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Pharm Ch. 1,3,6,7,8

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Question
Answer
Allergic Reaction   Patient sensitivity to a medication because of an immune response  
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Physical dependence   Patient's body adapts to medication to medication and will experience physical withdrawals without it  
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Anaphylactic reaction   Life threatening response characterized by bronchospasm, laryngeal edema, and drop in BP  
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Toxicity   Adverse drug reaction caused by excessive dosing  
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Side effect   An expected but unpleasant effect that occurs in addition to the desired effects of a drug  
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Iatrogenic effect   When a drug causes symptoms of a medical condition  
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Teratogenic effect   When a medication has an effect that causes harm to the fetus of a pregnant patient  
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Carcinogenic effect   The ability of certain meds and environmental chemicals to cause cancer  
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Idiosyncratic effect   An uncommon response to a drug by a patient, often related to a genetic predisposition  
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Paradoxical effect   When a patient has the opposite response to a drug from what is expected  
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Additive effect   Two drugs have a combined effect. This may be positive or negative  
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Synergistic effect   Two drugs have more of an effect combined than they would of each were given on their own  
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Adverse effect   Annoying to potentially life threatening effects of a drug that may occur at normal doses  
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Antagonistic effect   Two drugs combined decrease the effects of each other  
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Important determinants of drug response?   Dosage, route, time  
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Boxed warnings   Strongest safety warning a drug can carry and still remain on the market  
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Medication guides   Patient education documents about medications  
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Fatal medication errors   Overdose, wrong route, and wrong drug All of these are due to human factors - performance/knowledge deficits , communication mistakes, drug name confusion  
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Ways to reduce medication errors?   Communication, documentation, medication reconciliation, callback - read back, barcode scanning, support systems  
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Pharmacokinetics   AMDE  
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3 properties of ideal drugs   Effective, safety, selectivity  
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