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Psych 4325 Drugs and Alcohol ch 2 notes

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Answer
Alveoli   Air sacs in th lungs that absorb oxygen or drugs into the blood  
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IV drug use   injectin a drug into a vein  
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Mucous membranes   Tissues lining the bose, gums, cheeks, etic, where drugs can be absorbed.  
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Insufflation   snorting a drug through the nose to be absorbed by nucous membranes  
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sublingual use   putting a drug under the tongue so it will be absorbed by mucous membranes  
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Capiliaries   tiny blood vessel lining the intestinal walls and mucous membranes that can absorb drugs  
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Contact absorption   drug absorbtion through the skin  
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Drug distribution   the process of getting a drug from its site absorbtion to the rest of the body  
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Blood-brain barrier   A barrier in the brain that allows only certain substances to penetrate  
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Central nervous system (CNS)   The brain and spinal cord that contains 100 billion nerve cells and 100 trillion connections  
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Peripheral nervous system (PNS)   A network of nerve cells that connect the central nervous system with it's internal and external environments  
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Autonomic nervous system   Part of the peripheral nervous system that controls involuntary internal functions such as circulation  
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Somatic nervous system   Part of the peripheral nervous system that transmits sensory information to the skin, muscles, and joints.  
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Evolutionary perspective   A theory that loks at physiological changes in the brian as survival adaptations  
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Old brain   Part of the brain in all animals that experiences basic emotions and cravings and imprints survival memories.  
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New brain   The neocortex or outer brain that allows us to speak, reason, create, and remember  
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Reward/Reinforcement center   Part of the old brain that encourages a human being to remeber and repeat an action that promotes survival  
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Mesolimbic dopaminergic reward pathway   Another name for the reward/reinforcement center.  
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Nucleus accumbens   Part of the reward reinforcement center that is a powerul reinforcer  
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Satiation center   The part of the brain that tells us when wer are satisfied.  
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Imprinting   The neural process of writing an emotional memory of euphoria or pain relief on the brain  
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On/Off switches   Parts of the brain that trigger craving and stop craving  
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Satiation point   The level of satisfaction that stops craving  
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Nerve cells (neurons)   Building clocks of the nervous system, each containing four essential parts: dendrites, the cell body, the axon, and terminals  
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Synaptic gap   The space between the terminal of one and the adjoining cell  
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Neurontransmitters   Microscopic bits of messenger chemicals that transmit messages from cell to another  
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Vesicles   Storage sacs in nerve cells that hold neurontransmitters  
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Endorphines/enkephalins   Pain control neurontransmitters developed inside the body.  
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Norepinephrine/epinephrine   Neurontransmitters that provide energy for the body  
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Dopamine   A neurotransmitter that stimulates the reward/reinforcement center  
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Serotonin   A neurotransmitter that helps control mood stability including depression and anxiety.  
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GABA   An inhibitory neurotransmitter involved in 25-40% of all synapses in the brain.  
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Anandamide   A neurotransmitter that has an affinity for receptor sites that accommodate the THC in marijuana  
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Receptor   A cellular mechanism on a nerve cell that is designed to receive a compatible neurotransmitter  
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Reuptake ports   Mechanisms on the tips of neurons that reabsorb neurontransmitters  
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Agonists   Psychoactive drugs that mimic or facilitate the effects of neurontransmitters  
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Antagonists   Psychoactive drugs that block neurontransmitters  
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Tolerance   The adaptation of the body to accommodate larger and larger amounts of a drug  
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Tissue dependence   Biological changes in the body due to prolonged use of drugs.  
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Psychological dependence   The formation of thoughts and emotions that create a mental dependence on a drug  
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Withdrawal   The body's attempt to rebalance itself after cessation of prolonged use of a psychoactive drug  
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Metabolism   The body's mechanism for processing, using, and inactivating a drug or food in the body.  
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Excretion   The process of eliminating drugs and their metabolites from the body.  
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Liver   The key metabolic organ that breaks down and process the chemical structure of drugs.  
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Kidneys   The key excretory organs that filter waste from the blood and into urine  
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Abstinence   Avoiding any use of a psychoactive drug  
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Experimentation   Occasional use of a drug to satisfy curiosity-only limited negative consequences.  
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Social/recreational   A level of drug use where the person seeks and uses a known drug but there is no established pattern  
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Habituation   A definite pattern of drug use with few negative consequences  
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Drug abuse   The continued use of a drug despite negative consequences  
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Addiction   Loss of control over drug use and continues use despite negative consequences  
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Substance-related disorders   A category of mental illnesses that includes substance use disorders and substance-induced disorders  
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Substance use disorders   Patterns of drug use especially substance dependence and substance abuse  
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Substance-induced disorders   Conditions caused by use of specific drugs intoxication, withdrawal, and certain mental disorders  
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Addictive disease model   This medical model maintains that addiction is most influenced by heredity  
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Behavioral/environmental model   The model says that environmental factors can change brain chemisty  
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Academic model   In this model, addition occurs when the body adapts to the toxic effects of drugs at the biochemical level.  
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Diathesis-stress theory of addiction   This theory says that genetic and environmental predisposition to substance abuse aggravated by drug use can cause addiction.  
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Heredity   The process whereby phsyical and behavioral traits are passed by genes from one generation to another  
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Twin studies   THe use of indentical twins raised in the same or in different environments to study the influence of heredity on addiction.  
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DRD2A1 Allele gene   The first gene discovered that signals a tendency to alcoholism(and other addictions)  
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Environmental influences   Factors that foster addiction including abuse, stress, family relationships, and peer pressure  
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SPECT scan   Single photon emission computerized tomography scan  
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PET scan   Positron emission tomography scan  
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CAT scan   Computereized axial tomography x-ray scan  
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MRI   Magnetic resonance imaging scan  
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