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Unit 4 Prototypes

LCC NURS 200 unit 4 prototypes

Levodopa (Dopar) Parkinson's MOA: Converts to Dopamine in the brain
Levodopa/Carbidopa (Sinemet) Parkinson's
MOA: Converts to Dopamine in the brain" Benefits over Levodopa - decreased metabolism of drug allows lower dosing.
Phenytoin (Dilantin) Epilepsy - partial and tonic-clonic seizures
Carbamazepine (Tegretol) Epilepsy: partial and tonic-clonic seizures Bipolar disorder, neuropathic pain and off label for migranes due to peripheral nerve damage. AE: nystagmus, ataxia, sedation, bone marrow suppression, leukopenia, anemia, thrombocytopenia, skin rashes.Grapefr
Ethosuximide (Zarontin) Absence seizures
Lamotigine (Lamictal) Partial and generalized seizures, neuropathy pain, bipolar disorder, migranes.
Morphine Opioid Agonist - Moderate to Severe pain (cough center suppression, diarrhea treatment, balanced anesthesia).
Naloxone (Narcan) Opioid Antagonist Indication: opioid toxicity/overdose
Pentazocine (Talwin) Opioid Agonist-Antagonist; Mild to moderate pain. MOA: Agonist at Kappa Antagonist at Mu
Sumatriptin (Imitrex) Triptan (Serotonin Receptor Agonist)Indication: Abortion of migrane headahces and cluster headaches. MOA: Serotonin agonist; selective receptors in brain, causes vasoconstriction (necessary) and suppresses inflammatory mediators.
Haloperidol (Haldol) 1st generation antipsychotic
Clozapine (Clozaril) 2nd generation antipsychotic
Imipramine (Tofranil) Tricyclic Antidepressant
Fluoxetine (Prozac) SSRI MOA: reuptake or serotonin. Indication: depression, anxiety disorders.
Duloxetine (Cymbalta) SNRI MOA: block reuptake of serotonin and norepinephrine. Indication: depression, anxiety disorders.
MAOI's MOA: irreversibly inhibit MAO enzyme (breaks down seretonin, NE and dopamine). Indication: depression refractory to SSRI and SNRI drugs.
Lithium salts Indication: bipolar disorder adjunct with anti epileptic drug.
Diazepam (Valium) Benzodiazepines Indication: chronic and acute anxiety, sleep disorders, muscle spasm, seizure, sedation, alcohol withdrawl, anti-epileptic, balanced anesthesia.MOA: Increase GABA in CNS
Pehenobarbital Barbituates
Methylphenidate (Ritalin, Concerta);Dextroamphetamine (Adderall, Adderall XXR) CNS Stimulant for ADD/ADHD MOA: Promote release of NE and inhibit reuptake of NE and Dopamine.
Created by: npeters519