Magnesium Sulphate
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| TYPE | Electrolyte solution
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| PRESENTATION | 50% solution (10mMol) 2.5g in 5ml vial
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| ACTION: | Magn is the 2nd most abundant intracellularcation. Less than 1% is present in extracellular fluidMagnesium is involved in the processes regulating Sodium and Potassium movement across cell membranes and it may promote myocardial cell membrane stability
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| Uses | 1. Torsades de pointes (polymorphic VT) (Often associated with prolonged QT interval) 2. Refractory VF 3. Digoxin and Tricyclic antidepressant toxicity 4. Seizures due to eclampsia
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| ADVERSE EFFECTS: | Rare; more common if serum Mg is normal. Respiratory depression; nausea & vomiting;hypotension; confusion; bradycardia.
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| CONTRA-INDICATIONS | AV block; renal failure; hepatic failure
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| PRECAUTIONS: | Myaesthenia gravis
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| Dose | CO: dilute up to 10mls with NS, 2.5g over 5min No CO: 2.5g over 30-60s Paed: 50mg/kg dilute to 10ml CO over 3-5min No CO over 30-60s
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| Special note | Prolonged hypotension post-Magnesium administration; if unresponsive to fluids, patient may be treated with IV Calcium. Consider use of Springfusor for patients with cardiac output
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Created by:
mattypepper
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