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ATI 140
| Term | Definition |
|---|---|
| Prototype | is the drug providers most commonly prescribe |
| Generic Name | official, not capitalized |
| Brand Name | commercial name, Capitalized |
| Pharmaceutics | address how various drug forms affect dissolution, absorption rate, and onset of action. |
| Oral Drugs | by mouth, forms are tablets, capsules and liquids or through mouth but inhaled into lungs-usually in powder form. |
| Delayed Release | (ER) Extended Release (XL) Extended Length (SR/XR) Sustained Release (SA) Sustained Action |
| Pharmacokinetics | describes the absorption, distribution, metabolism, and excretion of drugs. |
| Absorption | is the movement of the drug from site of administration to various tissues of the body |
| Distribution | is the movement of the drug by circulatory system to intended site of action- Rich blood supply areas receive most drug-liver, kidneys, and heart. |
| Biotransformation | is the change that occurs in a drugs chemical nature (primarily in the liver. |
| Metabolite | New or altered version of the drug (post metabolism) |
| Excretion | is the elimination of a drug, or its metabolites, through the kidneys (which may re-absorb through kidneys again), gi tract, skin, and lungs |
| Half life of a drug | Time it takes for a drug to decrease in amount by half. |
| Peak level | drug highest level in the body |
| Trough Level | drugs lowest level in the body |
| Pharmacodynamics | biochemical changes that occur in the body as a result of taking a drug |
| therapeutic effects | Intended effects of the drug |
| Side/Adverse effects | unintended effects of the drug |
| Agonist | Drugs that bind to receptor sites to precipitate greater than typical response |
| Antagonist | Drugs that bind to receptor sites to block response or lessen the typical response |
| Selective Interaction | drug can change target molecules typical response by inhibiting or enhancing the action of an enzyme |
| Anaphylactic Shock | Exaggerated response of bodies immune system to a drug-Precipitates massive release of histamine and other chemical mediators |
| Drug Tolerance | Body's decrease response to drug it receives over period of time-for therapeutic effect, dosage must increase. Tolerance to narcotic drugs can result after 10-14 days |
| Cumulative Drug Effects | occur when amount of drug patient received is greater than rate it is excreted-Common in older adults who have decrease in cardiac and kidney function and patients who have liver or kidney disease. Will need decrease in dosage. |
| Airborne Precautions | measures taken to prevent the spread of diseases transmitted from an infected person by pathogens propelled through the air on particles smaller than sum in size to a susceptible person's eyes, nose, or mouth. |
| Antibody | A type of protein the immune system produces to neutralize a threat of some kind, such as an infecting organism, a chemical, or some other foreign body. |
| Antimicrobial | Able to destroy or suppress the growth of pathogens and other micro-organisms |
| Antiseptic | |
| Asepsis | Methods used to assure that an environment is as pathogen free as possible. |
| Aseptic | As pathogen free as possible |
Created by:
kkmoore1981
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