HM2 lilk8tob Childhood cancers
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Most common leukemia in children, especially boys | ALL
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ALL stands for | Acute Lymphocytic Leukemia
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AML stands for | Acute Mylocytic leukemia
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In this acute leukemia, subtypes determine the prognosis and the treatment | ALL
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This acute leukemia has a good prognosis for kids, poor for adults | ALL
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In this leukemia, try chemo up to the 3rd relapse, then do BMT | ALL
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ALL: best dx if leukocytes are:, age:, gender: , chromosomes: | leukocytes <50,000; 3-9 years old; female; >50 chromosomes
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In ALL, pre-B cell subtype and FABL are: | the best dx
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In this acute leukemia, subtypes don't direct treatment | AML
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This acute leukemia is most common in adults | AML
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This acute leukemia has a poor prognosis for everyone | AML
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For this acute leukemia, do BMT on 1st remission | AML
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CLL stands for | Chronic Lymphocytic Leukemia
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CML stands for | Chronic Myelogenous Leukemia
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This chronic leuk is very rare in kids, and is most common in men age 50+ | CLL
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This chronic leuk is caused by a neoplasm of activated B lymphocyte cells that accumulate in bone marrow lymph nodes and spleen | CLL
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CLL Signs and symptoms | fatigue, GU symptoms, abd. pain, anemia
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This chronic leuk has no treatment | CLL
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the progression of this chronic leuk is 9-15 years | CLL
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This leuk has the Philadelphia chromosome | CML
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In this chronic leuk, there is an excessive development of neoplastic granulocytes in bone marrow | CML
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The chronic phase of this leuk lasts 2-4 years, then it can go into a blastic phase that resembles AML | CML
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This chronic leuk uses drugs to avoid acute phase | CML
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The only curative treatment for CML: | BMT
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A chronic, progressive disorder c/b painless enlargement of lymph nodes w/ predictable progression to spleen, liver & bone marrow | Hodgkin's lymphoma
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This has the proliferation of Reed-Sternberg cells (they replace other cell elements) | Hodgkin's lymphoma
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In children w/ this, the "sentinel" node in the supraclavicular area is seen first | Hodgkins
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W/ Hodgkins, pain in the lymph node is experienced with ingesting: | alcohol
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Does Hodgkin's have a good long-term survival rate? | Yes, with aggressive chemo and radiation
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This is a malignancy of B&T lymphocytes | Non-Hodgkin's lymphoma (NHL)
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This disease has a possible viral etiology | Non-Hodgkins lymphoma
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Non-Hodgkins lymphoma is seen more often in: | immunocompromised pts
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Age for Non-Hodgkins | less than 14, over 40
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Which Hodgkin's is harder to diagnose? | Non-Hodgkins is
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The less predictable of the hodgkis | Non
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Signs and symptoms of non-hodgkin's | enlarged lymph nodes, night sweats, stomach cramps, constipation
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This condition (increased uric acid levels) may occur with Non-Hodgkins | Tumor lysis syndrome
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Is an adult w/ low grade (slow progression) non-hodgkins more or less responsive to treatment? | Less responsive
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Location of brain tumors in children | Below the Tentorium Cerebri
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Location of brain tumors in adults | Above the Tentorium cerebri
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Big sign of brain tumor in adults: | Headache because the skull can't swell
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Big sign of brain tumor in children (and the reason) | Enlarged head because fontanel and sutures allow the head to swell
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Is "benign" a good thing for kid's brain tumors | No- it really just depends on the location- if can't be reached, will kill surrounding tissue & cause problems
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In kids, S&S of brain tumor: | Morning vomiting, poor coordinatino, visual changes, increased ICP
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Infant brain tumor S&S | Irritability, poor feeds, increased head size, loss of developmental milestones
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Adult brain tumor S&S | HA when waking, N/V, visual changes, personality changes, seizures are common, papilledema of the optic nerve
