LCC NURS 200 unit 5 Cholesterol Drugs
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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Antiplatelet Drugs Prototype | Asprin
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Antiplatelet Drugs MOA | Block receptor sites on platelet membrane.
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Antiplatelet Drug Indications | Patients at risk for thromboembolic events (stroke, MI)
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Antiplatelet Drug Adverse Effects | Bleeding, GI distress, headache, dizziness, weakness.
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Anticoagulant Prototype | Heparin, enoxaparin (Lovenox), dalteparin (Fragmin), warfarin (Coumadin)
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Anticoagulants Indications | Prevents clots from forming/existing clots from growing in patients with thrombo-embolic event risk factors.
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Anticoagulants Adverse Effects | Bleeding, Thrombocytopenia, nausea, vomiting, abdominal cramps.
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Anticoagulants Contraindications/Cautions | Any condition that oculd be worsened by increased bleeding tendency.
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Anticoagulants Interaction | Warfarin has MANY, Nitroglycerine decreases effect of Heparin.
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Heparin Nursing Implications | Monitor effects of heparin by activated partial thromboplastin times (APTT or PTT), parenteral only, short half-life,
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Heparin antidote prototype | protamine sulfate
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Low-molecular weight heparins nursing implications | Somewhat safer and more predictable response, don’t require frequent lab monitoring, given subQ – not oral or IV.
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Warfarin (Coumadin) Nursing Implications | given orally only, several days to achieve therapeutic levels, monitored by prothrombine time (PT) and INR.
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Warfarin (Coumadin) antidote prototype | Vitamin K
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Thrombolytic Agent Prototype | streptokinase (Streptase, Kabikinase)
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Thrombolytic Agent MOA | convert plasminogen to plasmin wich breaks down fibrin threads in clots.
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Thrombolytic Indcations | Acute MI, Stroke and pulmonary embolus
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Thrombolytic Adverse Effects | Bleeding, Allergy/anaphylaxis
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Thrombolytic Contraindications/Cautions | Any condition where clotting is desirable (recent surgery, trauma, active bleeding).
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Thrombolytic Interactions | Other anticoagulants/antiplatelet meds must be closely monitored.
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