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Lecture Unit 2

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Embryonic Brain Development Primary Brain Vesicles (Know Table in Lecture Guide).   Prosencephalon, Mesencphalon, Rhombencephalon  
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Secondary Brain Vesicles   Telencephalon, Diencephalon, Mesencphalon, Metencephalon, Myelencephalon. (Tel Di Mes Met My Mom).  
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Prosencephalon Becomes:   Telencephalon-cerebrum, lateral ventricles. Diencephalon- Epithalamus, thalamus, hypothalamus, Third ventricle.  
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Mesencphalon Becomes:   Mesencephalon-Midbrain (cerebral peduncles, corpora quadrigemina), Mesencephalic (Cerebral) aqueduct.  
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Rhombencephalon Becomes:   Metencephalon-Pons and cerebellum, Anterior part of fourth ventricle. Myelencephalon-Medulla oblongata, Posterior part of fourth ventricle.  
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Cranial Meninges   Connective tissue layers surrounding the BRAIN AND SPINAL CORD. Dura, arachnoid and pia maters. Functions: Separate brain from skull. Enclose & protect blood vessels supplying brain. Contain & circulate cerebrospinal fluid.  
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Brain Ventricles   Lateral Ventricles, Septum pellucidum, Third ventricle, Mesencephalic (cerebral) aqueduct, Fourth ventricle.  
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Cerebral Spinal Fluid (CSF)   Produced in the choriod plexus-made of ependymal cells. Clear, colorless. Circulates through ventricles. Functions: Buoyancy, Protection, Environmental stability-transports nutrients, chemical messengers, removes waste.  
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Hydrocephalus   "Water on the brain." Excessive CSF. Caused by: obstruction of CSF flow, Intrinsic problems w/ the arachnoid villi which drain CSF. Treatments:Ventriculoperitoneal shunt (VP). Endoscopic third ventriculostomy (EVT).  
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Cerebrum   Location of conscious thought processes. 2 hemispheres connected by corpus callosum. Gyri and sulci account for large cerebral surface area.  
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Cerebrum superficial gray matter   Cortex. Houses motor neurons cell bodies.  
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Cerebrum deep white matter   Houses myelinated axons  
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Lobes of the Cerebrum   Frontal, Parietal, Temporal, Occipital, Insula  
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Frontal Lobe   Decision making, personality, verbal communication, voluntary motor control of skeletal muscles.  
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Parietal lobe   Sensory interpretation of textures and shapes, understanding speech.  
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Temporal lobe   Auditory and olfactory experience  
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Occipital   Vision  
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Insula   Taste, memory  
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Frontal Lobotomy   "Cure" for people who were violent or profoundly disturbed. Japan: on children who did bad in school. USA: prisoners for early parole. 1930s-50s. Replaced by depression & psychiatric meds. Needle probe through eye area into brain.  
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Functional areas of the Cerebrum   Pre-central gyrus, Post-central gyrus, Association areas.  
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Pre-central gyrus   Contains primary motor cortex. Somatic motor control.  
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Post-central gyrus   Contains somatosensory cortex. Somatic sensory control.  
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Association areas   All cortical regions other than primary sensory and motor areas.  
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Homunculus   A map of the primary motor and sensory cortexes of the brain. Body part size corresponds to relative innervation of body part. Movement versus sensation.  
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Cerebral White Matter   ASSOCIATION TRACTS-connect dif parts of same hemisphere. COMMISSURAL TRACTS-connect hemispheres (corpus callosum). PROJECTION TRACTS-run vertically; convey sensory & motor information.  
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Diencephalon   Consists of thalamus, epithalamus, hypothalamus. Composed primarily of gray matter.  
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Epithalamus   Forms posterior roof of diencephalon & covers the third ventricle. HABENULAR NUCLEI-relays signals from the limbic system. Involved in the visceral & emotional responses to odors. PINEAL GLAND-secretes melatonin to regulate circadian rhythms.  
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Thalamus   Lies on either side of the third ventricle. Principle relay point for sensory & motor information into cerebrum. Interthalamic adhesion.  
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Hypothalamus Functions   Behavior, Endocrine, Emotion, Temperature control, Sleep/Wake cycles, Hunger/Thirst, Autonomic control, Memory (BEET SHAM)  
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Cerebellum   Smooths & coordinates body movements via: Info on equilibrium & posture, Info on current movements, Proprioception: Sensation of positions of body parts relative to each other, allows touching your nose w/ eyes closed. Hemispheres, vermis, arbor vitae.  
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Brain Stem   "Primitive Brain." Bidirectional passageway between cerebrum & spinal cord. Contains many autonomic & reflex centers essential for survival. Includes the mesencephalon, pons, & medulla oblongata.  
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Medulla Oblongata   Vasomotor center. Controls BP through vasoconstriction & vasodilation. Cardiac center. Respiratory center, Reflexes: coughing, sneezing, gagging, vomiting, etc. Point of attachment for cranial nerves.  
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Limbic System   "Emotional Brain." Involved in motivation, emotion, and memory.  
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Spinal Cord   Gray matter is deep. Central canal. Anterior, lateral, & posterior horns. White matter is superficial. Anterior, lateral, & posterior funiculi. Anterior median fissure, Posterior median sulcus, Dorsal root ganglion. Meninges.  
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Alzheimer Disease   Progressive degenerative disease of the brain. Results in dementia. 5-15% of people over 65 develop it. Symptoms: Mem loss, depression, disorientation. Caused by: Neurofibrillary tangles, Amyloid Precursor Proteins (APP) or senile plaques. Lose brain mass  
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Parkinson Disease   Affects muscle movement and balance. Symptoms, stiff posture, Expressionless face, slow movements, resting tremor, shuffling gait. Caused by lack of the neurotransmitter dopamine.  
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