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ATI 140

TermDefinition
Prototype is the drug providers most commonly prescribe
Generic Name official, not capitalized
Brand Name commercial name, Capitalized
Pharmaceutics address how various drug forms affect dissolution, absorption rate, and onset of action.
Oral Drugs by mouth, forms are tablets, capsules and liquids or through mouth but inhaled into lungs-usually in powder form.
Delayed Release (ER) Extended Release (XL) Extended Length (SR/XR) Sustained Release (SA) Sustained Action
Pharmacokinetics describes the absorption, distribution, metabolism, and excretion of drugs.
Absorption is the movement of the drug from site of administration to various tissues of the body
Distribution is the movement of the drug by circulatory system to intended site of action- Rich blood supply areas receive most drug-liver, kidneys, and heart.
Biotransformation is the change that occurs in a drugs chemical nature (primarily in the liver.
Metabolite New or altered version of the drug (post metabolism)
Excretion is the elimination of a drug, or its metabolites, through the kidneys (which may re-absorb through kidneys again), gi tract, skin, and lungs
Half life of a drug Time it takes for a drug to decrease in amount by half.
Peak level drug highest level in the body
Trough Level drugs lowest level in the body
Pharmacodynamics biochemical changes that occur in the body as a result of taking a drug
therapeutic effects Intended effects of the drug
Side/Adverse effects unintended effects of the drug
Agonist Drugs that bind to receptor sites to precipitate greater than typical response
Antagonist Drugs that bind to receptor sites to block response or lessen the typical response
Selective Interaction drug can change target molecules typical response by inhibiting or enhancing the action of an enzyme
Anaphylactic Shock Exaggerated response of bodies immune system to a drug-Precipitates massive release of histamine and other chemical mediators
Drug Tolerance Body's decrease response to drug it receives over period of time-for therapeutic effect, dosage must increase. Tolerance to narcotic drugs can result after 10-14 days
Cumulative Drug Effects occur when amount of drug patient received is greater than rate it is excreted-Common in older adults who have decrease in cardiac and kidney function and patients who have liver or kidney disease. Will need decrease in dosage.
Airborne Precautions measures taken to prevent the spread of diseases transmitted from an infected person by pathogens propelled through the air on particles smaller than sum in size to a susceptible person's eyes, nose, or mouth.
Antibody A type of protein the immune system produces to neutralize a threat of some kind, such as an infecting organism, a chemical, or some other foreign body.
Antimicrobial Able to destroy or suppress the growth of pathogens and other micro-organisms
Antiseptic
Asepsis Methods used to assure that an environment is as pathogen free as possible.
Aseptic As pathogen free as possible
Created by: kkmoore1981