AMYL NITRITE
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| Classification | Coronary vasodilator
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| Description | Related to NTG to Tx angina pectoris. Also effective in emergent mgt of cyanide poisoning by causing the oxidation of Hgb to the compound methemoglobin. Methemoglobin reacts with the cyanide ion to form cyanomethemoglobin, thus freeing Hgb to react with o
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| Onset/ Duration | 30 seconds inhaled Duration 3-30 minutes
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| Indications | Cyanide poising ANTIDOTE (only until sodium nitrate can be given IV) symptomatic angina pectoris
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| Contraindications | None when used for cyanide poisoning
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| Adverse reactions | Hypotension Tachycardia Palpitations Syncope HA N/V Visual disturbance
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| Precautions | Establish IV prior to admin, keep pt in supine position as hypotension may develop Drug has pungent odor & is highly flammable Medic take care not to inhale vapors
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| Supplied | 0.3 ml/glass ampule covered with woven gauze
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| Dosage | Same for adult & Ped ; break vaporole and inhale for 30 seconds while breathing 100% O2 repeat PRN pt ti be supine during admin – monitor BP
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| Special considerations | Frequently abused- claimed to be an aphrodisiac Cyanide poising often produces a bitter almond breath Oder
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Created by:
fsneumann
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