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Unit 5 Cholesterol

LCC NURS 200 unit 5 Cholesterol Drugs

Antiplatelet Drugs Prototype Asprin
Antiplatelet Drugs MOA Block receptor sites on platelet membrane.
Antiplatelet Drug Indications Patients at risk for thromboembolic events (stroke, MI)
Antiplatelet Drug Adverse Effects Bleeding, GI distress, headache, dizziness, weakness.
Anticoagulant Prototype Heparin, enoxaparin (Lovenox), dalteparin (Fragmin), warfarin (Coumadin)
Anticoagulants Indications Prevents clots from forming/existing clots from growing in patients with thrombo-embolic event risk factors.
Anticoagulants Adverse Effects Bleeding, Thrombocytopenia, nausea, vomiting, abdominal cramps.
Anticoagulants Contraindications/Cautions Any condition that oculd be worsened by increased bleeding tendency.
Anticoagulants Interaction Warfarin has MANY, Nitroglycerine decreases effect of Heparin.
Heparin Nursing Implications Monitor effects of heparin by activated partial thromboplastin times (APTT or PTT), parenteral only, short half-life,
Heparin antidote prototype protamine sulfate
Low-molecular weight heparins nursing implications Somewhat safer and more predictable response, don’t require frequent lab monitoring, given subQ – not oral or IV.
Warfarin (Coumadin) Nursing Implications given orally only, several days to achieve therapeutic levels, monitored by prothrombine time (PT) and INR.
Warfarin (Coumadin) antidote prototype Vitamin K
Thrombolytic Agent Prototype streptokinase (Streptase, Kabikinase)
Thrombolytic Agent MOA convert plasminogen to plasmin wich breaks down fibrin threads in clots.
Thrombolytic Indcations Acute MI, Stroke and pulmonary embolus
Thrombolytic Adverse Effects Bleeding, Allergy/anaphylaxis
Thrombolytic Contraindications/Cautions Any condition where clotting is desirable (recent surgery, trauma, active bleeding).
Thrombolytic Interactions Other anticoagulants/antiplatelet meds must be closely monitored.
Created by: npeters519