Chapter 10_IV Immunology
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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| It is the most common primary immunodeficiency. It is inherited. It is an extracellular bacterial infections of the mucosal surfaces, leading to respiratory, urogenital, and gastrointestinal infections. There is no specific immuno | Selective IgA deficiency
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| In a Selective IgA deficiency, the low secretory IgA (sIgA) concentration predisposes patients to extracellular bacterial infections of the mucosal surfaces, leading to_________. Some affected indiv | respiratory, urogenital, and gastrointestinal infections
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| It is a defect in the ability of phagocytes to kill bacteria. The disease is caused by a genetic defect in the production of oxygen radicals that are important for intracellular and extracellular killing of bacteria. | Chronic granulomatous disease (CGD)
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| _________ produce a transient immunodeficiency. | Acute infections
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| It is the more common subtype of human immunodeficiency virus in the United States and western Europe. | HIV-1
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| bone marrow transplantation | Severe combined immunodeficiency disorders (SCIDs) occur in the first few months postnatally, & survival for longer than 1 yr is rare without successful _________________.
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| Chronic granulomatous disease (CGD) | It is a defect in the ability of phagocytes to kill bacteria. The disease is caused by a genetic defect in the production of oxygen radicals that are important for intracellular and extracellular killing of bacteria.
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| X-linked | The Chronic granulomatous disease (CGD) is a defect that can occur in any of the four proteins essential for producing oxygen radicals, but the most common defect is______.
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| _________ act in concert with genetic predisposition to induce disease.
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| Antithyroid autoimmunity | This is an example of Organ-specific disorder.
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| Organ-specific disorders | These disorders are limited to and directed specifically against self-antigen in a single organ. Lesions and clinical symptoms are limited primarily to that organ.
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