgestrel 1.5mg po 1 DOSE ASAP |
| Yuzpe method is what? | ECP - COC |
| what is the main s/e difference betw Yuzpe & Plan B/Next Choice/Plan B One Step | there is far less n/v with POCs due to lack of estrogen |
| type of estrogen used in COCs | Ethinyl estradiol used in this class |
| type of estrogen used in COCs | estradiol valerate used in this class |
| type of estrogen used in COCs | mestranol (which metabolizes to ethinyl estradiol) |
| First generation progestins in POC | northindrone, northindrone acetate |
| First generation progestins in POC | *norgesterol, levo-norgesterol *ethynodiol diacetate |
| Second generation progestins in POC | *desogestrel *norgestimate |
| Third generation progestins in POC | drospirenone |
| 4th phase Natazia POC | dienogest |
| What characteristic decreases with each generation of POC? | there is a decreasing adrogenic and anabolic activity |
| OrthoEvra route & MOA | transdermal & COC MOA |
| What is in OrthoEvra transdermal? | ethinyl estradiol and norelgestromin (a norgestimate metabolite) |
| OrthoEvra fun facts | wear for 3 weeks, one week off for withdrawal bleeding. Dec. effectiveness > 90 kg |
| Nuvaring COC ingredients | ethinyl estradiol, etonogestrel (desogestrel metabolite) |
| Implants Norgestrel, Norplant 2, Implanon MOA | these are progestin only, effective for 3 years |
| what's in subdermal implants | etonogestrel (metabolite of desogestrel) is in this long-term effective product |
| What is DMPA | depot medroxyprogesterone acetate |
| DMPA's MOA / dosage | IM: 150 mg q 3 months Newer version is SQ 104 mg q 3 months |
| What is drawback to DMPA | irregular menstruation, bleeding, BTB. But will be amenorrhagic within 6-12 mo. |
| Three types of IUD and duration of action | *copper paragaurd - 10 yrs *Mirena - levonorgesterol - 5 years *porgestogen - 1 year - no longer on market |
| Spermicide active ingredient | *octoxynol *nonoxynol 9 |
| Today sponge in this class | spermicide |
| fun fact about spermicides | use within 1 h of intercourse, repeat if you are so fortunate as to have subsequent episodes |
| barrier examples and fun facts | male, female condoms, diaphragms, cervical caps. Latters must be fitted by HCP |
Created by:
lorrelaws
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