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Immunodeficiency
Chapter 10_IV Immunology
Question | Answer |
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It is the most common primary immunodeficiency. It is inherited. It is an extracellular bacterial infections of the mucosal surfaces, leading to respiratory, urogenital, and gastrointestinal infections. There is no specific immuno | Selective IgA deficiency |
In a Selective IgA deficiency, the low secretory IgA (sIgA) concentration predisposes patients to extracellular bacterial infections of the mucosal surfaces, leading to_________. Some affected indiv | respiratory, urogenital, and gastrointestinal infections |
It is a defect in the ability of phagocytes to kill bacteria. The disease is caused by a genetic defect in the production of oxygen radicals that are important for intracellular and extracellular killing of bacteria. | Chronic granulomatous disease (CGD) |
_________ produce a transient immunodeficiency. | Acute infections |
It is the more common subtype of human immunodeficiency virus in the United States and western Europe. | HIV-1 |
bone marrow transplantation | Severe combined immunodeficiency disorders (SCIDs) occur in the first few months postnatally, & survival for longer than 1 yr is rare without successful _________________. |
Chronic granulomatous disease (CGD) | It is a defect in the ability of phagocytes to kill bacteria. The disease is caused by a genetic defect in the production of oxygen radicals that are important for intracellular and extracellular killing of bacteria. |
X-linked | The Chronic granulomatous disease (CGD) is a defect that can occur in any of the four proteins essential for producing oxygen radicals, but the most common defect is______. |
_________ act in concert with genetic predisposition to induce disease. | |
Antithyroid autoimmunity | This is an example of Organ-specific disorder. |
Organ-specific disorders | These disorders are limited to and directed specifically against self-antigen in a single organ. Lesions and clinical symptoms are limited primarily to that organ. |