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Immune System / HIV / Opportunistic Infections

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Answer
development of HIV antibodies; flu-like syndrome 1-3 weeks after injection   Seroconversion  
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*diagnositic tests ( most common) used to diagnose HIV & AIDS. *2 month window between infection and detection *positive detection takes between 2 weeks- 6 months   ELISA (enzyme-linked immunosorbent assay) and is confirmed by Western Blot Assay or Immunofluorenscence Assay (IFA)  
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Opportunistic Infection *gradual worsening tightening in chest and SOB *persistent, dry, non-productive cough, rales * dyspnea and tachypnea *low-grade/high fever *progressive hypoxemia and cyanosis   pneumocystis carinii (pneumonia)  
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CD4+T cells count drops below 500-600; oral thrush, headache, aseptic meningitis, peripheral neuropathies; cranial nerve palsy   Early Disease detection of HIV  
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Opportunistic Infection *changes in taste sensation *difficulty swallowing *retrosternal pain *white exudate and inflammation of mouth and back of throat   candida albican stomatitis (esophagitis)  
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Opportunistic Infection *fever, headache, and blurred vision *nausea and vomiting *stiff neck, mental status changes and seizures   Cryptococcus neoformans (severe, debilitating meningitis)  
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Opportunistic infection *significant factor in morbidity and mortality *fever and malaise, weight loss, fatigue *lymphadenopathy, visual impairment *colitis, encephalitis, pneumonitis *adrenalitis, hepatitis, disseminated infection *retinochoroiditis   Cytomegalovirus (CMV)  
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Opportunistic Infection *most common malignancy *small, purplish-brown, non-painful, nonpruritic, palpable lesions occuring on any part of the body *most commonly seen on the skin *diagnosed by biopsy   Kaposi's Carcinoma  
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contact with antigen (childhood diseases), develops slowly; protective within weeks; long-term and specific   active/natural aquired specific deficiency  
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immunization with antigen (immunization with live/killed vaccine) protective in a few weeks- lasts several years - booster often needed   active/artfical aquired specific deficiency  
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transplacental and colostrum transfer; temporary (lasts months)   passive/natural aquired specific deficiency  
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injection of serum from immune human/animal. Immediate immunity (lasts several weeks)   passive/artificial aquired specific deficiency  
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an RNA virus;replicates inside a living cell, transcribes into DNA, which enters cell nuclei, becoming a permanent part of genetic structure; can remain dormant for 8-10years as HIV;destroys CD4+T cells;cell count <200;opportunistic infections may occur   AIDS (aquired immunodeficiency syndrome)  
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Transmission of _______ occurs with contaminated blood or body fluid, sharing IV drug needles, sexual contact, transplacental, and possibly through breast milk   HIV/AIDS  
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what is recommended for diet/nutrition with a patient with HIV?   High Protein and Calories. No fresh vegetables/fruits.  
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what drugs (type) are used to treat HIV?   antiretroviral agents  
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a profound defect in the immune system that strikes previously healthy individuals who have no known cause for the immunosupression.   AIDS  
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a collection of protein molecules manufactured by B lymphocytes in response to the presence of specific antigens   Antibodies  
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specific substances that induce the development of an immune response   Antigens  
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direct, indirect, or droplet contact of an infectious agent to a host   contact transmission  
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one of the herpes-type viruses, commonly found in AIDS patients and also in well homosexuals   CMV  
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linked with Burkitts Lymphoma and with nasopharyngeal cancer. It is also the cause of monocucleosis common in adolescents and young adults. In the herpes virus family   Epstein-Barr Virus (EBV)  
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transmitted fecal-oral hepatitis virus   Hep A  
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hepatitis associated with liver cancer and transmitted by blood transfusions, mother to newborn, or through saliva, breast milk or genital secretions   Hep B  
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hepatitis transmitted blood to blood   Hep C  
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equips an individual to defend against infection   Immune system  
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the time between infection by a disease- causing organism and the onset or overt symptoms of the disease   incubation period  
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presence in the body of a pathogen   infection  
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a protein substance thought to be produced or released by cells after viral infection or by other stimuli   interferon  
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an abnormal condition of the lymph nodes and glads, in which the nodes enlarge, grow, swell and become palpable   Lymphadenopathy  
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oral structures throughout body that pass lymphocytes   lymphnodes  
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originate in the bone marrow, pass through blood stream, and enter other organs   lymphocytes  
