Comprehensive Cards
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Drugs that readily pass through the blood-brain barrier are... | show 🗑
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show | tolerance
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Six rights of drug administrations are... | show 🗑
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Water solubility, reduced blood flow, ionized, small surface area, and bowel hyperactivity are... | show 🗑
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show | blood brain, blood-eye, or fetal placental
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Impact of protein binding on drug distribution is... | show 🗑
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show | liver
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Size of doses needed for drugs with a high first pass effect: | show 🗑
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show | decrease in amount needed
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Ratio between lethal dose of a drug and effective dose is called... | show 🗑
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This organ must be mature and healthy in order to effectively excrete drugs: | show 🗑
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Routes which avoid first pass effect are: | show 🗑
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Non-protein bound, water soluble, ionized: | show 🗑
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Safety level of drugs with a narrow therapeutic range: | show 🗑
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Amount of time required for the 50% of a dose to be eliminated | show 🗑
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Type of drug that mimics the actions of the body's own regulatory molecules: | show 🗑
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Type of drug that prevents receptor activation by endogenous regulatory molecules and have no effect of their own: | show 🗑
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Effect of food on rate of drug absorption: | show 🗑
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show | increases drug levels (can create toxic effect)
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show | iatrogenic
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show | LFT (tests AST and ALT levels)
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show | BUN, creatinine
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Test used to monitor for bone marrow suppression: | show 🗑
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Proven risk of fetal harm: | show 🗑
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show | Administer just after breastfeeding, use drugs that are water-soluble with a short half-life
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About 10% of individuals are allergic to this class of antimicrobials: | show 🗑
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show | cephalosporins
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show | epinephrine
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show | vancomycin
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Antimicrobial that discolors teeth and can cause enamal loss--withhold pregnancy and less than 8 yr.: | show 🗑
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show | erythromycin
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Major toxic effects of this class of antimicrobials are ototoxicity and nephrotoxicity: | show 🗑
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This antimicrobial has a higher risk for photosensitivity: | show 🗑
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show | sulfonamides (sulfamethexazole)
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show | metronidazole
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This antimicrobial can produce a disulfiram-like reaction if comined with alcohol: | show 🗑
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show | Amphotericin B
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show | acyclovir
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Contraindicated for persons with hypersensitivity to eggs: | show 🗑
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Enfavirtide (Fuzeon), zidovudine (Retrovir), efavirenz (Sustiva), Lopinavir (Kaletra), and nelfinavir (Viracept): | show 🗑
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Reduction in viral load: | show 🗑
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Levodopa, Levodopa with Carbidopa (Sinemet), Amantadine (Symmetrel), and Benztoprine (Cogentin) are... | show 🗑
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Length of time to wait betwen administration of last dose of Levodopa and first dose of Sinemet: | show 🗑
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To avoid abrupt cessation of this prototype drug's effects--spread out protein intake throughout the day: | show 🗑
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show | Levodopa
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Tacrine (Cognex) and Memantine (Namenda) are drugs to treat... | show 🗑
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Phenytoin (Dilantin) carbamazepine (tegretol), valproic acid (depakote), diazepam (valium), and phenobarbital (barbiturate) are... | show 🗑
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DOC for treatment of status epilepticus: | show 🗑
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show | Dilantin
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show | Benzodiazepines (Diazepam/Lorazepam)
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show | Morphine/Fentanyl
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Prototype opioid antagonist: | show 🗑
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show | respiratory depression
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show | twelve
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show | opioids
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show | acetaminophen
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Sumatriptan (Imitrex) and ergotamine are... | show 🗑
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show | Cox 2 (aspirin)
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Tinnitus, sweating, headache, and dizziness are symptoms of what type of drug toxicity? | show 🗑
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show | aspirin
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show | acetylcholine
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show | eyes, arterioles, veins, bladder
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Location of beta 1 sympathetic system receptors: | show 🗑
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show | lungs
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Response to activation of alpha 1 receptors: | show 🗑
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Response to activation of beta 1 receptors: | show 🗑
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Response to activation of beta 2 receptors: | show 🗑
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show | pupil constriction
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show | decreased heart rate, no release of renin
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Response to blockade of beta 2 receptors: | show 🗑
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show | increased urine output
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show | pupil constriction
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Response to blockade of muscarinic receptors in the lungs: | show 🗑
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show | decrease in output
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Response to blockade of muscarinic receptors on the heart: | show 🗑
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Prototype drug used to treat hypertension by blockade of alpha 1 receptors: | show 🗑
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show | Propanolol/Atenolol/Metaprolol