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Treatment of brain tumors: | GAMMA knife - pinpoint radiatiion, chemo, brachytherapy
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Radiation used for brain tumors after age: | three
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Treatment where you put the med or radioactive seed directly into brain: | Brachytherapy
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Things to warn family about before brain surgery: | head shaved, large dressing, HOB 30 degrees
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After brain surgery for tumor, watch for these two things: | SIADH (syndrome of inappropriate ADH) and Diabetes
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Position to avoid after brain surgery: | Trendelenburg
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This is one of the worst tumors (in children only) because it is the hardest to find and treat | Neuroblastoma
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A neuroblastoma originates from: | embryonic adrenal/sympathetic chain cells
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What is the "silent tumor" | Neuroblastoma because it is well metastasized before S&S
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This tumor in children can randomly disappear on it's own somehow | Neuroblastoma
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Neuroblastoma is more common in (race & gender) | White boys
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This tumor is a firm non tender mass that WILL CROSS THE MIDLINE | neuroblastoma tumor
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If neuroblastoma found after 1 year, survival rate: | 50%
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This is the most common renal cancer | Wilms tumor
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This tumor has a peak incidence of 3 yrs old, and does have genetic inheritence | Wilms tumor
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This tumor does NOT CROSS THE MIDLINE | Wilm's tumor
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S&S of Wilm's tumor | hematuria, anemia (from bleeding), HTN (from increased secretion of renin)
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Wilm's tumor commonly metastasizes to the: | lungs
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If have Wilm's tumor, will remove: | kidney and adrenal gland
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Key nursing fact for pt with Wilm's tumor: | Do not palpate the abdomen- can rupture the tumor!
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Pt has Wilm's tumor- must monitor | BP - have increased secretion of renin
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This is a striated muscle tumor | Rhabdomyosarcoma
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Rhabdomyosarcomas in young children are most often found: | in the head, neck and eye orbit
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Rhabdomyosarcomas in older children are most often found: | in the trunk and extremities
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Treatment for rhabdomyosarcoma | chemo to reduce bulk, then surgery, radiation
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If relapse within two years with rhabdomyosarcoma | prognosis is very poor
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Rhabdomyosarcoma survival rate | 65%
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Name the two bone tumors: | Osteogenic sarcoma and ewing's sarcoma
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This is the most common bone cancer | Osteogenic sarcoma
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When do osteogenic sarcomas peak (age)? | Teen years- rapid bone growth
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Treatment for Osteogenic sarcoma | amputation of leg, attempt arm-sparing procedure
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This tumor arises from bone forming mesenchyme malignant osteoid | osteogenic sarcoma
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S&S of osteogenic sarcoma | limp, palpable mass, fractures
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Osteogenic sarcoma usually located at | distal femur and knee
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Osteogenic sarcoma frequently metastizes to: | lungs
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This tumor arises in marrow spaces of bone and mimics infection | Ewing's sarcoma
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Peak age for ewing's sarcoma | 10-20 years old
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Metastasis for Ewing's: | metastasis uncommon at diagnosis, but can occur to marrow and lungs
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S&S of Ewing's | pain and swelling around site, fever, limp/decreased ROM
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Treatment of Ewing's | Chemo to shrink tumor, surgery to resect primary tumor or radiation
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This is a congenital malignant tumor that arises from the retina | Retinoblastoma
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A retinoblastoma results from | A series of genetic mutations
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Reflex seen in pts with retinoblastoma | "Cat's eye" reflex- leukoria
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S&S of retinoblastoma | cat's eye, strabismus, pain, blindness
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Metastasis common in retinoblastoma | bone metastasis- so assess bone marrow
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Treatment for retinoblastoma | enucleation (eye removal) if optic nerve is involved, chemo only with metastatic disease
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Type of counseling needed with retinoblastoma | genetic counseling- is inherited (esp. the bilateral kind)
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