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Medical-Surgical Nursing

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
What is HIV?   Human immunodeficiency virus  
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What type of virus is HIV?   Retrovirus  
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What is reverse transcriptase?   An enzyme that transforms the RNA of HIV into a single strand of DNA  
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How does HIV integrate into the host's genetic structure?   Through the enzyme integrase  
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How many stages exist in untreated HIV?   3  
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What is Stage 1 of HIV infection?   Acute HIV infection  
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What are the signs and symptoms of acute (Stage 1) HIV infection?   Within 2-4 weeks of infection, patients experience flu-like illness  
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What are diagnostic tests to diagnose acute HIV infection?   Either a fourth generation antibody/antigen test or a nucleic acid test (NAT)  
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When are patients with HIV most infectious?   During the acute (stage 1) phase  
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What are possible neurologic complications with acute HIV infection?   Aseptic meningitis, peripheral neuropathy, facial palsy, or Guillan-Barre syndrome  
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What is Stage 2 of HIV infection?   Clinical latency (Inactivity or dormancy)  
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What are signs and symptoms during Stage 2 of HIV infection?   Patients are asymptomatic  
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How long is the interval between initial HIV infection and diagnosis of AIDS in untreated infection?   Generally 10 years  
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What is Stage 3 of HIV infection?   Acquired immunodeficiency syndrome (AIDS)  
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What are common signs and symptoms of AIDS?   Persistent fever, chills, sweats, swollen lymph nodes, chronic diarrhea, recurrent headaches, weight loss, and severe fatigue  
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What is the required CD4+ T cell count required by the CDC to diagnose AIDS?   Less than 200 cells  
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How does the enzyme protease affect HIV?   It's involved in the replication process of the viral DNA, allowing it to spread  
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What virus causes Kaposi sarcoma?   Human herpesvirus 8  
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What is a common cancer associated with AIDS?   Kaposi sarcoma  
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How does Kaposi sarcoma appear?   As purple, brown, or red tumors (called lesions) on the skin and mucosal surfaces  
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Do the lesions of Kaposi sarcoma usually cause symptoms?   No  
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If HIV positive, what antigen is produced before antibodies develop?   p24  
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What is the normal range of CD4+ T cells?   800-1200 cells  
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True or False: No test can detect HIV immediately after exposure.   True  
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Who is more likely to get HIV: A circumcised man or an uncircumcised man?   An uncircumcised man  
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If an HIV-positive woman has an undetectable viral load, can she safely breastfeed?   No; her breast milk can still transmit HIV  
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What is PrEP?   Pre-exposure prophylaxis is a comprehensive HIV prevention strategy to reduce the risk of sexually-acquired HIV in high risk patients  
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What drugs are used in PrEP?   A combination of tenofovir and emtricitabine (Truvada)  
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What is PEP?   Post-exposure prophylaxis; taking antiretrovirals (ART) after being potentially exposed HIV  
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When must PEP be started?   Within 72 hours of possible exposure to HIV  
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Is PEP 100% effective in preventing HIV?   No  
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What is defined as viral suppression?   Having less than 200 copies of HIV per mL of blood  
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What is lipodystrophy?   Changes in body shape r/t a redistribution of fat in the abdomen, upper back, and breasts along with fat loss in the arms, legs, and face  
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What is the target cell for HIV?   CD4+ T cells  
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What type of cell is the CD4+ T cell?   Lymphocyte  
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What bodily fluids transmit HIV?   Blood, semen, vaginal secretions, and breast milk  
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What is the most common mode of HIV transmission?   Unprotected sexual contact with an HIV-infected partner.  
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