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HM2 lilk8tob Childhood cancers

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Most common leukemia in children, especially boys   ALL  
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ALL stands for   Acute Lymphocytic Leukemia  
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AML stands for   Acute Mylocytic leukemia  
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In this acute leukemia, subtypes determine the prognosis and the treatment   ALL  
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This acute leukemia has a good prognosis for kids, poor for adults   ALL  
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In this leukemia, try chemo up to the 3rd relapse, then do BMT   ALL  
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ALL: best dx if leukocytes are:, age:, gender: , chromosomes:   leukocytes <50,000; 3-9 years old; female; >50 chromosomes  
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In ALL, pre-B cell subtype and FABL are:   the best dx  
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In this acute leukemia, subtypes don't direct treatment   AML  
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This acute leukemia is most common in adults   AML  
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This acute leukemia has a poor prognosis for everyone   AML  
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For this acute leukemia, do BMT on 1st remission   AML  
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CLL stands for   Chronic Lymphocytic Leukemia  
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CML stands for   Chronic Myelogenous Leukemia  
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This chronic leuk is very rare in kids, and is most common in men age 50+   CLL  
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This chronic leuk is caused by a neoplasm of activated B lymphocyte cells that accumulate in bone marrow lymph nodes and spleen   CLL  
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CLL Signs and symptoms   fatigue, GU symptoms, abd. pain, anemia  
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This chronic leuk has no treatment   CLL  
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the progression of this chronic leuk is 9-15 years   CLL  
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This leuk has the Philadelphia chromosome   CML  
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In this chronic leuk, there is an excessive development of neoplastic granulocytes in bone marrow   CML  
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The chronic phase of this leuk lasts 2-4 years, then it can go into a blastic phase that resembles AML   CML  
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This chronic leuk uses drugs to avoid acute phase   CML  
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The only curative treatment for CML:   BMT  
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A chronic, progressive disorder c/b painless enlargement of lymph nodes w/ predictable progression to spleen, liver & bone marrow   Hodgkin's lymphoma  
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This has the proliferation of Reed-Sternberg cells (they replace other cell elements)   Hodgkin's lymphoma  
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In children w/ this, the "sentinel" node in the supraclavicular area is seen first   Hodgkins  
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W/ Hodgkins, pain in the lymph node is experienced with ingesting:   alcohol  
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Does Hodgkin's have a good long-term survival rate?   Yes, with aggressive chemo and radiation  
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This is a malignancy of B&T lymphocytes   Non-Hodgkin's lymphoma (NHL)  
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This disease has a possible viral etiology   Non-Hodgkins lymphoma  
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Non-Hodgkins lymphoma is seen more often in:   immunocompromised pts  
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Age for Non-Hodgkins   less than 14, over 40  
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Which Hodgkin's is harder to diagnose?   Non-Hodgkins is  
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The less predictable of the hodgkis   Non  
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Signs and symptoms of non-hodgkin's   enlarged lymph nodes, night sweats, stomach cramps, constipation  
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This condition (increased uric acid levels) may occur with Non-Hodgkins   Tumor lysis syndrome  
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Is an adult w/ low grade (slow progression) non-hodgkins more or less responsive to treatment?   Less responsive  
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Location of brain tumors in children   Below the Tentorium Cerebri  
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Location of brain tumors in adults   Above the Tentorium cerebri  
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Big sign of brain tumor in adults:   Headache because the skull can't swell  
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Big sign of brain tumor in children (and the reason)   Enlarged head because fontanel and sutures allow the head to swell  
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Is "benign" a good thing for kid's brain tumors   No- it really just depends on the location- if can't be reached, will kill surrounding tissue & cause problems  
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In kids, S&S of brain tumor:   Morning vomiting, poor coordinatino, visual changes, increased ICP  
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Infant brain tumor S&S   Irritability, poor feeds, increased head size, loss of developmental milestones  
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Adult brain tumor S&S   HA when waking, N/V, visual changes, personality changes, seizures are common, papilledema of the optic nerve  