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Prototype cholinergic (muscarinic) agonist used to treat urinary retention: | show 🗑
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Prototype cholinesterase inhibitor used to treat myasthenia gravis: | show 🗑
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Antidote for too much cholinesterase inhibitor or too much cholinergic agonist: | show 🗑
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Prototype cholinergic (muscarinic) antagonist: | show 🗑
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show | pupil dilation
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Drugs which increase contractility are: | show 🗑
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Class of drugs which prevent the conversion of angiotensin 1 to angiotension 2: | show 🗑
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show | water and sodium excretion (lowers blood pressure)
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Effect of blockade of the converstion of angiotension 1 to angiotension 2 on vascular smooth muscle: | show 🗑
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Strategies for "first dose" hypotension: | show 🗑
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show | 100
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show | 60
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Potential adverse effect of all antihypertensives | show 🗑
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Rate at which furosemide (Lasix) is given IV in order to avoid hypotension: | show 🗑
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Normal (therapeutic) digoxin level: | show 🗑
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Effect of dopamine and dobutamine on cardiac contractility (output): | show 🗑
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Cardiosuppressant effects on heart rate, contractility (CO) and AV conduction: | show 🗑
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Adverse effect of all vasodilators: | show 🗑
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show | statins
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show | Questran (cholestyramine)
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Used for hypertensive crises. Adverse effects include hypertension, cyanide poisoning, and thiocyanate toxicity: | show 🗑
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Toxicity that is characterized by bradycardia, GI symptoms, and CNS effects like visual disturbances. Toxicity is potentiated by hypokalemia: | show 🗑
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show | ARB's (angiotensin receptor blockers)
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This class of drugs have generic names that end in "pril": | show 🗑
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This class of drugs have generic names that end in "olol": | show 🗑
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show | ACE inhibitors and ARB's
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Clients taking this antihypertensive agent must be monitored for hypokalemia: | show 🗑
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show | ACE inhibitors
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Digoxin, Dopamine, Dobutamine are referred to as: | show 🗑
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show | 1st choice: Ferrous sulfate; 2nd choice: Iron dextran
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show | cyanocobalamin
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show | folic acid
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show | Epogen
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Leukopoietic growth factor: | show 🗑
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Thrombopoietic growth factor: | show 🗑
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DOC for prevention of arterial thromboses: | show 🗑
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Thrombolytic: | show 🗑
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DOC for prevention of venous thromboses: | show 🗑
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Antidote for heparin: | show 🗑
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show | Vitamin K
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Expected change in stool appearance with iron administration: | show 🗑
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show | analphylactic reaction (IV/IM)
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show |
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show | bone pain
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show | fluid retention, cardiac dysrhythmias
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show | CBC, iron level
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Lab test to monitor effectiveness of epoeitin alfa (Epogen): | show 🗑
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show | CBC, platelets
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show | CBC, platelets
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Lab test to monitor effectivenes of warfarin: | show 🗑
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Lab test to monitor effectiveness of heparin: | show 🗑
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Target aPTT range for heparin anticoagulation: | show 🗑
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Target PT range for warfarin anticoagulation: | show 🗑
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Target INR range for warfarin anticoagulation: | show 🗑
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show | low (normal=5,000-10,000)
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Interpretation of a platelet count of 35,000: | show 🗑
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Potential adverse effect of heparin therapy: | show 🗑
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show | Heparin
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Expected onset of Warfarin effects: | show 🗑
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Timeframe in which thrombolytics must be administred following symptom onset: | show 🗑
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show | bleeding, hypotension
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show | Streptokinase
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Interpretation of a peak flow meter reading in the yellow zone: | show 🗑
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Inhaled beta 2 agonist used for quick relief during an asthma attack: | show 🗑
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Tachycardia, angina, and tremor can be adverse effects of this bronchodilator if taken in excess: | show 🗑
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Pseudoephedrine (Sudafed) and phenylphrine (Neosynephrine): | show 🗑
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Diphenhydramine (Benadryl), Loratadine (Claritin), and Azelastine (Astelin): | show 🗑
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Expected action of guafenesin (Mucinex): | show 🗑
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show | reacts directly with mucus which results in increased water content of secretions
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show | Glucocorticoids
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show | rebound congestion
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Adverse effect of first generation antihistamines: | show 🗑
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A leukotriene modifier: | show 🗑
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show | Cromolyn (Intal)
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Oropharyngeal candidiasis and dysphonia are possible adverse effects of this inhaled prototype drug: | show 🗑
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With this prototype drug use to prophylactically treat asthma the nurse must monitor for toxicity. Therapeutic range is 10-20 mcg/ml. | show 🗑
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Created by:
fambrough
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