HY - Bill's Rate Limiting Enzymes - One-Liners
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| RLE of Glycolysis | show 🗑
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| RLE of Gluconeogenesis | show 🗑
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| show | Isocitrate dehydrogenase
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| show | Glycogen Synthase
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| RLE of glycogenolysis | show 🗑
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| show | Glucose-6-phosphate dehydrogenase
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| show | CPS II
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| RLE of Purine sythesis | show 🗑
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| RLE of Urea cycle | show 🗑
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| RLE of Fatty acid sythesis | show 🗑
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| RLE of fatty acid oxidation | show 🗑
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| show | HMG-CoA synthase
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| RLE of Cholesterol sythesis | show 🗑
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| What processes are NADPH used in? | show 🗑
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| show | 1) Decreases because you have lots of energy 2) Increases because you have no energy 3) Decreases because the TCA cycle needs to catch up 4) Increases because you need to further drive glycolysis
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| What cofactors are required for pyruvate dehydrogenase and α-ketoglutarate dehydrogenase? | show 🗑
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| show | Increased levels of NAD+/NADH, ADP, and Ca+ **high levels of the above suggests you need energy**
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| show | Glucose, Lactate, Acetyl-CoA, Oxaloacetate, and Alanine
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| What is the purpose of the Cori Cycle? | show 🗑
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| show | To make NADPH for glutathione protection and ribose
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| What disease is caused by failure to make NADPH and protect against free radical damage? | show 🗑
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| show | Aldolase B
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| show | Fructokinase
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| show | Essential Frucosuria is benign (Fructose intolerance has hypoglycemia, jaundice, cirrhosis and vomiting)
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| What enzyme is deficient in Classic Galactosemia? | show 🗑
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| show | galactokinase
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| show | failure to thrive, jaundice, cataracts, hepatomegaly, MR
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| show | mild condition, galactose in urine, cataracts, no social smile
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| show | Ornithine transcarbamoylase deficiency (OTC)
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| show | High Orotic acid, decreased BUN, hyperammonemia
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| What can be made from Phenylalanine? | show 🗑
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| show | Serotonin, Melatonin, Niacin
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| What can be made from Histidine? | show 🗑
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| show | Porphyrin, Heme
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| show | Creatine, Urea, and Nitric Oxide
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| What can be made from Glutamate? | show 🗑
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| What is the cause of Phenylketonuria? | show 🗑
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| What is the cause of alkaptonuria (ochronosis)? | show 🗑
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| What is the cause of albinism? | show 🗑
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| What causes homocystinuria? | show 🗑
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| What are the symptoms of homocystinuria? | show 🗑
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| What is the cause of cystinuria? | show 🗑
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| show | Cystine Kidney stones (Rx. Acetazolamide to increase pH)
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| show | Can't degraded branched chain A.As (Ile, Leu, Val)
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| Which disease results in loss of tryptophan in the urine and leads to pellagra? | show 🗑
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