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Uworld

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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show Vasospasm occurs 3-12 days after and CT usually remains unchanged Rebleeding occurs soon after (<24 hours) and results in changes in CT  
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show Cavernous hemangioma Micro: Cavernous blood filled vascular spaces lined by a single epithelial layer  
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2nd generation antipsychotics   show
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show Calcium and vit D  
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show When a large area of cells is exposed to carcinogens that induce mutations (Common in mucosal head and neck squamous cell carcinoma).  
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Topical immunomodulatory agent that stimulates potent cellular and cytokine based immune response by activating TLRs on aberrant cells (like HPV infected cells)   show
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show Membranous glomerulopathy  
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Decompensated HF is a common cause of secondary>   show
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Used to detect and quantify levels of mRNA of a sample   show
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The probability that a sibling would be an identical HLA match is:   show
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Complications of hereditary spherocytosis   show
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show Weak points of the colonic wall, where the vasa recta penetrate through the smooth muscle.  
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What is the Reid index?   show
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Rotavirus infection causes diarrhea via multiple mechanisms including>   show
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show The villous epithelium of the duodenum and proximal jejunum  
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show Rotavirus  
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Test specificity   show
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show Reduced RPF Reduced GFR Increased FF (compensatory arteriolar vasoconstriction)  
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show Integrin mediated binding to fibronectin, collagen and laminin. Adhesion properties defects seen in numerous malignancies (melanoma)  
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Polyarteritis nodosa (PAN) is often associated with underlying>   show
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show Mediated by viral surface glycoproteins that bind to host cell receptors. Mutations can cause non infectious viruses to become infectious.  
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show Selective dorsal rhizotomy (Disruption of the afferent sensory arm of the stretch reflex)  
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show Free RBCs (hematuria) and crystals consistent with the type of stone.  
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Glycogen formation is stimulated by increased levels of>   show
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show Systemic or ophthalmic glucocorticoid use, DM, ocular trauma and external radiation exposure.  
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The infusion of excessive normal saline (sodium chloride) is a common cause of>   show
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show Carbamazepine  
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SIADH presents with> And is the opposite of >   show
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show Endogenous catecholamines Hypotension, bradycardia, bronchospasm, hypoglicemia.  
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Can be co-administered with dopamine receptor blockers to prevent excessive cholinergic activity in the treatment of severe migraine.   show
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Is a proto-oncogene often activated in tumor cells, thereby increasing the cellular response to mitogenic stimuli   show
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Stimulate cell proliferation and their over-expression/amplification leads to increased cell proliferation and neoplastic growth   show
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show Loop diuretics (inhibit Na-K-2Cl) Thick ascending limb of loop of Henle  
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The replacement of enzymes needs to be administered via >   show
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show Propionibacterium acnes  
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Results in a blowing holosystolic murmur best heard over the cardiac apex with radiation to the axila>   show
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show Dilation of the left ventricular cavity. Heart failure decompensation.  
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show Chronic pancreatitis  
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show Ganglion cysts Most resolve spontaneously.  
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Examples of active transport carriers> Drugs that can inhibit it>   show
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Contain high levels of mitochondria, lipids and myoglobin. Their function is amplified by endurance training.   show
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show TB meningitis Presents with subacute, slowly progressive nausea, vomiting, fever, cranial nerve deficits and stroke.  
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show 1) Macrocytosis 2) AST: ALT ratio>2  
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show Piperacillin-tazobactam (Tazobactam is a beta lactamase inhibitor)  
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show Health care proxy  
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Changes during pregnancy: SVR, plasma blood volume   show
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Anterior cord syndrome, affected tracts and manifestations>   show
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show Low oncotic pressure  
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show Acute pulmonary edema. Increased hydrostatic pressure in the pulmonary venous system leads to engorged alveolar capillaries with fluid transudation (acellular pink material on histology).  
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show When a pair of alleles are inherited together in the same gamete (haplotype) more or less often than expected by chance alone. Often the result of physical proximity of genes.  
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show Subdural hematoma After fall or accidents in young patients, after minor trauma in elderly.  
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What is biliary sludge? What does it cause?   show
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show Prolonged hypoxia. Patients with lung cancer, TB, CF, empyema, bronchiectasis and chronic lung abscesses.  
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Iron deficiency anemia may result in which nail finding?   show
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show Cholinesterase inhibitors (donepezil) Antioxidants ( vit E) NMDA receptors antagonists (memantine)  
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show Elevated levels of estrogen and progesterone decrease the muscle tone of the LES. Later in pregnancy can happen due to uterus pressure on the stomach.  
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show Accumulation of intracellular Na+ and water due to failure of ATP dependent ion transporters.  
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Increased hydrostatic pressure following central venous thrombosis or hypertensive encephalopathy can cause>   show
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Is responsible of the physiologic adaptations in hypothermia>   show
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show HER2  
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show Monoclonal antibody that blocks HER2, downregulates cellular proliferation and promotes apoptosis.  
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Biopsy of salivary glands in patients with Sjogren syndrome>   show
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show Follicular epidermal hyperproliferation (androgens, anabolic steroids) Excessive sebum production Inflammation Propionibacterium acnes  
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Most common triggers of drug induced hemolysis>   show
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show Body fat redistribution Subcutaneous lipoatrophy involving the face and extremities linked to nucleoside reverse transcriptase inhibitors (stavudine, zidovudine) and protease inhibitors.  
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Area of the brain that demonstrates higher degree of atrophy in Alzheimer's disease   show
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show Synaptophysin, chromogranin and neuron-specific enolase.  
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Celiac disease is characterized by>   show
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show Mucor and Rhizopus.  
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show Haemophilus ducreyi "So painful you do cry"  
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show Loud holosystolic murmur best heard over the lower left sternal border.  
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Increased O2 saturation between two right-sided vessels or chambers indicates de presence of>   show
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show Fibroblast growth factor 23 (FGF23) Reduces intestinal absorption and renal reabsorption of phosphate.  
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Anti-nuclear antibodies are the most characteristic feature of>   show
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show Induce methemoglobinemia.  
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