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cardiovascular syste

chapter 19

wha is the weight os hgb? 1/3 of cell
how biconcave shaped help rbs? increse surface area to volumen ratio
what biconcave shaped give to rbc? a flexible shape for narrow passage capillaries
how new rbc enter the circulation? at rate of 2 million second
how many hgb molecule per rbc? 250-280 million hgb
how heme(fe)combine? creversible with one oxigen molecule
how many billion atoms of oxigen in ech rbc? 2 billion atoms of oxygen.
what hgb level and total number of rbc indicate? oxygen carry capacity of blood/decresed level=getting tired.
what hgb carries? both oxygen and carbon dioxide.
where oxigen is attach? to iron of the heme of the hgb.
where carbon dioxide is attach? amino acid /globin part of hgb.
more epo=? decrese perfusion=flow incre blood presion.
how worn out cells are remove by? fixed the macrophages in the spleen and liver.
where the recycled occurs? liver and spleen.
the globin portion is broken down into? amino acids and recycle.
how hemo portion is split? into iron and biliverdin (green pigment.
where iron transpor in blood attach to? tranferrin protein.
where iron in blood is stored? liver,muscle,spleen and bone marrow /to be used for synthesis /decre fe=anemic,eat more iron/ice cube.
how biliverdin are converted to? bilirubin(yellow)
where bilirubin is transported? liver and secreted into bile.
what happen to exessive rbc destruction? jaundice(yellow skin).
what is erythropoiesis? production of rbc.
what is proerythroblast? first baby red blood cell.
what step going 1-4 in erythropoiesis? -reticulocyte escape-rbc form 5-7 days-proerythroblast star prod hgb-reticulocyte form.
what is the normal count of reticulocytes of circulating rbc? 5% to 1.5% of circulating rbc.
low count of reticulocyte due to? leukemia(too many wbc),nutricion deficiency oir failure of red bone marrow(b-12,iron,not enoutgh rbc) to respond to ery thropoietin stimulation.
hight count of teticulocyte? indicate recent bood loss or successful iron therapy.
how reticulocyte count lead? low rbc /need more vitamin b-12 and iron.
what is tisasue hypoxia is? low oxygen due to high altituder or lower oxygen pressure cause anemia, low rbc production.
how kidney and liver respond in tissue hypoxia? by releasing erythropoietig(make more rbc)
by kidney and liver respond speed up development of? proerythroblast(baby first blood cell)into reticulocyte increase mature rbc.
proerythroblasts?? first baby red blood cell/mature cell.
erythropoietin? troduction of rbc.
reticulocytes? count of circulation of rbc.
Created by: martha115