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Treatment of brain tumors:   GAMMA knife - pinpoint radiatiion, chemo, brachytherapy  
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Radiation used for brain tumors after age:   three  
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Treatment where you put the med or radioactive seed directly into brain:   Brachytherapy  
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Things to warn family about before brain surgery:   head shaved, large dressing, HOB 30 degrees  
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After brain surgery for tumor, watch for these two things:   SIADH (syndrome of inappropriate ADH) and Diabetes  
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Position to avoid after brain surgery:   Trendelenburg  
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This is one of the worst tumors (in children only) because it is the hardest to find and treat   Neuroblastoma  
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A neuroblastoma originates from:   embryonic adrenal/sympathetic chain cells  
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What is the "silent tumor"   Neuroblastoma because it is well metastasized before S&S  
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This tumor in children can randomly disappear on it's own somehow   Neuroblastoma  
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Neuroblastoma is more common in (race & gender)   White boys  
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This tumor is a firm non tender mass that WILL CROSS THE MIDLINE   neuroblastoma tumor  
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If neuroblastoma found after 1 year, survival rate:   50%  
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This is the most common renal cancer   Wilms tumor  
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This tumor has a peak incidence of 3 yrs old, and does have genetic inheritence   Wilms tumor  
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This tumor does NOT CROSS THE MIDLINE   Wilm's tumor  
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S&S of Wilm's tumor   hematuria, anemia (from bleeding), HTN (from increased secretion of renin)  
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Wilm's tumor commonly metastasizes to the:   lungs  
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If have Wilm's tumor, will remove:   kidney and adrenal gland  
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Key nursing fact for pt with Wilm's tumor:   Do not palpate the abdomen- can rupture the tumor!  
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Pt has Wilm's tumor- must monitor   BP - have increased secretion of renin  
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This is a striated muscle tumor   Rhabdomyosarcoma  
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Rhabdomyosarcomas in young children are most often found:   in the head, neck and eye orbit  
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Rhabdomyosarcomas in older children are most often found:   in the trunk and extremities  
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Treatment for rhabdomyosarcoma   chemo to reduce bulk, then surgery, radiation  
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If relapse within two years with rhabdomyosarcoma   prognosis is very poor  
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Rhabdomyosarcoma survival rate   65%  
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Name the two bone tumors:   Osteogenic sarcoma and ewing's sarcoma  
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This is the most common bone cancer   Osteogenic sarcoma  
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When do osteogenic sarcomas peak (age)?   Teen years- rapid bone growth  
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Treatment for Osteogenic sarcoma   amputation of leg, attempt arm-sparing procedure  
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This tumor arises from bone forming mesenchyme malignant osteoid   osteogenic sarcoma  
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S&S of osteogenic sarcoma   limp, palpable mass, fractures  
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Osteogenic sarcoma usually located at   distal femur and knee  
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Osteogenic sarcoma frequently metastizes to:   lungs  
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This tumor arises in marrow spaces of bone and mimics infection   Ewing's sarcoma  
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Peak age for ewing's sarcoma   10-20 years old  
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Metastasis for Ewing's:   metastasis uncommon at diagnosis, but can occur to marrow and lungs  
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S&S of Ewing's   pain and swelling around site, fever, limp/decreased ROM  
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Treatment of Ewing's   Chemo to shrink tumor, surgery to resect primary tumor or radiation  
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This is a congenital malignant tumor that arises from the retina   Retinoblastoma  
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A retinoblastoma results from   A series of genetic mutations  
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Reflex seen in pts with retinoblastoma   "Cat's eye" reflex- leukoria  
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S&S of retinoblastoma   cat's eye, strabismus, pain, blindness  
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Metastasis common in retinoblastoma   bone metastasis- so assess bone marrow  
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Treatment for retinoblastoma   enucleation (eye removal) if optic nerve is involved, chemo only with metastatic disease  
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Type of counseling needed with retinoblastoma   genetic counseling- is inherited (esp. the bilateral kind)  
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