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DIAZEPAM (VALIUM) – (CONTROLED SUBSTANCE)

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Question
Answer
Classification   Sedative, Anticonvulsant  
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Pharm/Action   1) Tranquillizes calms patient 2) Suppresses seizure activity 3) Relaxes skeletal muscle  
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Indications   1) To seduce conscious patients when synchronized cardioversion is required or prior to intubation 2) As an anticonvulsant for seizures 3) As a skeletal muscle relaxant 4) Consider use in cocaine overdose  
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Contraindications   Contraindicated for pts with glaucoma ; hypersensitivity ETOH  
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Precautions   1) Use with caution in COPD patients or patients with respiratory depression (from any source) 2) Use with caution in hypotension patients  
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Side Effects   1) Transient hypotension 2) Reflex Tachycardia 3) Respiratory depression/ arrest 4) Dizziness Ataxia 5) Can cause local venous irritation  
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Administration   Adults 2-10mg SLOW IV bolus 2 mins Titrate until desired degree of sedation obtained or seizure activity is controlled IF UNABLE TO START IV ADMINISTER RECTALLY USING TEFLON IV CATH W/NEEDLE REMOVED OR 1CC SYRINGE  
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Special Notes   1) Should not be mixed with other drugs. Administer close to IV site followed by rapid flush 2) Synergistic effect when mixed with other CNS depressants (ETOH) 3) Requires hospital RN/physician witness for wasting of unused Rx  
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