chapter 19
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| wha is the weight os hgb? | 1/3 of cell
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| how biconcave shaped help rbs? | increse surface area to volumen ratio
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| what biconcave shaped give to rbc? | a flexible shape for narrow passage capillaries
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| how new rbc enter the circulation? | at rate of 2 million second
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| how many hgb molecule per rbc? | 250-280 million hgb
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| how heme(fe)combine? | creversible with one oxigen molecule
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| how many billion atoms of oxigen in ech rbc? | 2 billion atoms of oxygen.
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| what hgb level and total number of rbc indicate? | oxygen carry capacity of blood/decresed level=getting tired.
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| what hgb carries? | both oxygen and carbon dioxide.
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| where oxigen is attach? | to iron of the heme of the hgb.
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| where carbon dioxide is attach? | amino acid /globin part of hgb.
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| more epo=? | decrese perfusion=flow incre blood presion.
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| how worn out cells are remove by? | fixed the macrophages in the spleen and liver.
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| where the recycled occurs? | liver and spleen.
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| the globin portion is broken down into? | amino acids and recycle.
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| how hemo portion is split? | into iron and biliverdin (green pigment.
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| where iron transpor in blood attach to? | tranferrin protein.
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| where iron in blood is stored? | liver,muscle,spleen and bone marrow /to be used for synthesis /decre fe=anemic,eat more iron/ice cube.
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| how biliverdin are converted to? | bilirubin(yellow)
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| where bilirubin is transported? | liver and secreted into bile.
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| what happen to exessive rbc destruction? | jaundice(yellow skin).
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| what is erythropoiesis? | production of rbc.
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| what is proerythroblast? | first baby red blood cell.
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| what step going 1-4 in erythropoiesis? | -reticulocyte escape-rbc form 5-7 days-proerythroblast star prod hgb-reticulocyte form.
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| what is the normal count of reticulocytes of circulating rbc? | 5% to 1.5% of circulating rbc.
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| low count of reticulocyte due to? | leukemia(too many wbc),nutricion deficiency oir failure of red bone marrow(b-12,iron,not enoutgh rbc) to respond to ery thropoietin stimulation.
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| hight count of teticulocyte? | indicate recent bood loss or successful iron therapy.
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| how reticulocyte count lead? | low rbc /need more vitamin b-12 and iron.
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| what is tisasue hypoxia is? | low oxygen due to high altituder or lower oxygen pressure cause anemia, low rbc production.
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| how kidney and liver respond in tissue hypoxia? | by releasing erythropoietig(make more rbc)
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| by kidney and liver respond speed up development of? | proerythroblast(baby first blood cell)into reticulocyte increase mature rbc.
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| proerythroblasts?? | first baby red blood cell/mature cell.
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| erythropoietin? | troduction of rbc.
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| reticulocytes? | count of circulation of rbc.
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