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Quiz Magnesium Questions Chapter 17 Lewis p. 319

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Question
Answer
Magnesium is the 2nd most abundant cation in ICF or ECF?   ICF  
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Approximately 50% to 60% of body’s magnesium is contained in?   Bone  
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Magnesium functions as a coenzyme in the metabolism of?   CHO and protein  
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Magnesium is also involved in metabolism of?   Nucleic acid and proteins  
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Magnesium is regulated by?   GI absorption and renal excretion  
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Which organs are able to conserve magnesium in times of need and excrete excesses?   Kidneys  
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True or False Factors that regulate calcium balance appear similarly to influence magnesium balance:   True such as PTH  
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Why would manifestations of magnesium imbalance be mistaken for calcium imbalance?   Because magnesium imbalance is related to calcium and potassium balance, all three cations should be assessed together.  
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Name some of the causes of magnesium imbalance Hypomagnesemia (Table 17-10 p 320):   1. Diarrhea 2. Vomiting 3. Chronic alcoholism 4. Impaired GI absorption 5. Malabsorption syndrome 6. Prolonged malnutrition 7. Large urine output 8. NG suction 9. Poorly controlled diabetes mellitus 10. Hyperaldosteronism  
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Name some of the causes of magnesium imbalance Hypermagnesemia (Table 17-10 p 320):   1.Renal failure (especially if patient is given magnesium products) 2. Excessive administration of magnesium for treatment of eclampsi 3. Adrenal insufficiency  
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Why is neuromuscular excitability profoundly affected by alterations in serum magnesium level?   Because magnesium acts directly on the myoneural junction  
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How does hyermagnesemia usually occur?   Increase in magnesium intake accompanied by renal insufficiency or failure  
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A patient with what kind of disease should not ingest products containing magnesium such as Maalox and MOM?   A patient with chronic kidney disease  
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Initial clinical manifestations of a mildly elevated serum magnesium concentration include the following:   1. Lethargy 2. Drowsiness 3. Nausea 4. Vomiting  
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As the level of magnesium increase, describe the clinical manifestations as they become more profound:   1. Deep tendon reflexes are loss 2. Somnolence 3. Respiratory and cardiac arrest  
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Management of hypermagnesemia should focus on:   Prevention  
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Persons with kidney disease should NOT take:   Magnesium containing drugs and must be cautioned to review all over the counter drug labels for magnesium content  
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What is the emergency treatment of hypermagnesemia?   IV administration of calcium chloride or calcium gluconate to physiologically oppose the effects of the magnesium on cardiac muscle.  
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How will promoting urinary excretion with fluid affect magnesium?   It will decrease serum magnesium levels  
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The patient with impaired renal function will require dialysis. Why?   because the kidneys are the major route of excretion for magnesium  
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What is the major cause of hypomagnesemia?   Prolong fasting or starvation  
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What chronic activity commonly causes hypomagnesemia?   Chronic alcoholism as result of insufficient food intake.  
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How does fluid loss from GI tract contribute to hypomagnesemia?   Interferes with Mg2+ absorption  
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How can prolong parenteral nutrition contribute to hypomagnesemia?   Prolong parenteral nutrition without magnesium supplement hypomagnesemia  
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How do many diuretics affect the level of magnesium?   Many diuretics increase the risk of magnesium loss through renal excretion  
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How does osmotic diuresis affect magnesium levels?   Osmotic dieresis caused by high glucose levels in uncontrolled diabetes mellitus increases renal excretion of magnesium  
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What are the clinical significant manifestations of hypomagnesemia?   1. Confusion 2. Hyperactive deep tendon reflexes 3. Tremors 4. Seizures 5. Predispose to cardiac dysrhythmias  
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Clinically, hypomagnesemia resembles what other deficiency?   Hyopcalcemia and hypomagnesemia may contribute to hypocalcemia as a result of decreased action of PTH.  
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Explain how hypomagnesemia associated with hypokalemia does not respond well to potassium replacement?   This occurs because intracellular magnesium is critical to normal function of the sodium potassium pump  
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Mild magnesium deficiencies can be treated with:   Oral supplements and increased dietary intake of foods high in magnesium  
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List some food rich in magnesium:   1. Green vegetables 2. Nuts 3. Bananas 4. Oranges 5. Peanut butter 6. Chocolate  
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Severe magnesium deficiencies can be treated with:   Parenteral IV or IM magnesium (Magnesium sulfate). Too rapid administration of magnesium can lead to cardiac or respiratory arrest  
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