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ATI 140

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Term
Definition
Prototype   is the drug providers most commonly prescribe  
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Generic Name   official, not capitalized  
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Brand Name   commercial name, Capitalized  
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Pharmaceutics   address how various drug forms affect dissolution, absorption rate, and onset of action.  
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Oral Drugs   by mouth, forms are tablets, capsules and liquids or through mouth but inhaled into lungs-usually in powder form.  
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Delayed Release   (ER) Extended Release (XL) Extended Length (SR/XR) Sustained Release (SA) Sustained Action  
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Pharmacokinetics   describes the absorption, distribution, metabolism, and excretion of drugs.  
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Absorption   is the movement of the drug from site of administration to various tissues of the body  
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Distribution   is the movement of the drug by circulatory system to intended site of action- Rich blood supply areas receive most drug-liver, kidneys, and heart.  
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Biotransformation   is the change that occurs in a drugs chemical nature (primarily in the liver.  
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Metabolite   New or altered version of the drug (post metabolism)  
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Excretion   is the elimination of a drug, or its metabolites, through the kidneys (which may re-absorb through kidneys again), gi tract, skin, and lungs  
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Half life of a drug   Time it takes for a drug to decrease in amount by half.  
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Peak level   drug highest level in the body  
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Trough Level   drugs lowest level in the body  
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Pharmacodynamics   biochemical changes that occur in the body as a result of taking a drug  
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therapeutic effects   Intended effects of the drug  
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Side/Adverse effects   unintended effects of the drug  
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Agonist   Drugs that bind to receptor sites to precipitate greater than typical response  
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Antagonist   Drugs that bind to receptor sites to block response or lessen the typical response  
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Selective Interaction   drug can change target molecules typical response by inhibiting or enhancing the action of an enzyme  
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Anaphylactic Shock   Exaggerated response of bodies immune system to a drug-Precipitates massive release of histamine and other chemical mediators  
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Drug Tolerance   Body's decrease response to drug it receives over period of time-for therapeutic effect, dosage must increase. Tolerance to narcotic drugs can result after 10-14 days  
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Cumulative Drug Effects   occur when amount of drug patient received is greater than rate it is excreted-Common in older adults who have decrease in cardiac and kidney function and patients who have liver or kidney disease. Will need decrease in dosage.  
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Airborne Precautions   measures taken to prevent the spread of diseases transmitted from an infected person by pathogens propelled through the air on particles smaller than sum in size to a susceptible person's eyes, nose, or mouth.  
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Antibody   A type of protein the immune system produces to neutralize a threat of some kind, such as an infecting organism, a chemical, or some other foreign body.  
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Antimicrobial   Able to destroy or suppress the growth of pathogens and other micro-organisms  
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Antiseptic    
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Asepsis   Methods used to assure that an environment is as pathogen free as possible.  
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Aseptic   As pathogen free as possible  
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