Immunologically Relevant Molecules
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
|
|
||||
|---|---|---|---|---|---|
| Mechanism for isotype switching? | show 🗑
|
||||
| Ig produced in primary (immediate) response to an antigen | show 🗑
|
||||
| show | IgA
🗑
|
||||
| show | IgG (*G*ift from mother)
🗑
|
||||
| show | IgD
🗑
|
||||
| show | IgE
🗑
|
||||
| show | IgE
🗑
|
||||
| show | IgG
🗑
|
||||
| Found in breast milk | show 🗑
|
||||
| show | IgA
🗑
|
||||
| show | IgM
🗑
|
||||
| Only Ig when class switching cannot occur | show 🗑
|
||||
| show | IgM
🗑
|
||||
| show | C1
🗑
|
||||
| show | C5-C9
🗑
|
||||
| show | increased susceptibility to type 3 hypersensitivity reactions
🗑
|
||||
| Cell surface proteins: T cells (general) | show 🗑
|
||||
| show | CD4, CD40L
🗑
|
||||
| show | CD8
🗑
|
||||
| Cell surface proteins: B cells | show 🗑
|
||||
| show | MHC II, CD 14, CD16, CD40, Fc and C3b receptors
🗑
|
||||
| show | MHC I, CD16 (binds Fc of IgG), CD56 (unique marker for NK)
🗑
|
||||
| show | MHC I
🗑
|
||||
| Cell surface proteins: WBC, RBC, and platelets (protect against complement-mediated damage) | show 🗑
|
||||
| show | Tetanus toxin, Botulinum toxin, HBV, or Rabies virus (To Be Healed Rapidly)
🗑
|
||||
| show | RSV
🗑
|
||||
| Type I MHC is on what cells | show 🗑
|
||||
| Type II MHC is on what cells | show 🗑
|
||||
| Name the antigen presenting cells | show 🗑
|
||||
| show | Type I
🗑
|
||||
| show | Type II (Antigen presenting cells)
🗑
|
||||
| show | Nonspecific, Rapid, Physical barriers, Phagocytosis, Complement, Interferons, Induces inflammation
🗑
|
||||
| show | Specific; Slow, then rapid; Inducible; Memory; Antibodies; B and T cells
🗑
|
||||
| Alpha & Beta interferons are produced by? | show 🗑
|
||||
| show | Place uninfected cells in "antiviral state": Alpha & beta induce a 2nd protein which degrades viral (but not host) mRNA thereby inhibiting viral protein synthesis
🗑
|
||||
| show | 1) alpha & beta interferons inhibit viral protein synth, 2) gamma-interferons incr. MHC I and II expression & antigen presentation in all cells, 3) Activate NK cells to kill virus-infected cells
🗑
|
||||
| show | Formed in bone marrow, Multilobar nuclei, granules, Early defense against bacteria
🗑
|
||||
| Cells increased in pyogenic infections | show 🗑
|
||||
| Macrophages develop in ___ as ___ | show 🗑
|
||||
| show | Release of pharmacologically active substances contained within granules - Allergies
🗑
|
||||
| show | Major role against parasites - Secretion of eosinophilic granules results in damage to parasite membrane. Also involved in asthma & allergy
🗑
|
||||
| NK cells target? | show 🗑
|
||||
| show | Inhibitory - recognizes MHC alpha chains; Stimulatory - recognizes cell signals
🗑
|
||||
| show | Classical: Aquired, Alternative: Innate, Lectin: Innate
🗑
|
||||
| show | System of proteins that interact to play a role in humoral immunity & inflammation
🗑
|
||||
| show | 1. Lysis of cells, bacteria, viruses, 2. Opsonization to promote phagocytosis of Ag, 3. Activation of inflammatory response , 4. Clearance of immune complexes
🗑
|
||||
| Describe the classical pathway complement cascade. | show 🗑
|
||||
| Factors B, D and properdin are part of which complement pathway only? | show 🗑
|
||||
| MAC lyses what? | show 🗑
|
||||
| show | gram(+) bacteria have thick PG coats and MAC has trouble creating pores in it
🗑
|
||||
| show | IgG or IgM ("GM makes classic cars")
🗑
|
||||
| show | molecules on the surface of microbes, especially LPS
🗑
|
||||
| 2 primary opsonins in bacterial defense | show 🗑
|
||||
| show | C1, C2, C3, C4
🗑
|
||||
| show | C3b
🗑
|
||||
| show | C3a, C5a (allergic response, degranulation of eosinophils)
🗑
|
||||
| Complement factor involved in neutrophil chemotaxiS | show 🗑
|
||||
| show | C5b, C6, C7, C8, C9
🗑
|
||||
| Associated with C1 and C4 deficiencies | show 🗑
|
||||
| Associated with C3 deficiencies | show 🗑
|
||||
| show | chronic neutropenia
🗑
|
||||
| show | hereditary angioedema (overactive complement)
🗑
|
||||
| Deficiency of C6-C8 | show 🗑
|
||||
| Deficiency of decay accelerating factor (DAF) | show 🗑
|
||||
| show | SLE & other autoimmune diseases
🗑
|
||||
| anti-dsDNA, anti-Smith | show 🗑
|
||||
| show | Rheumatoid arthritis (anti-IgG = "Rheumatoid Factor")
🗑
|
||||
| HLA-B27 | show 🗑
|
||||
| HLA-DR2 | show 🗑
|
||||
| show | IL-1
🗑
|
||||
| show | IL-2
🗑
|
||||
| show | IL-3 (secreted by activated T cells)
🗑
|
||||
| show | IL-4
🗑
|
||||
| Cytokine that enhances class switching of IgA | show 🗑
|
||||
| show | IL-5
🗑
|
||||
| show | IL-6
🗑
|
||||
| show | IL-8 (also, C5a)
🗑
|
||||
| show | IL-10 (secreted by Th2 cells themselves)
🗑
|
||||
| Cytokine that activates NK cells and Th1 cells | show 🗑
|
||||
| show | TGF-beta
🗑
|
||||
| Cytokine increasing IL-2 receptor synthesis by Th cells, and increases B cell proliferation | show 🗑
|
||||
| Cytokine NOT produced in Job's syndrome--> "cold" staph abscesses | show 🗑
|
||||
| Signals required for activation of helper T cells | show 🗑
|
||||
| Signals required for activation of cytotoxic T cells | show 🗑
|
||||
| Cell surface proteins of Helper T cells | show 🗑
|
||||
| show | CD8, TCR, CD3
🗑
|
||||
| Cell surface proteins of B cells | show 🗑
|
||||
| show | MHC II, CD14, Receptors for Fc & C3b
🗑
|
||||
| show | Receptors for MHC I, CD16, CD56
🗑
|
||||
| show | MHC I
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
srebeiro
Popular USMLE sets