Med Surg III
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each of the black spaces below before clicking
on it to display the answer.
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DMARDS | methotrexate Rheumatrex, Trexall
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DMARDS | penicillamine Cuprimine, Depen
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DMARDS | sulfasalazine Azulfidine, Salazopyrin
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DMARDS | leflunomide Arava
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Antimalarial | hydroxychloroquine Plaquenil
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Biologic Targeted Therapy | etanercept Enbrel
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Biologic Targeted Therapy | infliximab Remicade
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Biologic Targeted Therapy | adalimumab Humira
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Biologic Targeted Therapy | anakinra Kineret
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Biologic Targeted Therapy | abatacept Orencia
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Biologic Targeted Therapy | rituximab Rituxan
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methotrexate | rapid anti-inflammatory effect
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penicillamine Cuprimine, Depen | Inhibits T cell function, impairs antigen presentation.
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Sulfasalazine, Azulfidine Salazopyrin | Blocks prostaglandin formation
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leflunomide Arava | Inhibits proliferation of lymphocytes, blocks immune cell overproduction
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Hydroxychloroquine Plaquenil | suppress formation of antigens, inhibits lysosomal enzymes
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Etanercept Embrel | Engineered copy of the TNF cell receptor, Binds TNF before TNF can by to the cell surface receptor
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Infliximab Remicade | monoclonal antibody that binds to TNF
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adalimumab Humira | monoclonal antibody that binds to TNF reduces infilitration of inflammotory cells
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anakinra Kineret | blocks the action of interleukin decreased inflammatory response
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Abatacept Orencia | Modulates T cells activation, suppresses immune response
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Rituximab Rituxan | monoclonal antibody that targets b cells
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Gold compounds | alters immune response, inhibits T and B cell activity, suppressing synoviitis of active ra.
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Corticosteriods | inhibits synthesis/release of mediators of inflammtion
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methotrexate rheumatrex trexall | hepatoxicity, bone marrow suppression, nephrotoxicity sustained cough
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penicillamine Cupramine Depen | GI irritation, reduces alters taste, proteinuria, hamaturia, rash fe def anemia
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Sulfasalazine Azulfidine Salazopyrin | Gi effects, bleeding, bruising, jaundice, rash, HA, uticaria, purititis. Discoloration urine et skin.
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