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chapter 12

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Term
Definition
Agranulocytes   White blood cells that lack granules in the cytoplasm: a: without granul/o: granules cyte: cells  
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antibodies   destroys substances  
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antibody-mediated immunity   immunity resulting from B-cell  
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antigens   substances that triggers immune response  
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atria (singular atrium)   Thin walled chambers of the heart that receives blood from the veins.  
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atrioventricular valves   valves between the atria and ventricles of the heart; tricuspid on the right side, mitral on the left side. atri/o: atrium ventricul/o: ventricle  
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cardiac cycle   a complete heartbeat consisting of contraction and relaxation of both atria and both ventricles  
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cell-mediated immunity   immunity T cells action  
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coagulation   the process of blood clotting: coagul /o: clotting tion: process  
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conduction myofibers   part of conduction system Purkinje fibrous  
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diapedesis   Leukocytes squeeze between cells in vessel walls Dia: through  
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Diastole   relaxation phase of the cardiac cycle; opposite of systole  
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endocardium   the thin, smooth inner lining of each chamber of the heart, that permits blood to move easily. endo: around, outside card/i: heart um: tissue  
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erythrocytes   red blood cells. erythr/o: red  
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erythropiesis   the process of erythrocyte formation. poieses: formation  
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erythropoietin   a hormone released by the kidneys that stimulate red blood cell production. poietin: substances that form  
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granulocytes   granules in the cytoplasm of a cell:  
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hematopoiesis   erythrocyte production in the red bone marrow  
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hemocytoblast   a stem cell in the bone marrow hem/o : blood blast: to form  
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hemoglobin   the iron-containing protein in red blood cells that is responsible for the transport in oxygen. globin: protein  
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hemostasis   The control or stoppage of bleeding  
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immunoglobulins   destroys substances ; antibodies immun: immunity or protection  
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leukocytes   white blood cells  
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macrophage   large phagocytic tissue cell phage: to eat  
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megakaryocyte   a large cell that contributes to the formation of platelets. mega: large kary/o: nucleus  
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myocardium   middle layer of the heart wall; cardiac muscle, provides the force to eject blood from the heart to the vessels. my/o: muscle um: tissue  
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non specific defense mechanism   body's ability to counter act many types of harmful agents  
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pericardial cavity   small space around the heart,  
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pericardium   membrane that surrounds the heart; usually refers to the pericardial sac.  
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pulmonary circulation   the pathway that takes blood from the right side of the heart to the lungs and then returns it to the left side of the heart. pulmon- lung  
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renal erythropoietic factor   a substance produced by the kidneys that activates erythropoietin to stimulate the production of red blood cells. ren/o: kidney poie: formation of blood cells  
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resistance   body's ability to counteract the effects of pathogens and other harmful agents.  
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right lymphatic duct   the collecting duct of the lymphatic system that collects lymph from the upper right quadrant of the body  
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semilunar valves   valves between the ventricles of the heart and the vessels that carry blood away from the ventricles; also pertains to the valves in the veins.  
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specific defense mechanism   activities of the body that counteract only certain types of harmful agents.  
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susceptibility   lack of resistance to disease  
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systemic circulation   pathways that transport blood from the left side of the heart to all parts of the body and return the blood to the right atrium; excludes pulmonary circulation.  
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systole   contraction phase of the cardiac cycle; opposite of diastole  
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thoracic duct   the primary collecting duct of the lymphatic system that collects lymph from all regions of the body except the upper right quadrant  
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thrombocytes   a class formed elements of the blood; function in blood clotting; also called platelets. Blood clotting cells. thrombo/o: clot  
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ventricle   pumping chambers of the heart;  
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epicardium   outer layer of the heart, blood vessels that nourish the heart.  
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Albumins   produced in the liver, protein in urine, assists in fluid balance  
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globulins   antibodies that function in immunity  
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eosinophils   segmented nucleus, 2 lobes, large granules, bright reddish orange, surrounds histamine, and increase their amount during an allergic reaction.  
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basophils   very few, large, S-shaped nucleus, coarse granules, black and blue colored. secretes histamine that dilates blood vessels, and heparin anticoagulant.  
