EPINEPHRINE (ADRENALIN)
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| Class | Natural catechololamine Sympathomimetic
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| Discription | Epinephrine stimulates alpha-, beta1-, and beta2-adrenergic receptors in dose-related fashion. It is the initial drug of choice for treating bronchoconstriction and hypotension resulting from anaphylaxis as well as all forms of cardiac arrest. It is usefu
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| Onset Duration | Onset: (SQ) 5-10 min (IV) 1-2 min Duration: 5-10 min
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| Indications | Bronchial asthma Acute allergic reaction Cardiac arrest Asystole Electromechanical dissociation Ventricular fibrillation unresponsive to initial defibrillatory attempts
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| Contraindications | Hypersensitivity Hypovolemic shock Coronary insufficiency Hvpertension
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| Side Effects | Headache Nausea Restlessness Weakness Dysrhythmias Hypertension Precipitation of angina pectoris
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| How Supplied | Parenteral: 1 mg/ml ( 1: 1000), 0.1 mg/ml (1:10,000) ampule and prefilled syringe Autoin jector (EpiPen) 0.5 mg/ml (1:2000) 0.01 mg/ml ( 1: 100,000) pediatric
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| Dosage | Asystole, pulseless electrical activity, or ventricular fibrillation Adult: Initial: 1 mg IV push, repeat q 3-5 min Intermediate: 2-5 mg IV push q 3-5 min Escalating: 1 mg-3 mg-5 mg IV (3 min apart) High: 0.1 mg/kg IV push, q 3-5 min
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| Spicial Considerations | Pregnancy safety: Category C. Syncope has occurred after epinephrine administration to asthmatic children. May increase myocardial oxygen demand.
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| Actions | Both alpha and beta effects, increases hr, Myocardial contractily,Arterial BP,Systemic Vascular resistinance, Myocardio demand and Broncodilation. WILL ONLY WORK ON A WELL OXGENATTED MYOCARDIUM
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Created by:
fsneumann
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