Day 15.3
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| show | Spectrin (biconcavity and flexibility)
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| show | Polycythemia vera, renal cell CA, pheochromocytoma, hemangioblastoma, chronic hypoxia (COPD, Obstructive Sleep Apnea/OSA), Down syndrome (at birth)
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| show | Factor 8 (Ate)
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| show | Factor 9 (B9)
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| show | Protein C and S, and factors 2, 7, 9, and 10
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| show | Protamine sulfate
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| show | Vit K and fresh frozen plasma
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| show | PTT
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| What lab value is used to monitor the following medications: warfarin? | show 🗑
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| What lab value is used to monitor the following medications: enoxaparin? | show 🗑
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| What is the treatment for heparin induced thrombocytopenia (HIT)? | show 🗑
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| What are the 3 steps of platelet stimulation? | show 🗑
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| show | Von Willebrand's Factor
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| What pathologic form of RBC would you see in the following diseases?: lead poisoning | show 🗑
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| What pathologic form of RBC would you see in the following diseases?: G6PD deficiency | show 🗑
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| show | schistocytes/helmet cells
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| What pathologic form of RBC would you see in the following diseases?: abetalipoproteinemia | show 🗑
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| What pathologic form of RBC would you see in the following diseases?: asplenia | show 🗑
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| Iron-protein complex that acts as a cellular storage protein for iron and is an acute phase reactant | show 🗑
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| Protein that binds ferric molecules and transports them through the plasma. | show 🗑
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| show | It is synthesized in the liver. Levels increase with iron deficiency.
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| show | Potent vasoconstriction (keeps clot from washing away), platelet aggregation (par excellence!), and bronchoconstriction (can cause problems in asthmatics)
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| show | Thrombin; pro-coagulation; coagulase can also convert fibrinogen to fibrin
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| What amino acid change is responsible for sickle cell disease? | show 🗑
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| show | Glu-->Lys in beta chain
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| show | Adult has 2 alpha and 2 beta chains. Fetal replaces the 2 beta chains with 2 gamma chains (2 alpha, 2 gamma)
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| show | Normal Hbg gets non-enzymatically glycosylated (glucose gets attached to it), creating Hb A1c (Goljan said this was important to know!)
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| What diseases occur when there are no alpha chains in hemoglobin? | show 🗑
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| show | Plummer Vinson syndrome (Fe deficiency anemia)
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| show | Beta thalassemia minor
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| What is the cause of anemia given the following statement?: megaloblastic anemia not correctable by B12 or folate | show 🗑
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| show | B12 deficiency
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| What is the cause of anemia given the following statement?: microcytic anemia + basophilic stippling | show 🗑
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| What is the cause of anemia given the following statement?: microcytic anemia reversible with B6 | show 🗑
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| show | zidovudine
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| show | paroxysmal noctural hemoglobinuria (PNH)
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| show | chronic kidney disease (low erythropoietin levels)
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| show | Direct Coomb's Test (DAT)
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| show | 1. Hemolytic disease of the newborn
2. Drug induced autoimmune hemolytic anemia
3. Hemolytic transfusion rxns
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| What test am I? Pt's serum is incubated with normal RBCs to detect for the presence of Abs. | show 🗑
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| Name 2 situations in which an indirect Coomb's test might be used. | show 🗑
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| show | Cold agglutinins
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| show | IgM
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| show | 1. Mycoplasma pneumoniae
2. EBV
3. Some malignancies
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| show | Warm agglutinins
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| show | IgG
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| Name 4 conditions you would see warm agglutinins in. | show 🗑
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| show | Delta-aminolevulonic acid synthase
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| What is the cause of ITP (idiopathic thrombocytopenic purpura)? | show 🗑
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| What is the defect in Bernard Soulier disease? | show 🗑
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| show | von Willebrand's disease
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| What are some of the hereditary syndromes of thrombosis (4)? | show 🗑
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| show | PNH diagnosis
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| show | Fanconi's anemia diagnosis
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| What disease am I used to test for?: Heinz bodies | show 🗑
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| What disease am I used to test for?: D dimers | show 🗑
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| show | Thalassemia, anemia of chronic disease, Fe deficiency anemia, and lead poisoning (key one to know)
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| What disease am I used to test for?: osmotic fragility test | show 🗑
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| What disease am I used to test for?: + risocetin test | show 🗑
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| What rapid onset, rapidly progressive disease presents with over 50% myeloblasts in the bone marrow, numerous immature blast cells, and is associated with pancytopenia (anemia, bleeding tendency, and infection)? | show 🗑
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| What rapid onset, rapidly progressive disease presents with over 50% lymphoblasts in the bone marrow, numerous immature blast cells, and is associated with pancytopenia (anemia, bleeding tendency, and infection)? | show 🗑
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| show | ALL
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| show | AML
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| Which acute leukemia commonly has bone pain? | show 🗑
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| Which acute leukemia is associated with the Tdt enzyme? | show 🗑
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| Which acute leukemia is PAS+? | show 🗑
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| What is the prognosis of ALL? | show 🗑
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| show | AML
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| Which acute leukemia has Auer rods? | show 🗑
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| Which acute leukemia is PAS -? | show 🗑
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| Name 3 medical interventions a/w AML. | show 🗑
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| show | 1. Down syndrome
2. Fanconi syndrome
3. Bloom syndrome
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| Myeloproliferative disease, myelodysplastic syndrome, and aplastic anemia have what cancer risk factor in common? | show 🗑
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| Which cancer can be treated with all-trans retinoic acid? What is the assoc'd translocation? | show 🗑
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| What cancer am I?: t(9;22) | show 🗑
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| show | Burkitt lymphoma (c-myc)
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| What cancer am I?: t(11;22) | show 🗑
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| show | Manle cell lymphoma
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| What cancer am I?: t(14;18) | show 🗑
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| Proliferative disorder of dendritic cells. Birbeck granules on EM are characteristic; S100 and CD1a +. | show 🗑
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Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
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To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
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Created by:
sarah3148
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