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LCC NURS 200 unit 4 prototypes

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Question
Answer
Levodopa (Dopar)   Parkinson's MOA: Converts to Dopamine in the brain  
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Levodopa/Carbidopa (Sinemet)   Parkinson's  
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MOA: Converts to Dopamine in the brain"   Benefits over Levodopa - decreased metabolism of drug allows lower dosing.  
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Phenytoin (Dilantin)   Epilepsy - partial and tonic-clonic seizures  
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Carbamazepine (Tegretol)   Epilepsy: partial and tonic-clonic seizures Bipolar disorder, neuropathic pain and off label for migranes due to peripheral nerve damage. AE: nystagmus, ataxia, sedation, bone marrow suppression, leukopenia, anemia, thrombocytopenia, skin rashes.Grapefr  
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Ethosuximide (Zarontin)   Absence seizures  
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Lamotigine (Lamictal)   Partial and generalized seizures, neuropathy pain, bipolar disorder, migranes.  
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Morphine   Opioid Agonist - Moderate to Severe pain (cough center suppression, diarrhea treatment, balanced anesthesia).  
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Naloxone (Narcan)   Opioid Antagonist Indication: opioid toxicity/overdose  
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Pentazocine (Talwin)   Opioid Agonist-Antagonist; Mild to moderate pain. MOA: Agonist at Kappa Antagonist at Mu  
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Sumatriptin (Imitrex)   Triptan (Serotonin Receptor Agonist)Indication: Abortion of migrane headahces and cluster headaches. MOA: Serotonin agonist; selective receptors in brain, causes vasoconstriction (necessary) and suppresses inflammatory mediators.  
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Haloperidol (Haldol)   1st generation antipsychotic  
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Clozapine (Clozaril)   2nd generation antipsychotic  
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Imipramine (Tofranil)   Tricyclic Antidepressant  
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Fluoxetine (Prozac)   SSRI MOA: reuptake or serotonin. Indication: depression, anxiety disorders.  
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Duloxetine (Cymbalta)   SNRI MOA: block reuptake of serotonin and norepinephrine. Indication: depression, anxiety disorders.  
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MAOI's   MOA: irreversibly inhibit MAO enzyme (breaks down seretonin, NE and dopamine). Indication: depression refractory to SSRI and SNRI drugs.  
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Lithium salts   Indication: bipolar disorder adjunct with anti epileptic drug.  
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Diazepam (Valium)   Benzodiazepines Indication: chronic and acute anxiety, sleep disorders, muscle spasm, seizure, sedation, alcohol withdrawl, anti-epileptic, balanced anesthesia.MOA: Increase GABA in CNS  
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Pehenobarbital   Barbituates  
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Methylphenidate (Ritalin, Concerta);Dextroamphetamine (Adderall, Adderall XXR)   CNS Stimulant for ADD/ADHD MOA: Promote release of NE and inhibit reuptake of NE and Dopamine.  
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