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Pharm Ch. 1,3,6,7,8
Question | Answer |
---|---|
Allergic Reaction | Patient sensitivity to a medication because of an immune response |
Physical dependence | Patient's body adapts to medication to medication and will experience physical withdrawals without it |
Anaphylactic reaction | Life threatening response characterized by bronchospasm, laryngeal edema, and drop in BP |
Toxicity | Adverse drug reaction caused by excessive dosing |
Side effect | An expected but unpleasant effect that occurs in addition to the desired effects of a drug |
Iatrogenic effect | When a drug causes symptoms of a medical condition |
Teratogenic effect | When a medication has an effect that causes harm to the fetus of a pregnant patient |
Carcinogenic effect | The ability of certain meds and environmental chemicals to cause cancer |
Idiosyncratic effect | An uncommon response to a drug by a patient, often related to a genetic predisposition |
Paradoxical effect | When a patient has the opposite response to a drug from what is expected |
Additive effect | Two drugs have a combined effect. This may be positive or negative |
Synergistic effect | Two drugs have more of an effect combined than they would of each were given on their own |
Adverse effect | Annoying to potentially life threatening effects of a drug that may occur at normal doses |
Antagonistic effect | Two drugs combined decrease the effects of each other |
Important determinants of drug response? | Dosage, route, time |
Boxed warnings | Strongest safety warning a drug can carry and still remain on the market |
Medication guides | Patient education documents about medications |
Fatal medication errors | Overdose, wrong route, and wrong drug All of these are due to human factors - performance/knowledge deficits , communication mistakes, drug name confusion |
Ways to reduce medication errors? | Communication, documentation, medication reconciliation, callback - read back, barcode scanning, support systems |
Pharmacokinetics | AMDE |
3 properties of ideal drugs | Effective, safety, selectivity |