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cells found in blood stream that act part of bodys immune system "eaters"   macrophages  
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various infectious organisms, (virus, fungi, parasites) which infect the immune system of a host that is compromised and cannot defend against a disease   opportunistic infections  
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microorganism or substance that is capable of producing diseases   pathogens  
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a form of pneumonia caused by a protozoan parasite   pneumocystitis carinii penumonia (PCP)  
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virus that are known to cause cancer in animals   retroviruses  
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a group of infections caused by viruses. The incubation periods are very long, and the clinical expressions of disease are low in progression   slow virus infections  
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removes worn-out cells from the circulatory system and is a "grave-yard" for RBC's, reintroducing iron from hemoglobin after red cell death   spleen  
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one of the subpopulations of T-lymphocytes that aid in the cytotoxic or killing function of T-lymphocytes   T-helper cells  
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responsible for the development of lymphocytes   thymus  
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redness, warmth, swelling, pain/tenderness, loss of function are all signs of __________.   inflammation with a localized infections  
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bloody, serous, cloudy, purulent are ________.   types of drainage with a localized infection  
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bacterial skin infection with involvment of connective tissue   cellulitis  
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weakness, headache, malaise, fever, increased, pulse, hypotension   generalized infections  
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most common nosocomial infection   UTI  
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most common nosocomial organism   staphylococcus aureus  
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what percentage of hospital patients aquire a nosocomial infection during their stay?   5% or nearly 2 million  
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how can you prevent nosocomial infections with your external environment?   handwashing  
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how can you prevent nosocomial infections with your internal environment?   good nutrition and personal hygiene  
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in what way can you prevent nosocomial UTI's?   strict aseptic technique during instrumentation  
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in what way can you prevent nosocomial surgical wound infections?   handwashing and surgical asepsis  
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in what way can you prevent nosocomial respiratory infections?   clean nebulizers  
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in what way can you prevent nosocomial bacteremias?   excellent sterile technique with intravascular systems  
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name standard precautions (PPE)   handwashing, gloves, masks, eye protection, face shield, gowns  
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when should you use standard precautions?   when you may come in contact with body fluids, blood, secretions, excretions (except sweat), nonintact skin, and mucous membranes  
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what is airborne precautions, and what precautions should be used?   pathogens are <5 microns transported in air.private room w/ negative air-pressure,door closed at all times & pt is not to leave room.Wear a mask & can only be combined if it is with a pt with the same organism. pt to wear mask when transported  
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what kind of mask is worn with a TB patient?   fit-test respirator mask  
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measles, tb, chickenpox, and shingles are all __________ precautions   airborne  
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what is droplet precautions, and what precautions should be used?   droplets >5microns. involves contact with mucous membranes through coughing, sneezing, talking, or suctioning. private room unless another pt with same organism.must wear mask if coming within 3 feet of pt. pt on mask if transported.door may be open  
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diptheria, pharyngitis, pneumonia, meningitis, mumps, influenza are all ____________ precautions   droplet  
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what is contact precautions, and what precautions should be used?   needed with pt care that require skin-to-skin contact or contact with inanimate objects in pts environment.private room or with pt with same organism.clean gloves when entering room; gown if coming in contact with pt. pt to wear gloves & gown leaving room  
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MRSA, VRE, pediculosis, scabies, herpes simplex, herpes zoster, hepatitis A, GI, wound or urinary infections, Cdiff are all _______ precautions   contact  
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what is neutropenic precautions, and what precautions should be used (part 1 of 2)?   prevent infection among clients with immunosupression. asses skin integrity Q8hrs;auscultate breath sounds, presence of cough, sore throat;check temp Q4hrs;monitor CBC;private room;thorough hand hygiene before entering room;no staff with temp/cold  
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what is neutropenic precautions, and waht precautions should be used (part 2 of 2)?   no fresh flowers or standing water; clean room daily; low microbial diet:no fresh salads,unpeeled fruits or veggies; deep breathe q4hrs; meticulous body hygiene; inspect IV site and give meticulous care  
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