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lymphocyte   large, round, purpleish-blue cytoplasm. contains few to none granules. functions in the immune system and assists with the production of antibodies.  
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Thrombocytes   fragments of bigger cells that are not complete cells. plug and closes breaks and tears in the blood vessels.  
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lymphatic system 3 primary functions.   Returns extra fluid to blood. Absorption of fats and vitamins. defense against invading microorganisms and disease  
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formed elements   RBC WBC Thrombocytes  
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lymphatic organs   lymph nodes, tonsils, spleen, thymus  
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aging of the circulatory system   left ventricle shrinks. thickening of the endocardium and valves of the heart. valves become more rigid.  
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coronary   blood vessels that nourish the heart of the wall  
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left atrium   receives oxygenated blood from lungs  
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ventricle   right ventricle pumps blood into the lungs left ventricle pumps blood into the systemic circulation  
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systemic circulation   pathway of the blood that transports blood from the left side of the heart through out the body.  
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monocyte   largest, U-shaped nucleus, abundant cytoplasm, stained grayish-blue, becomes macrophage, last responder to clean up remaining bacteria.  
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heart   located between the two lungs posterior to the sternum anterior to the vertebral column rests on the diaphragm  
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circulatory system   heart, blood , blood vessels, lymph, lymphatic vessel, lymphatic organs  
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inter-ventricular septum   the thick, muscular partition between the right and left ventricle.  
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neutrophils   purple multi-lobed nucleus, first responders to tissue damage, engulfs bacteria, increases during acute infection  
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leukocytes   there are five types of WBC: NEUTROPHILS, EOSINOHILS, BASOPHILS, MONOCYTE, LYMPHOCYTES. WBC are white and colorless before they get stained.  
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fibrinogen   clotting process  
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plasma proteins   albumin, globulin, fibrogen  
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AV bundle   "bundle of his" electrical fiber that triggers the myocardium to contract and relax. purkinje fibers.  
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Artery   carrys blood away from hearts and has 3 layers. tunica intima - inner tunica media - middle tunica externa - outer layer  
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lymphatic vessels   carry fluid away from tissue, the flow of the lymph is slow and sluggish.  
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functions of blood   transportation, regulation, protection.  
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left ventricle   pumps blood to the whole body  
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left atrium   receives oxygenated blood from the inferior vena cava.  
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lymph node   inguinal nodes- groin axillary nodes- armpit cervical node- in the neck  
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tonsils   pharyngeal (adenoids) - nasal cavity Palatine - oral cavity lingual - base of the tongue  
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size of the heart   9cm wide 12cm long  
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Atherosclerosis   signs and symptoms: chest pain, in heart, in brain, ischemic attacks, kidney dysfunction. diagnosis: P.E, medical history, blood test, doppler ultra sounds. treatment: healthy diet, blood thinners, stent bypass.  
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coronary artery disease (CAD)   signs and symptoms: chest pain, dyspnea, arrhythmias, fatigue. diagnosis: P.E, medical history, stress test, treatment: asprin, bypass surgery, healthy lifestyle  
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cardiomypathy   signs and symptoms: chest pain, dyspnea, peripheral edema Diagnosis: P.E, echocardium, blood test, ECG treatment: pacemaker, defibrillator, LVAD, ablation, heart transplant  
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IgG   75%-85% , located in the plasma. function: inactivates antigen, neutralizes toxins, responsible for rh reaction.  
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IgA   5%-15%, found in saliva, mucus, tears, breast milk. function: protects mucous membrane from body surfaces; provides immunity for newborn.  
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IgM   5%-10%, attached to b cells, released into the plasma during immune response. function: causes antigens to clump together, responsible for transfusion reactions in ABO blood typing system  
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IgD   .2% attached to b cells. binding with antigen results in b cell activation  
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IgE   .5% produced by plasma cells in mucous membranes and tonsils. binds to basophils, causing release of histamine, responsible for allergic reactions.  
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active natural   contract disease and produce memory cell  
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active artificial   receive a vaccination and produce memory cell  
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passive natural   receive maternal antibodies through the placenta or breast milk  
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passive artificial   receive antiserum with antibodies from another host  
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